Vaya Nuevo Stage 1 Cassette 1a
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| Author | : Michael Buckby |
| Publisher | : Nelson Thornes |
| Total Pages | : 180 |
| Release | : 1994 |
| Genre | : Foreign Language Study |
| ISBN | : 9780174396680 |
This three-stage new edition of this Spanish course for beginners leads to public examinations. !Vaya! have been consulted and their sugges tions have been incorporated into this new edition. It has been written to meet the requirements of the National Curriculum and the 5-14 Guidelines. Stages 1, 2 and 3 of !Vaya! Nuevo should prepare students for GCSE/Key Stage 4 examinations and Standard Grade.
| Author | : Paul Davies |
| Publisher | : |
| Total Pages | : |
| Release | : 2021-11 |
| Genre | : |
| ISBN | : 9780982372449 |
A collection of essays from the English Language Teaching in Latin America website, collected and edited by Paul Davies between 2018 and 2020.
| Author | : James W. Heisig |
| Publisher | : University of Hawaii Press |
| Total Pages | : 0 |
| Release | : 2012-04-30 |
| Genre | : Foreign Language Study |
| ISBN | : 9780824836696 |
Following the first volume of Remembering the Kanji, the present work provides students with helpful tools for learning the pronunciation of the kanji. Behind the notorious inconsistencies in the way the Japanese language has come to pronounce the characters it received from China lie several coherent patterns. Identifying these patterns and arranging them in logical order can reduce dramatically the amount of time spent in the brute memorization of sounds unrelated to written forms. Many of the “primitive elements,” or building blocks, used in the drawing of the characters also serve to indicate the “Chinese reading” that particular kanji use, chiefly in compound terms. By learning one of the kanji that uses such a “signal primitive,” one can learn the entire group at the same time. In this way, Remembering the Kanji 2 lays out the varieties of phonetic pattern and offers helpful hints for learning readings, that might otherwise appear completely random, in an efficient and rational way. Individual frames cross-reference the kanji to alternate readings and to the frame in volume 1 in which the meaning and writing of the kanji was first introduced. A parallel system of pronouncing the kanji, their “Japanese readings,” uses native Japanese words assigned to particular Chinese characters. Although these are more easily learned because of the association of the meaning to a single word, the author creates a kind of phonetic alphabet of single syllable words, each connected to a simple Japanese word, and shows how they can be combined to help memorize particularly troublesome vocabulary. The 4th edition has been updated to include the 196 new kanji approved by the government in 2010 as “general-use” kanji.
| Author | : John Butt |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 533 |
| Release | : 2012-12-06 |
| Genre | : Foreign Language Study |
| ISBN | : 1461583683 |
(abridged and revised) This reference grammar offers intermediate and advanced students a reason ably comprehensive guide to the morphology and syntax of educated speech and plain prose in Spain and Latin America at the end of the twentieth century. Spanish is the main, usually the sole official language of twenty-one countries,} and it is set fair to overtake English by the year 2000 in numbers 2 of native speakers. This vast geographical and political diversity ensures that Spanish is a good deal less unified than French, German or even English, the latter more or less internationally standardized according to either American or British norms. Until the 1960s, the criteria of internationally correct Spanish were dictated by the Real Academia Espanola, but the prestige of this institution has now sunk so low that its most solemn decrees are hardly taken seriously - witness the fate of the spelling reforms listed in the Nuevas normas de prosodia y ortograjia, which were supposed to come into force in all Spanish-speaking countries in 1959 and, nearly forty years later, are still selectively ignored by publishers and literate persons everywhere. The fact is that in Spanish 'correctness' is nowadays decided, as it is in all living languages, by the consensus of native speakers; but consensus about linguistic usage is obviously difficult to achieve between more than twenty independent, widely scattered and sometimes mutually hostile countries. Peninsular Spanish is itself in flux.
| Author | : Susanne Holzknecht |
| Publisher | : |
| Total Pages | : 242 |
| Release | : 1989 |
| Genre | : Austronesian languages |
| ISBN | : |
| Author | : Ralph N. Martins |
| Publisher | : John Wiley & Sons |
| Total Pages | : 548 |
| Release | : 2019-07-10 |
| Genre | : Technology & Engineering |
| ISBN | : 1119356784 |
Understanding the impact of diet, exercise, genetics, and hormones on the risk and development of Alzheimer’s and other neurogenerative diseases Diet is widely known to impact on neurological function. Nevertheless, academic texts discussing this relationship are relatively few in number. This book therefore fills an important gap in the current literature. Opening with an overview of neurodegenerative diseases, particularly Alzheimer’s disease, the text then focuses on explaining the means by which glycemic control and lipid metabolism – and associated nutritional and lifestyle variables – may factor into such disorders’ prevention and treatment. An international group of experts in the fields of food science and neurodegeneration have contributed chapters that examine Alzheimer’s disease within a broad range of contexts. Offering dietary, genetic, and hormonal perspectives, the authors explore topics ranging from sugar consumption to digestive fermentation, and Alzheimer’s disease animal models to the cognition-enhancing effects of physical exercise. Also included are overviews of the latest research into current and developing methods of treatment and diagnosis, as well as differential diagnostics. This groundbreaking book: Explores how glucose metabolism, insulin resistance, lipid metabolism, and high intake of refined carbohydrates are linked to Alzheimer's disease Discusses how genetic makeup can impact risk of Alzheimer’s and Parkinson’s disease Examines cognitive changes in neurodegeneration, lists current tests for determining cognitive impairment, and provides information concerning differential diagnosis Discusses potential advantages of increasing antioxidant and micronutrient intake Reviews hormonal influences on neurodegeneration Examines the links between protein intake and Alzheimer’s disease. Neurodegeneration and Alzheimer's Disease is an essential resource for researchers, medical practitioners, dietitians, and students with an interest in neurological diseases and their diagnosis and risk factors, as well as diet-related conditions such as diabetes and obesity. Lifestyle and diet influence neurodegeneration risk, and a better understanding of this evidence amongst health professionals will hopefully lead to greater public awareness of how to reduce the likelihood of these widespread conditions.
