Understanding Hydrogen Bonds
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Author | : Sławomir J Grabowski |
Publisher | : Royal Society of Chemistry |
Total Pages | : 487 |
Release | : 2020-11-13 |
Genre | : Science |
ISBN | : 183916042X |
Hydrogen bonded systems play an important role in all aspects of science but particularly chemistry and biology. Notably, the helical structure of DNA is heavily reliant on the hydrogens bonds between the DNA base pairs. Although the area of hydrogen bonding is one that is well established, our understanding has continued to develop as the power of both computational and experimental techniques has improved. Understanding Hydrogen Bonds presents an up-to-date overview of our theoretical and experimental understanding of the hydrogen bond. Well-established and novel approaches are discussed, including quantum theory of ‘atoms in molecules’ (QTAIM); the electron localization function (ELF) method and Car–Parinnello molecular dynamics; the natural bond orbital (NBO) approach; and X-ray and neutron diffraction and spectroscopy. The mechanism of hydrogen bond formation is described and comparisons are made between hydrogen bonds and other types of interaction. The author also takes a look at new types of interaction that may be classified as hydrogen bonds with a focus on those with multicentre proton acceptors or with multicentre proton donors. Understanding Hydrogen Bonds is a valuable reference for experimentalists and theoreticians interested in updating their understanding of the types of hydrogen bonds, their role in chemistry and biology, and how they can be studied.
Author | : Slawomir Grabowski |
Publisher | : Springer Science & Business Media |
Total Pages | : 536 |
Release | : 2006-10-07 |
Genre | : Science |
ISBN | : 140204853X |
This book uses examples from experimental studies to illustrate theoretical investigations, allowing greater understanding of hydrogen bonding phenomena. The most important topics in recent studies are covered. This volume is an invaluable resource that will be of particular interest to physical and theoretical chemists, spectroscopists, crystallographers and those involved with chemical physics.
Author | : George A. Jeffrey |
Publisher | : Springer Science & Business Media |
Total Pages | : 575 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 3642851355 |
Hydrogen bonds are weak attractions, with a binding strength less than one-tenth that of a normal covalent bond. However, hydrogen bonds are of extraordinary importance; without them all wooden structures would collapse, cement would crumble, oceans would vaporize, and all living things would disintegrate into random dispersions of inert matter. Hydrogen Bonding in Biological Structures is informative and eminently usable. It is, in a sense, a Rosetta stone that unlocks a wealth of information from the language of crystallography and makes it accessible to all scientists. (From a book review of Kenneth M. Harmon, Science 1992)
Author | : Gautam R. Desiraju |
Publisher | : International Union of Crystal |
Total Pages | : 530 |
Release | : 2001 |
Genre | : Hydrogen bonding |
ISBN | : 9780198509707 |
The weak or non-conventional hydrogen bond has been subject of intense scrutiny over recent years in several fields, in particular in structural chemistry, structural biology, and also in the pharmaceutical sciences. There is today a large body of experimental and theoretical evidenceconfirming that hydrogen bonds like C-H...O, N-H...pi, C-H...pi and even bonds like O-H...metal play distinctive roles in molecular recognition, guiding molecular association, and in determining molecular and supramolecular architectures. The relevant compound classes include organometalliccomplexes, organic and bio-organic systems, and also DNA and proteins. The book provides a comprehensive assessment of this interaction type, and is of interest to all those interested in structural and supramolecular science, including fields as crystal engineering and drug design.
