Translational Orthopedics
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| Author | : Jeffrey A. Bakal |
| Publisher | : Elsevier |
| Total Pages | : 580 |
| Release | : 2024-04-15 |
| Genre | : Science |
| ISBN | : 0323885624 |
Translational Orthopedics: Designing and Conducting Translational Research covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. The reader will come to fully understand important concepts including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in translational orthopedics, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in translational orthopedics, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every Medical Researcher or Orthopedist who has ever had a good clinical idea but not the knowledge of how to test it. - Focuses on the principles of evidence-based medicine and applies these principles to the design of translational investigations within orthopedics - Provides a practical, straightforward approach that helps investigators navigate challenging considerations in study design and implementation - Details discussions of the critical appraisal of published studies in translational orthopedics, supporting evaluation with respect to measuring outcomes and making effective use of all types of evidence in patient care
| Author | : Daniel J. Berry |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 476 |
| Release | : 2007 |
| Genre | : Medical |
| ISBN | : 9780781796385 |
Written by leading experts from the Mayo Clinic, this volume of our Orthopaedic Surgery Essentials Series presents all the information residents need on hip, knee, shoulder, and elbow reconstruction in adults. It can easily be read cover to cover during a rotation or used for quick reference before a patient workup or operation. The user-friendly, visually stimulating format features ample illustrations, algorithms, bulleted lists, charts, and tables. Coverage of each region includes physical evaluation and imaging, evaluation and treatment of disorders, and operative treatment methods. The extensive coverage of operative treatment includes primary and revision arthroplasty and alternatives to arthroplasty.
| Author | : Lei Yang |
| Publisher | : Academic Press |
| Total Pages | : 364 |
| Release | : 2018-11-30 |
| Genre | : Technology & Engineering |
| ISBN | : 012813478X |
Biomaterials in Translational Medicine delivers timely and detailed information on the latest advances in biomaterials and their role and impact in translational medicine. Key topics addressed include the properties and functions of these materials and how they might be applied for clinical diagnosis and treatment. Particular emphasis is placed on basic fundamentals, biomaterial formulations, design principles, fabrication techniques and transitioning bench-to-bed clinical applications. The book is an essential reference resource for researchers, clinicians, materials scientists, engineers and anyone involved in the future development of innovative biomaterials that drive advancement in translational medicine. - Systematically introduces the fundamental principles, rationales and methodologies of creating or improving biomaterials in the context of translational medicine - Includes the translational or commercialization status of these new biomaterials - Provides the reader with enough background knowledge for a fundamental grip of the difficulties and technicalities of using biomaterial translational medicine - Directs the reader on how to find other up-to-date sources (i.e. peer reviewed journals) in the field of translational medicine and biomaterials
| Author | : Dustin L. Williams |
| Publisher | : Springer Nature |
| Total Pages | : 170 |
| Release | : 2019-11-06 |
| Genre | : Medical |
| ISBN | : 3030306674 |
This book offers a much-needed discussion on the targeting of biofilm-related infections. Chapters include discussions on the impact of biofilm on medical implants, industrial applications, as well as wound and tissue infections. It also offers discussions on regulatory management for industrial sectors and medical environments. Given that there continues to be a paucity of effective antimicrobial products, devices, and coatings in clinical and industrial use that effectively reduce rates of infection or biofilm-related problems, Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors, offers a fresh and much-needed perspective aimed at helping create healthier controlled environments and safer devices. This comprehensive book is indispensable for industrial and academic translational researchers, device developers, and regulatory experts looking to create more effective antimicrobial products.
| Author | : Pantea Keikhosrokiani |
| Publisher | : Academic Press |
| Total Pages | : 356 |
| Release | : 2022-05-19 |
| Genre | : Medical |
| ISBN | : 0323985165 |
Big Data Analytics and Medical Information Systems presents the valuable use of artificial intelligence and big data analytics in healthcare and medical sciences. It focuses on theories, methods and approaches in which data analytic techniques can be used to examine medical data to provide a meaningful pattern for classification, diagnosis, treatment, and prediction of diseases. The book discusses topics such as theories and concepts of the field, and how big medical data mining techniques and applications can be applied to classification, diagnosis, treatment, and prediction of diseases. In addition, it covers social, behavioral, and medical fake news analytics to prevent medical misinformation and myths. It is a valuable resource for graduate students, researchers and members of biomedical field who are interested in learning more about analytic tools to support their work. - Presents theories, methods and approaches in which data analytic techniques are used for medical data - Brings practical information on how to use big data for classification, diagnosis, treatment, and prediction of diseases - Discusses social, behavioral, and medical fake news analytics for medical information systems
| Author | : Leesa M Galatz |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 1567 |
| Release | : 2023-01-18 |
| Genre | : Medical |
| ISBN | : 1975197488 |
Orthopaedic Knowledge Update® 14, edited by Leesa M. Galatz, MD, MBA, FAAOS, and Frederick M. Azar, MD, FAAOS, brings you a comprehensive synthesis of the latest clinical thinking and best practices across all orthopaedic specialty areas. OKU® 14 covers developments of the last three years with revisions and updates based on new evidence, outcomes, and innovations in the recent literature, including annotated references. Keep pace with the rapidly evolving body of orthopaedic knowledge and clinical practice with OKU’s objective, balanced coverage. Backed by clinical research, informed by practical experience, and rigorously edited by thought leaders across the orthopaedic specialties, OKU®14 is your most up-to-date resource to guide your delivery of high-quality orthopaedic patient care today.