| Author | : Lucio G. Costa |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 244 |
| Release | : 2002-11-30 |
| Genre | : Medical |
| ISBN | : 9781402072826 |
The journey to find genes responsible for determining sensitivity or resistance to specific insecticides led to the paraoxonase (PON1) gene on human chromosome 7. This gene encodes a 355 amino acid protein that is localized on the high density lipoprotein (HDL) particles in plasma. Characterization of this gene revealed that different individuals expressed both different forms of this enzyme with amino acid substitutions at positions 55 and 192 as well as different levels of this protein. Additional studies showed that mutations in the regulatory region of the PON1 gene contributed to the very different levels of plasma PON1 among individuals. It turned out that both the level of the enzyme as well as the amino acid present at position 192 (glutamine or arginine) are important in determining resistance to the active forms of specific organophosphorus insecticides, especially diazinon and chlorpyrifos. The position 192 amino acid also determined whether an individual's plasma hydrolyzed the nerve agents soman and sarin at high or low rates. It is not yet known whether these different rates of hydrolysis observed in biochemical assays reflect differences in sensitivity of individuals to nerve agents. Taken together, all of the experiments carried out to date indicate that engineered recombinant PON1 is an excellent candidate to use for treating cases of poisoning by specific organophosphorus compounds. The available data on the relationship of PON1 levels and position 192 genotype led us to introduce the term PON1 status to describe an individual's PON1 plasma level as well as their position 192 genotype.The characterization of the genetic variations of the PON1 gene together with experiments showing that HDL can protect the lipids in low density lipoprotein particles (LDL) from oxidation and that it was PON1 that was responsible for this protection have opened an entirely new area of investigation, the role of PON1 in protecting against vascular disease.More recent reports have noted that PON1 also metabolizes a number of drugs, activating some and inactivating others.This book describes the recent advances in understanding the role of PON1 in both cardiovascular disease and toxicology of insecticide exposure as well as some of the recent information indicating an important possible role in the pharmacokinetics of drug metabolism. The final chapter of the book provides an overview of the areas of PON1 research and suggests future directions for research on PON1 as well as the related, linked genes PON2 and PON3.
| Author | : Claus Jacob |
| Publisher | : Springer |
| Total Pages | : 476 |
| Release | : 2014-11-25 |
| Genre | : Medical |
| ISBN | : 9401789533 |
Nature endows us with a treasure chest of Green Gold full of amazing ‘redox-active’ substances which interfere with numerous biological processes in our own body, in animals, bacteria, fungi and plants. Whilst such natural products are all around and also in us, we still do not fully understand how these compounds actually work. This book attempts to resolve some of the mysteries and riddles associated with such products. Written by more than thirty international experts from academia and industry, it places a focus on modern developments in this field and considers such natural products from various angles, from their isolation and characterization all along to product development and commercialization. Throughout, the reader will be confronted with modern approaches which enable the efficient identification and isolation of new natural products, help to elucidate their mode(s) of action and permit practical uses in Medicine, Cosmetics, Agriculture, Industry and as functional foods.
| Author | : Mamadou Diouf |
| Publisher | : University of Michigan Press |
| Total Pages | : 278 |
| Release | : 2010-11-03 |
| Genre | : History |
| ISBN | : 0472070967 |
Collected essays exploring the origins and evolution of music and dance in Afro-Atlantic culture
| Author | : Lyle Campbell |
| Publisher | : MIT Press |
| Total Pages | : 478 |
| Release | : 2004 |
| Genre | : Language Arts & Disciplines |
| ISBN | : 9780262532679 |
This accessible, hands-on text not only introduces students to the important topicsin historical linguistics but also shows them how to apply the methods described and how to thinkabout the issues; abundant examples and exercises allow students to focus on how to do historicallinguistics. Distinctive to this text is its integration of the standard topics with others nowconsidered important to the field, including syntactic change, grammaticalization, sociolinguisticcontributions to linguistic change, distant genetic relationships, areal linguistics, and linguisticprehistory. Examples are taken from a broad range of languages; those from the more familiarEnglish, French, German, and Spanish make the topics more accessible, while those fromnon-Indo-European languages show the depth and range of the concepts they illustrate.This secondedition features expanded explanations and examples as well as updates in light of recent work inlinguistics, including a defense of the family tree model, a response to recent claims on lexicaldiffusion/frequency, and a section on why languages diversify and spread.
