Toxicological Chemistry Second Edition
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| Author | : Stanley E. Manahan |
| Publisher | : CRC Press |
| Total Pages | : 466 |
| Release | : 1992-03-17 |
| Genre | : Science |
| ISBN | : 9780873716215 |
Toxicological Chemistry, 2nd Edition provides an easy-to-understand general discussion of biological processes operating on environmental chemical species. It also focuses on the chemistry of toxic substances based on their interactions with biological tissue and living organisms. The book is designed to appeal to readers with diverse general backgrounds. It assumes only a minimal background in chemistry and none in biology or microbiology. Introductory material regarding these fields is presented in the first few chapters so that more sophisticated topics can be addressed throughout the remainder of the book. Detailed discussions about specific areas of research are avoided, although key references on major topics are provided for readers who require more in-depth information. Toxicological Chemistry, 2nd Edition is useful for anyone concerned with the biological fate and effects of chemicals. It is ideal as a general reference book, source of background material, or textbook for regulatory personnel, students, engineers with consulting firms, health and safety personnel, and others.
| Author | : Stanley E. Manahan |
| Publisher | : CRC Press |
| Total Pages | : 1024 |
| Release | : 2000-07-31 |
| Genre | : Science |
| ISBN | : 9781566704915 |
Written by a leader in the field, the Fundamentals of Environmental Chemistry, Second Edition puts the fundamentals of chemistry and environmental chemistry right at your students fingertips. Manahan presents the material in an understandable and interesting manner without being overly simplistic. They get basic coverage on: - Matter and the basis of its physical nature and behavior - Organic and biological chemistry - Chemistry of water, soil, and air - Industrial chemistry - Toxicological chemistry as it pertains to occupational health and human exposure to pollutants and toxicants - Energy, nuclear energy, and nuclear waste - Applications of nuclear science in areas such as tracing pesticide degradation and nuclear medicine - More than an introduction to this field, Fundamentals of Environmental Chemistry, Second Edition provides the foundation that gives your students an understanding of the chemical processes of the environment and the effects pollution on those processes.
| Author | : Brian J. Lukey |
| Publisher | : CRC Press |
| Total Pages | : 752 |
| Release | : 2007-12-17 |
| Genre | : Medical |
| ISBN | : 1420046624 |
The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was published just prior to the terrorist attacks of September 11th, 2001. Reflecting a greater sense of urgency within the field of chemical defense since this event, research related to chemical warfare agents (CWAs) continues to expand at a remarkable pace.
| Author | : Hugh MacPherson |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 288 |
| Release | : 2007-10-12 |
| Genre | : Medical |
| ISBN | : 0443100292 |
This is the first book to set out a full range of research strategies for evaluating the clinical practice of acupuncture. Leading acupuncturists and researchers with international reputations share their expertise. They illustrate their descriptions with practical examples of what has worked and what has not. It outlines many of the key challenges in the field. These challenges relate to the nature of acupuncture and the gap between current research evidence and the actual experiences of acupuncturists in the field. By focusing the chapters on key research questions, rather than methods, the book has a user-friendly feel. Each chapter is easily accessible with brief explanations of research designs as well as vignettes of relevant past research. The book is based on a deep understanding of acupuncture, with its inherent complexity in practice, whether based on traditional principles or more modern concepts. By incorporating a more sophisticated understanding of the field, this book details a range of strategies aiming to develop the evidence base with the utmost rigour. It is the first book on acupuncture research to take this unique view, integrating the very best of evidence-based medicine with a genuine sensitivity to the discipline of acupuncture, from its traditional and holistic roots to its more modern interpretations.
| Author | : Donald G. Crosby |
| Publisher | : Oxford University Press on Demand |
| Total Pages | : 336 |
| Release | : 1998 |
| Genre | : Medical |
| ISBN | : 9780195117134 |
Although they are two aspects of the same subject, environmental toxicology and environmental chemistry are usually presented as though they are entirely separate from one another; even their practitioners often seem unaware of the connections. Environmental Toxicology and Chemistry is the first text to tie these subjects closely together, demonstrating the immediate relevance of each subject to the other while also providing basic, easily understandable introductions to both areas. This unique work presents their principles and applications through numerous illustrative examples and special topics that highlight current environmental concerns. It provides up-to-date as well as historical examples of both subjects and includes discussions of ecotoxicology, epidemiology, predictive methods, and other topics not covered in similar texts. It also includes invertebrates and nonmammal vertebrates, plants, and microorganisms, as well as humans and other mammals. The first five chapters place chemicals in the environment; the following five provide the biological and toxicological settings; and the remaining six chapters offer examples of specific chemicals, their toxic effects and significance, and predictions of fate and toxicity. Each chapter concludes with a discussion of a related topic of particular public and scientific interest, such as chemical carcinogens, pesticide residues, or hazardous wastes. Ideal for advanced undergraduate and graduate students in environmental toxicology courses, Environmental Toxicology and Chemistry offers a timely, comprehensive introduction to the principles of toxicology as they apply to our environment. It is also useful for professionals and practitioners in a wide range of environmentally related fields and businesses.
