Written at Fredericksburgh. Comments on the arrival of (the privateer) General Arnold's prize. Thinks the British will leave the United States to secure their possessions elsewhere, noting that an attempt to capture the French fleet at Boston rests on too many uncertainties for the British. Recently received news that the French captured the island of Dominica, which Knox refers to as Dominico. Also reports that France sent 4,000 men to take Jamaica. Comments that the British have taken cattle and forage in New Jersey, and surprised [Colonel George] Baylor's regiment, wounding Baylor (this battle is referred to as the Baylor Massacre, 28 September 1778). Writes, But should the Enemy contrary to my reasonings, conjectures & conclusions be so insane as to push to Boston, you may rely I shall give you the earliest notice- But rest easy on this head. Discusses a business matter handled by William related to Henry's mortgage and estate. Also mentions an unspecified petition. Contains several notes written in a different hand throughout text. Minor text loss from seal. Mentions that Lucy and her baby, possibly their daughter Lucy, are both well. On page four, Knox reports that General Benjamin Lincoln will soon take command in Charleston South Carolina.