Topical Nail Products and Ungual Drug Delivery

Topical Nail Products and Ungual Drug Delivery
Author: S Narasimha Murthy
Publisher: CRC Press
Total Pages: 293
Release: 2012-09-26
Genre: Medical
ISBN: 1439811318

Discussing existing techniques, ongoing research, new approaches, and basic concepts in the treatment of nail diseases, Topical Nail Products and Ungual Drug Delivery summarizes the current knowledge and represents a jumping-off point for creating novel techniques of drug delivery across the nail.A growing area of pharmaceutical research, the searc

Topical Nail Products and Ungual Drug Delivery

Topical Nail Products and Ungual Drug Delivery
Author: S Narasimha Murthy
Publisher: CRC Press
Total Pages: 303
Release: 2012-09-26
Genre: Medical
ISBN: 1439811296

Discussing existing techniques, ongoing research, new approaches, and basic concepts in the treatment of nail diseases, Topical Nail Products and Ungual Drug Delivery summarizes the current knowledge and represents a jumping-off point for creating novel techniques of drug delivery across the nail. A growing area of pharmaceutical research, the search for efficient delivery techniques that can cross the nail barrier has yielded several effective strategies, brought together in this book. Topics Include Nail anatomy, physiology, diseases, and treatment Permeability of the nail plate Topical nail formulations Approaches to enhance ungual and trans-ungual drug delivery In vitro and in vivo models to evaluate topical nail formulations Nail sampling techniques Bioengineering of the nail Trans-ungual iontophoresis Pharmacokinetics of drugs in the nail apparatus Onychopharmacokinetics: proposed model insight Photodynamic therapy of nail diseases The nail as a surrogate for investigating drug use

Percutaneous Absorption

Percutaneous Absorption
Author: Robert L. Bronaugh
Publisher: CRC Press
Total Pages: 992
Release: 1999-05-28
Genre: Science
ISBN: 9781420000948

Since publication of the Second Edition in 1989, numerous innovations have occurred that affect the way scientists look at issues in the field of percutaneous absorption. Focusing on recent advances as well as updating and expanding the scope of topics covered in the previous edition, Percutaneous Absorption, Third Edition provides thorough coverage of the skin's role as an important portal of entry for chemicals into the body. Assembles the work of nearly 80 experts-30 more than the Second Edition-into a unified, comprehensive volume that contains the latest ideas and research! Complete with nearly 600 drawings, photographs, equations, and tables and more than 1600 bibliographic citations of pertinent literature, Percutaneous Absorption, Third Edition details the applied biology of percutaneous penetration factors that affect skin permeation, such as age, vehicles, metabolism, hydration of skin, and chemical structure in vivo and in vitro techniques for measuring absorption, examining factors influencing methodology such as animal models, volatility of test compound, multiple dosage, and artificial membranes procedures for use in transdermal delivery, exploring topics such as effects of penetration enhancers on absorption, optimizing absorption, and the topical delivery of drugs to muscle tissue And presents new chapters on mathematical models cutaneous metabolism prediction of percutaneous absorption in vitro absorption methodology dermal decontamination concentration of chemicals in skin transdermal drug delivery mechanisms of absorption safety evaluation of cosmetics absorption of drugs and cosmetic ingredients nail penetration Emphasizes human applications-particularly useful for pharmacists, pharmacologists, dermatologists, cosmetic scientists, biochemists, toxicologists, public health officials, manufacturers of cosmetic and toiletry products, and graduate students in these disciplines! An invaluable reference source for readers who need to keep up with the latest developments in the field, Percutaneous Absorption, Third Edition is also an excellent experimental guide for laboratory personnel.

Focal Controlled Drug Delivery

Focal Controlled Drug Delivery
Author: Abraham J. Domb
Publisher: Springer Science & Business Media
Total Pages: 700
Release: 2014-02-17
Genre: Medical
ISBN: 1461494346

The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ.

Onychomycosis

Onychomycosis
Author: Dimitris Rigopoulos
Publisher: John Wiley & Sons
Total Pages: 243
Release: 2018-08-06
Genre: Medical
ISBN: 1119226538

The definitive guide to one of the world’s most prevalent dermatologic conditions Onychomycosis is a fungal nail disease that accounts for 40% of all nail disorders, affecting 1 out of 10 people at some stage in their lives. Compiled by leading dermatologists with expert knowledge of the condition, Onychomycosis: Diagnosis and Effective Management provides a clear and clinically focused reference tool for those looking to treat patients expediently and successfully. This in-depth guide covers all aspects of disease management, from differential diagnosis and lab analysis to topical and systemic treatments. Designed to be a functional and accessible resource, the text also highlights key learning points, with real-life case studies and helpful take-home messages included in each chapter. Coverage of recent innovations and cutting-edge methods ensure the content is relevant to today’s dermatologists, while thorough explanations of routine techniques, prognostic factors, and epidemiology make this is an excellent handbook for anyone studying the disease for the first time. The book features: A complete guide to the diagnosis and treatment of this common disorder Key learning points, case studies, and take-home messages to aid quick and easy consultation Insights from world-renowned dermatological experts from North America and Europe Over 70 illustrations Onychomycosis is a reliable, easy-to-use companion for trainees and experienced specialists alike, and an invaluable asset to any clinic treating nail conditions.