Author | : Sławomir J. Grabowski |
Publisher | : MDPI |
Total Pages | : 323 |
Release | : 2018-09-27 |
Genre | : Science |
ISBN | : 3038422452 |
This book is a printed edition of the Special Issue "Analysis of Hydrogen Bonds in Crystals" that was published in Crystals
Author | : Ron Milo |
Publisher | : Garland Science |
Total Pages | : 400 |
Release | : 2015-12-07 |
Genre | : Science |
ISBN | : 1317230698 |
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Author | : George A. Jeffrey |
Publisher | : Oxford University Press on Demand |
Total Pages | : 303 |
Release | : 1997 |
Genre | : Fiction |
ISBN | : 9780195095494 |
This book is intended as an easy to read supplement to the often brief descriptions of hydrogen bonding found in most undergraduate chemistry and molecular biology textbooks. It describes and discusses current ideas concerning hydrogen bonds ranging from the very strong to the very weak, with introductions to the experimental and theoretical methods involved.
Author | : Gastone Gilli |
Publisher | : OUP Oxford |
Total Pages | : 330 |
Release | : 2009-06-25 |
Genre | : Science |
ISBN | : 0191580279 |
Hydrogen bond (H-bond) effects are known: it makes sea water liquid, joins cellulose microfibrils in trees, shapes DNA into genes and polypeptide chains into wool, hair, muscles or enzymes. Its true nature is less known and we may still wonder why O-H...O bond energies range from less than 1 to more than 30 kcal/mol without apparent reason. This H-bond puzzle is re-examined here from its very beginning and presented as an inclusive compilation of experimental H-bond energies and geometries. New concepts emerge from this analysis: new classes of systematically strong H-bonds (CAHBs and RAHBs: charge- and resonance-assisted H-bonds); full H-bond classification in six classes (the six chemical leitmotifs); and assessment of the covalent nature of strong H-bonds. This leads to three distinct but inter-consistent models able to rationalize the H-bond and predict its strength, based on classical VB theory, matching of donor-acceptor acid-base parameters (PA or pKa), or shape of the H-bond proton-transfer pathway. Applications survey a number of systems where strong H-bonds play an important functional role, namely drug-receptor binding, enzymatic catalysis, ion-transport through cell membranes, crystal design and molecular mechanisms of functional materials.
Author | : Giuliano Preparata |
Publisher | : World Scientific |
Total Pages | : 264 |
Release | : 1995 |
Genre | : Science |
ISBN | : 9789810222499 |
Up until now the dominant view of condensed matter physics has been that of an ?electrostatic MECCANO? (erector set, for Americans). This book is the first systematic attempt to consider the full quantum-electrodynamical interaction (QED), thus greatly enriching the possible dynamical mechanisms that operate in the construction of the wonderful variety of condensed matter systems, including life itself.A new paradigm is emerging, replacing the ?electrostatic MECCANO? with an ?electrodynamic NETWORK,? which builds condensed matter through the long range (as opposed to the ?short range? nature of the usual electrostatic forces) electrodynamical interaction; this interaction creates ?coherent configurations? of the elementary systems (atoms and molecules), which oscillate in phase with a coherent macroscopic (and classical) electromagnetic field that, through the strong interaction with matter, remains trapped inside it.
Author | : A. S. Marfunin |
Publisher | : Springer Science & Business Media |
Total Pages | : 570 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 3642785239 |
All existing introductory reviews of mineralogy are written accord ing to the same algorithm, sometimes called the "Dana System of Mineralogy". Even modern advanced handbooks, which are cer tainly necessary, include basic data on minerals and are essentially descriptive. When basic information on the chemistry, structure, optical and physical properties, distinguished features and para genesis of 200-400 minerals is presented, then there is practically no further space available to include new ideas and concepts based on recent mineral studies. A possible solution to this dilemma would be to present a book beginning where introductory textbooks end for those already famil iar with the elementary concepts. Such a volume would be tailored to specialists in all fields of science and industry, interested in the most recent results in mineralogy. This approach may be called Advanced Mineralogy. Here, an attempt has been made to survey the current possibilities and aims in mineral matter investigations, including the main characteristics of all the methods, the most important problems and topics of mineral ogy, and related studies. The individual volumes are composed of short, condensed chap ters. Each chapter presents in a complete, albeit condensed, form specific problems, methods, theories, and directions of investigations, and estimates their importance and strategic position in science and industry.