Environmental Neurotoxicology

Environmental Neurotoxicology
Author: National Research Council
Publisher: National Academies Press
Total Pages: 167
Release: 1992-02-01
Genre: Science
ISBN: 0309045312

Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.

Toxic Effects of Mercury

Toxic Effects of Mercury
Author: Shabnum Nabi
Publisher: Springer
Total Pages: 265
Release: 2014-07-25
Genre: Science
ISBN: 8132219228

Mercury is widespread in our environment. Methylmercury, an organic form of mercury, can accumulate in the aquatic food chain and lead to high concentrations in predatory fish. When consumed by humans, contaminated fish represent a public health risk. Toxic Effects of Mercury intends to facilitate among its readers the understanding of the importance of mercury pollution in the environment and the health consequences associated with exposure to this metal. The knowledge on methylmercury (MeHg) toxicity collected over the years is undoubtedly robust creating an impression all that is to be learnt about this metal has already been accomplished. However, in large measure, past knowledge has merely laid the ground for interesting questions that have yet to be fully addressed and concepts have yet to be deciphered. One of my major goals was to make a valiant attempt to include state-of-the-art information on the mechanisms of mercury toxicity, describing its effects on cultured cellular systems as well as in whole living organisms, starting from the lessons learned from the tragic events in Minamata Bay, Japan. A special focus of the book is on the neurotoxic effects of MeHg. An understanding at the cellular level is necessary to gather information on the structural and functional alterations induced by MeHg and how they possibly become unmasked and evident at the behavioral level, 32 chapters of the book have been organised having these considerations in mind. This book will provide state-of-the-art information to the graduate students training in toxicology, risk assessors, researchers and medical providers at large. It is aimed to bring the readers updated information on contemporary issues associated with exposure to methylmercury, from its effects on stem cells and neurons to population studies. It is a valuable resource for individuals interested in the public health effects and regulation of mercury. The report provides an excellent example of the implications of decisions in the risk assessment process for a larger audience and is written with the hope that the information will provide better understanding of the mercury problems which confront us.

Toxic Effects

Toxic Effects
Author: Joel Shulkin
Publisher: Blackstone Publishing
Total Pages: 305
Release: 2022-09-20
Genre: Fiction
ISBN: 1094024023

Don’t forget to be afraid. Neuropsychiatrist Cristina Silva cannot escape her past. The voice in her head of her former identity won’t let her. Cristina also can’t quite manage to force herself to forget the ex-boyfriend she dumped: handsome police detective Gary Wilson. Soon after beginning her new job at the Longwood Memory Center, Cristina receives a startling phone call from her contact at the FBI: an assassin is crisscrossing the country, killing anyone connected to the now-defunct pharmaceutical company ReMind—people like Cristina. The shadowy criminal enterprise Zero Dark is back. Indeed, an assassin is tracking Cristina, a literal femme fatale known as Dama Branca. Like Cristina, DB’s memory was robbed by Zero Dark. Transfixed by the brilliant doctor, DB’s unsure what’s preventing her from killing Cristina. DB has memory glitches and longs to interpret them. Whether or not these have to do with Cristina, she doesn’t know, but she senses their fates are entwined—with any luck, not fatally. Danger lurks in the shadows. Cristina’s spurned lover, Wilson, is investigating the suspicious deaths of local teens, convinced they’re not accidents. Before their bewildering ends, all the victims exhibit bizarre behavior, and there are now terrified whispers among their friends of a hooded boogeyman called Sack Man. One exceptional young man, Reggie Horne, is clearly in the middle of this bedlam. Wilson vows to prevent Sack Man from claiming Reggie as his next casualty. And when Cristina’s in danger, Wilson is never far away. Just as it becomes apparent their two stories are entangled, the peril shoots sky-high. With at least one killer in their wake, they must quickly determine what’s real and what’s not. Unlocking Cristina’s memories could save many lives—her own included.

Prudent Practices in the Laboratory

Prudent Practices in the Laboratory
Author: National Research Council
Publisher: National Academies Press
Total Pages: 360
Release: 2011-03-25
Genre: Science
ISBN: 0309211581

Prudent Practices in the Laboratory-the book that has served for decades as the standard for chemical laboratory safety practice-now features updates and new topics. This revised edition has an expanded chapter on chemical management and delves into new areas, such as nanotechnology, laboratory security, and emergency planning. Developed by experts from academia and industry, with specialties in such areas as chemical sciences, pollution prevention, and laboratory safety, Prudent Practices in the Laboratory provides guidance on planning procedures for the handling, storage, and disposal of chemicals. The book offers prudent practices designed to promote safety and includes practical information on assessing hazards, managing chemicals, disposing of wastes, and more. Prudent Practices in the Laboratory will continue to serve as the leading source of chemical safety guidelines for people working with laboratory chemicals: research chemists, technicians, safety officers, educators, and students.