Cosmetic Formulation

Cosmetic Formulation
Author: Heather A.E. Benson
Publisher: CRC Press
Total Pages: 479
Release: 2019-04-05
Genre: Medical
ISBN: 1482235404

Cosmetics are the most widely applied products to the skin and include creams, lotions, gels and sprays. Their formulation, design and manufacturing ranges from large cosmetic houses to small private companies. This book covers the current science in the formulations of cosmetics applied to the skin. It includes basic formulation, skin science, advanced formulation, and cosmetic product development, including both descriptive and mechanistic content with an emphasis on practical aspects. Key Features: Covers cosmetic products/formulation from theory to practice Includes case studies to illustrate real-life formulation development and problem solving Offers a practical, user-friendly approach, relying on the work of recognized experts in the field Provides insights into the future directions in cosmetic product development Presents basic formulation, skin science, advanced formulation and cosmetic product development

Baran and Dawber's Diseases of the Nails and their Management

Baran and Dawber's Diseases of the Nails and their Management
Author: Robert Baran
Publisher: Wiley-Blackwell
Total Pages: 656
Release: 2001-12-04
Genre: Medical
ISBN: 9780632053582

This new edition brings together five leading authorities in nail surgery in this well established and definitive textbook. The entire text is extended in this edition, and particular emphasis is placed on the advances in treatments that have taken place in recent years. Considerable strides have been made in the treatment of fungal diseases (onychomycoses) with the appearance of new therapeutic agents. There is also much greater coverage of nail surgery to reflect the increasing involvement of the dermatologist in this field. The section on nail tumours has also been expanded. Drs Baran and Dawber have been joined by David de Berker, Eckhart Haneke and Antonella Tosti on the editorial team. This move is representative of the major European contribution to the field of nail surgery in recent years. Significant contribution has come from Dr Elvin Zook, the eminent American hand surgeon, who has helped to ensure that the book is as relevant in North America as it is in Europe.

The Nail in Health and Disease

The Nail in Health and Disease
Author: N. Zaias
Publisher: Springer Science & Business Media
Total Pages: 255
Release: 2012-12-06
Genre: Medical
ISBN: 9401178461

The primary intent of this book is to familiarize the medical practitioner with the "nail unit" in a way which will render, correctly and more easily, the diagnosis of nail diseases. At the same time, it serves to encourage the treatment and corrective measures of the ab normalities, if possible, based on anatomical and physiological knowledge. The chapters on anatomy, regeneration, and nail formation are basic to the author's in tent. The content ofthe references quoted represents information which is proven and not controversial material. In addition, my own material not previously published is included. I would like to introduce the anatomical concept that the nail unit consists of four dif ferent epithelial structures, each with its own characteristics, yet all interrelated. These four constituents are the Proximal Nail Fold (PNF), the Matrix (M), the Nail Bed (NB) and the Hyponychium (HYP). A disease may occur in any number of or all nail unit structures. A clear understanding of the anatomy, histology, and tissue kinetics of each constituent will be necessary and is the key factor in interpreting the abnormal findings of each of these constituents as disease occurs. It follows, therefore, that treatment and Cor rective measures should include the knowledge of not only the nail but also of its relation ship to the bony phalanx and the digit.

Textbook of Cosmetic Dermatology

Textbook of Cosmetic Dermatology
Author: Robert Baran
Publisher: CRC Press
Total Pages: 492
Release: 2024-10-31
Genre: Medical
ISBN: 1040110061

This text documents the science that lies behind the expanding field of cosmetic dermatology so that clinicians can practice with confidence and researchers can be fully aware of the clinical implications of their work. New chapters have been added to this edition on skin bioengineering, skin imaging, sunscreens, gel nail polish, management of hair loss, cosmetics and moisturizers in acne management, cryolipolysis, and radiofrequency for minimally invasive body contouring, amongst others, and chapters have been updated throughout to keep this at the forefront of work and practice. The Series in Cosmetic and Laser Therapy is published in association with the Journal of Cosmetic and Laser Therapy.

An Atlas of Diseases of the Nail

An Atlas of Diseases of the Nail
Author: Phoebe Rich
Publisher: CRC Press
Total Pages: 186
Release: 2003-05-28
Genre: Medical
ISBN: 1135384800

Diseases of the nail represent a surprisingly large section of most dermatologists' practice - and can present difficult, sometimes intractable, clinical problems. Co-authored by one of the world's foremost authorities in the field, An Atlas of Diseases of the Nail provides expert and authoritative guidance on all aspects of diagnosis and managemen