| Author | : Frederick M Azar |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : |
| Release | : 2019-05-15 |
| Genre | : Medical |
| ISBN | : 0323682588 |
Guest edited by Drs. Jonathan Kay and Sergio Schwartzman, this issue of Rheumatic Disease Clinics will cover Controversies in Rheumatology. This issue is one of four selected each year by our series Consulting Editor, Dr. Michael Weisman of Cedars-Sinai. Articles explore several questions, including, but not limited to: Is triple therapy or methotrexate plus a biologic the initial treatment of choice for RA patients; Is hypo or hyper-uricemia a risk requiring treatment for cardiac morbidity and mortality; Are there benefits and risks to biosimilars from a patient perspective; Should platelet-rich plasma be used to treat osteoarthritis; Is there a role for stem cell therapy to treat cartilage defects in osteoarthritis; Should any rheumatology patient, today, be treated with bone marrow ablation and stem cell transplantation; Is there effective prevention, prophylaxis, or treatment for CPPD arthritis; Is fibromyalgia a psychiatric disease or a pain syndrome; Should cyclophosphamide still be used to treat ANCA-associated vasculitis; Does methotrexate have a place in the treatment of psoriatic arthritis; Should hydroxychloroquine dosing be limited because of potential ocular toxicity; and Should generalized immunosuppression or targeted organ treatment be the best principle for overall management of SLE.
| Author | : Dominique G. Poitout |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 694 |
| Release | : 2004-07-02 |
| Genre | : Medical |
| ISBN | : 9781852334819 |
Current clinical orthopedic practice requires practitioners to have extensive knowledge of a wide range of disciplines from molecular biology to bioengineering and from the application of new methods to the evaluation of outcome. The biomechanics of and biomaterials used in orthopedics have become increasingly important as the possibilities have increased to treat patients with foreign material introduced both as optimized osteosynthesis after trauma and as arthroplasties for joint diseases, sequelae of trauma or for tumor treatment. Furthermore, biomaterial substitutes are constantly being developed to replace missing tissue. Biomechanics and Biomaterials in Orthopedics provides an important update within this highly important field. Professor Dominique Poitout has collected a series of high-quality chapters by globally renowned researchers and clinicians. Under the auspices of the International Society of Orthopaedic Surgery and Traumatology (SICOT) and International Society of Orthopaedic and Traumatology Research (SIROT), this book now provides permanent and specific access to the considerable international knowledge in the field of locomotor system trauma and disease treatment using the novel bioengineering solutions. This book covers both basic concepts concerning biomaterials and biomechanics as well as their clinical application and the experience from everyday practical use. This book will be of great value to specialists in orthopedics and traumatology, while also provide an important basis for graduate and postgraduate learning.
| Author | : Beth A. Winkelstein |
| Publisher | : CRC Press |
| Total Pages | : 637 |
| Release | : 2012-12-18 |
| Genre | : Medical |
| ISBN | : 1439860947 |
Given the strong current attention of orthopaedic, biomechanical, and biomedical engineering research on translational capabilities for the diagnosis, prevention, and treatment of clinical disease states, the need for reviews of the state-of-art and current needs in orthopaedics is very timely. Orthopaedic Biomechanics provides an in-depth review o
| Author | : Lei Yang |
| Publisher | : Woodhead Publishing |
| Total Pages | : 218 |
| Release | : 2015-07-28 |
| Genre | : Medical |
| ISBN | : 0857098500 |
Nanotechnology-Enhanced Orthopedic Materials provides the latest information on the emergence and rapid development of nanotechnology and the ways it has impacted almost every aspect of biomedical engineering. This book provides readers with a comprehensive overview of the field, focusing on the fabrication and applications of these materials, presenting updated, practical, and systematic knowledge on the synthesis, processing, and modification of nanomaterials, along with the rationale and methodology of applying such materials for orthopedic purposes. Topics covered include a wide range of orthopedic material formulations, such as ceramics, metals, polymers, biomolecules, and self-assemblies. Final sections explore applications and future trends in nanotechnology-enhanced orthopedic materials. - Details practical information on the fabrication and modification of new and traditional orthopedic materials - Analyzes a wide range of materials, designs, and applications of nanotechnology for orthopedics - Investigates future trends in the field, including sections on orthopedic materials with bacterial-inhibitory properties and novel materials for the control of immune and inflammatory responses