Waste Incineration and Public Health

Waste Incineration and Public Health
Author: National Research Council
Publisher: National Academies Press
Total Pages: 336
Release: 2000-10-21
Genre: Science
ISBN: 030906371X

Incineration has been used widely for waste disposal, including household, hazardous, and medical wasteâ€"but there is increasing public concern over the benefits of combusting the waste versus the health risk from pollutants emitted during combustion. Waste Incineration and Public Health informs the emerging debate with the most up-to-date information available on incineration, pollution, and human healthâ€"along with expert conclusions and recommendations for further research and improvement of such areas as risk communication. The committee provides details on: Processes involved in incineration and how contaminants are released. Environmental dynamics of contaminants and routes of human exposure. Tools and approaches for assessing possible human health effects. Scientific concerns pertinent to future regulatory actions. The book also examines some of the social, psychological, and economic factors that affect the communities where incineration takes place and addresses the problem of uncertainty and variation in predicting the health effects of incineration processes.

Improving Public Health Through Mycotoxin Control

Improving Public Health Through Mycotoxin Control
Author: International Agency for Research on Cancer
Publisher: IARC Scientific Publications
Total Pages: 0
Release: 2012
Genre: Medical
ISBN: 9789283221586

Mycotoxins are fungal toxins that contaminate many of the most frequently consumed foods and feeds worldwide, including staple foods consumed by many of the poorest and most vulnerable populations in the world. Therefore, human and animal exposure to one or more of this broad group of toxins is widespread. Mycotoxins have the potential to contribute to a diversity of adverse health effects in humans, including cancer, even at low concentrations. Economic burdens resulting from crop contamination are added to those on health. Given the ubiquitous nature of exposure in many countries, an urgent need exists for a coordinated international response to the problem of mycotoxin contamination of food. This book aims to sensitize the international community to the mycotoxin problem in a format that is accessible to a wide audience and is useful to decision-makers across a broad spectrum of disciplines, including agriculture, public health, marketing, and economics. The editors hope that this book will be a stimulus to governments, nongovernmental and international organizations, and the private sector to initiate measures designed to minimize mycotoxin exposure in high-risk populations. The book not only provides a scientific description of the occurrence and effects of mycotoxins but also goes further by outlining approaches to reduce mycotoxin exposure aimed at improving public health in low-income countries.

Toxicological Effects of Methylmercury

Toxicological Effects of Methylmercury
Author: National Research Council
Publisher: National Academies Press
Total Pages: 364
Release: 2000-09-27
Genre: Nature
ISBN: 0309171717

Mercury is widespread in our environment. Methylmercury, one organic form of mercury, can accumulate up the aquatic food chain and lead to high concentrations in predatory fish. When consumed by humans, contaminated fish represent a public health risk. Combustion processes, especially coal-fired power plants, are major sources of mercury contamination in the environment. The U.S. Environmental Protection Agency (EPA) is considering regulating mercury emissions from those plants. Toxicological Effects of Methylmercury reviews the health effects of methylmercury and discusses the estimation of mercury exposure from measured biomarkers, how differences between individuals affect mercury toxicity, and appropriate statistical methods for analysis of the data and thoroughly compares the epidemiological studies available on methylmercury. Included are discussions of current mercury levels on public health and a delineation of the scientific aspects and policy decisions involved in the regulation of mercury. This report is a valuable resource for individuals interested in the public health effects and regulation of mercury. The report also provides an excellent example of the implications of decisions in the risk assessment process for a larger audience.

Damp Indoor Spaces and Health

Damp Indoor Spaces and Health
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 369
Release: 2004-10-01
Genre: Science
ISBN: 0309091934

Almost all homes, apartments, and commercial buildings will experience leaks, flooding, or other forms of excessive indoor dampness at some point. Not only is excessive dampness a health problem by itself, it also contributes to several other potentially problematic types of situations. Molds and other microbial agents favor damp indoor environments, and excess moisture may initiate the release of chemical emissions from damaged building materials and furnishings. This new book from the Institute of Medicine examines the health impact of exposures resulting from damp indoor environments and offers recommendations for public health interventions. Damp Indoor Spaces and Health covers a broad range of topics. The book not only examines the relationship between damp or moldy indoor environments and adverse health outcomes but also discusses how and where buildings get wet, how dampness influences microbial growth and chemical emissions, ways to prevent and remediate dampness, and elements of a public health response to the issues. A comprehensive literature review finds sufficient evidence of an association between damp indoor environments and some upper respiratory tract symptoms, coughing, wheezing, and asthma symptoms in sensitized persons. This important book will be of interest to a wide-ranging audience of science, health, engineering, and building professionals, government officials, and members of the public.

Monitoring Human Tissues for Toxic Substances

Monitoring Human Tissues for Toxic Substances
Author: National Research Council
Publisher: National Academies Press
Total Pages: 224
Release: 1991-02-01
Genre: Science
ISBN: 0309044375

The National Human Monitoring Program (NHMP) identifies concentrations of specific chemicals in human tissues, including toxicologic testing and risk assessment determinations. This volume evaluates the current activities of the NHMP; identifies important scientific, technical, and programmatic issues; and makes recommendations regarding the design of the program and use of its products.