| Author | : Barry Levine |
| Publisher | : Amer. Assoc. for Clinical Chemistry |
| Total Pages | : 406 |
| Release | : 2003 |
| Genre | : Law |
| ISBN | : 9781890883874 |
| Author | : Stanley E. Manahan |
| Publisher | : CRC Press |
| Total Pages | : 396 |
| Release | : 1990-07-02 |
| Genre | : Technology & Engineering |
| ISBN | : 9780873712095 |
The first of its kind, this new book takes a unique look at hazardous wastes. Designed in a compact form, it is an easy-to-understand book on the chemistry and toxicology of hazardous substances and wastes. It begins with a basic coverage of chemistry and biochemistry, environmental chemical processes, and toxicology. Detailed chapters discuss the chemistry and toxicology of inorganic and organic hazardous substances and biohazards. The fully documented text explains procedures for eliminating, detoxifying, and disposing of hazardous wastes with continual reference to their basic chemistry and toxicology. Hazardous Waste Chemistry, Toxicology, and Treatment is an indispensable reference guide for everyone involved with hazardous substances, wastes, toxicology, and basic chemistry, organic chemistry, and biochemistry. This title is an ideal textbook for senior and graduate level courses studying hazardous substances, hazardous wastes, and industrial hygiene.
| Author | : Frank A Barile |
| Publisher | : CRC Press |
| Total Pages | : 368 |
| Release | : 2013-04-02 |
| Genre | : Medical |
| ISBN | : 1842145282 |
Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, including absorption, distribution, metabolism, and elimination of toxins, including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition, the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing, such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies, including dermal, ocular, and reproductive toxicity testing. In addition, mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity, target organ toxicity, and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications, the concepts of standardization and validation of in vitro techniques (especially large, organized validation efforts currently supported by US and EU regulatory agencies), and the theories supporting the development of in vitro methodologies. This second edition is a must-read for undergraduate and graduate toxicology students. Industrial and academic research centers will also find the text useful for establishing a toxicology testing laboratory.
| Author | : Harold Zeliger |
| Publisher | : William Andrew |
| Total Pages | : 575 |
| Release | : 2011-06-24 |
| Genre | : Medical |
| ISBN | : 1437734642 |
In this important reference work, Zeliger catalogs the known effects of chemical mixtures on the human body and also proposes a framework for understanding and predicting their actions in terms of lipophile (fat soluble) / hydrophile (water soluble) interactions. The author's focus is on illnesses that ensue following exposures to mixtures of chemicals that cannot be attributed to any one component of the mixture. In the first part the mechanisms of chemical absorption at a molecular and macromolecular level are explained, as well as the body's methods of defending itself against xenobiotic intrusion. Part II examines the sources of the chemicals discusssed, looking at air and water pollution, food additives, pharmaceuticals, etc. Part III, which includes numerous case studies, examines specific effects of particular mixtures on particular body systems and organs and presents a theoretical framework for predicting what the effects of uncharacterized mixtures might be. Part IV covers regulatory requirements and the need to adjust recommended exposure levels for products containing mixtures. It also contains recommendations on how to limit exposure to mixtures in the products we use and on how to limit release of mixtures into the environment. Providing brief summaries of each mixture and its effects, Zeliger provides a comprehensive reference, a jumping off point for professionals (with extensive chapter bibliographies) and an introduction to the topic for those studying traditional toxicology. Addressing many inadequately understood illnesses and conditions such as asthma, infertility and cancer, it will also be of interest to health professionals, environmental scientists and lawyers. - Presents a theoretical framework for predicting the effects of chemical mixtures for which no specific data exists (this predictive aspect is important due to the vast number of different potential chemical combinations – far too many to comprehensively catalog) - A quick and convenient source of hard to come by data on the rapidly developing field of chemical mixtures, for groups including chemists and engineers, toxicologists, health professionals and environmental scientists - New and updated material comprises over 30% of this timely new edition, which includes the latest research data alongside an expanded introduction to the science and art of predicting the toxicological properties of chemical mixtures
| Author | : Franz Worek |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 346 |
| Release | : 2016-05-17 |
| Genre | : History |
| ISBN | : 1782628037 |
This book provides an up-to-date treatise on the on-going research into the toxicology of chemical warfare agents, the diagnosis and verification of exposure, and the pre- and post-exposure treatment of poisoning.
