The Unexpected Consequences Of Iron Overload
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| Author | : James Minter |
| Publisher | : James Minter |
| Total Pages | : 265 |
| Release | : 2012-10-12 |
| Genre | : Fiction |
| ISBN | : 1479392421 |
Jimmy Kavanagh has a genetic condition where he absorbs and stores iron from his diet over and above the body's requirements (Haemochromatosis). He is unaware of this. As time progresses, with increased ferritin levels he exhibits many traits of storing iron: oxidisation (rusting), becoming magnetised, and having strong bones (excess iron is stored in bone marrow). Through various childhood experiences he realises he is different but doesn't know why. After a significant event in which he saves Barbara, the woman of his dreams, from possible death he realises he can control his magnetism. His life is further complicated after coming to the attention of the KGB. They are interested in all things paranormal, and the CIA who are determined to stop the Russians. Life for Jimmy is further complicated by Sheila. Her father is Irish though she was born in Australia. Unbeknownst to her she has Haemochromatosis but of course, from the Southern hemisphere her polarity is reversed. Will Jimmy and Barbara live happily ever after? Can he manage to thwart the Russians, and CIA. Since opposites attract does his future lay with Sheila?
| Author | : Christopher Michael DeGiorgio |
| Publisher | : Frontiers Media SA |
| Total Pages | : 86 |
| Release | : 2022-02-21 |
| Genre | : Medical |
| ISBN | : 2889744612 |
We would like to acknowledge that Dr. Luke Allen , University College London, has acted as a coordinator and has contributed to the preparation of the proposal for this Research Topic.
| Author | : James C. Barton |
| Publisher | : Cambridge University Press |
| Total Pages | : |
| Release | : 2010-07-22 |
| Genre | : Medical |
| ISBN | : 1139489399 |
A practical, clinically-oriented handbook of iron overload disorders giving a compact guide to normal iron metabolism, iron-related pathobiology, and the diagnosis and management of heritable and acquired iron overload disorders. Many of these disorders were discovered and characterized only in the last decade, and are unmentioned or inadequately described in most texts. Written by clinicians for clinicians, this handbook summarizes information on diverse iron overload conditions, including their history, signs, symptoms, physical examination findings, genetics, genotype-phenotype correlations, pathophysiology, differential diagnosis and treatment. Most physicians, regardless of specialty, encounter patients with systemic or organ-specific iron overload conditions. This book contains essential information for practising adult and pediatric medical specialists in the fields of hematology, gastroenterology, hepatology, rheumatology, endocrinology, diabetology, neurology, oncology, dermatology and internal medicine. Pathologists, pharmacologists, geneticists, genetic counselors and epidemiologists will also find substantial, up-to-date sections in this handbook that are pertinent to their respective fields of interest.
| Author | : James C. Barton |
| Publisher | : Cambridge University Press |
| Total Pages | : 622 |
| Release | : 2000-01-13 |
| Genre | : Medical |
| ISBN | : 9780521593809 |
Once thought rare, hemochromatosis is now acknowledged as one of the commonest inherited disorders, affecting one in two hundred people of western Caucasian descent. It is estimated to affect over one million people in the USA alone. This is the most comprehensive clinical reference yet on hemochromatosis. The international author team includes specialists in internal medicine, hematology, hepatology, genetics, biochemistry and molecular biology, and the contents cover all aspects of pathophysiology, epidemiology, diagnosis and treatment. The latest developments in the genetics of the disorder are well explained, and there are sections on screening, diagnostic techniques, and clinical complications. Social and ethical issues are also considered. Highly illustrated, up-to-date and authoritative, this is the definitive resource for all clinicians involved in the management of hemochromatosis, and will also be invaluable to scientists interested in iron metabolism and iron overload.
| Author | : Gregory J. Anderson |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 705 |
| Release | : 2012-01-16 |
| Genre | : Medical |
| ISBN | : 1603274847 |
Iron Physiology and Pathophysiology in Humans provides health professionals in many areas of research and practice with the most up-to-date and well-referenced volume on the importance of iron as a nutrient and its role in health and disease. This important new volume is the benchmark in the complex area of interrelationships between the essentiality of iron, its functions throughout the body, including its critical role in erythropoiesis, the biochemistry and clinical relevance of iron-containing enzymes and other molecules involved in iron absorption, transport and metabolism, he importance of optimal iron status on immune function, and links between iron and the liver, heart, brain and other organs. Moreover, the interactions between genetic and environmental factors and the numerous co-morbidities seen with both iron deficiency and iron overload in at risk populations are clearly delineated so that students as well as practitioners can better understand the complexities of these interactions. Key features of the volume include an in-depth index and recommendations and practice guidelines are included in relevant chapters. The volume contains more than 100 detailed tables and informative figures and up-to-date references that provide the reader with excellent sources of information about the critical role of iron nutrition, optimal iron status and the adverse clinical consequences of altered iron homeostasis. Iron Physiology and Pathophysiology in Humans is an excellent new text as well as the most authoritative resource in the field.
| Author | : Gary S. Firestein |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 3010 |
| Release | : 2024-07-24 |
| Genre | : Medical |
| ISBN | : 0323935907 |
With its comprehensive, global coverage of all aspects of diagnosis, screening, and treatment in both adults and children, Firestein & Kelley's Textbook of Rheumatology remains your reference of choice in this evolving field. The fully revised 12th Edition retains the user-friendly, full color format, providing in-depth guidance in rheumatology with an ideal balance of basic science and clinical application. New editors, new chapters, and new illustrations keep you fully up to date on recent advances in genetics and the microbiome, current therapies, and other rapid changes in the field. - Covers everything from basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, physical examination, and disease pathogenesis, manifestations and treatment―including key data on outcomes to better inform clinical decision making. - Includes new or significantly revised chapters on Pre-Clinical Autoimmunity; The Microbiome in Health and Disease; Physical Therapy and Rehabilitation; Nutrition and Rheumatic Disease; Classification and Epidemiology of Spondyloarthritis; Etiology and Pathogenesis of Osteoarthritis; COVID and Rheumatic Disease; Vaccination in Rheumatic Disease; Autoimmune Complications of Immune Checkpoint Inhibitors for Cancer; and many more. - Features 1,200 high-quality illustrations, including superb line art, quick-reference tables, and full-color clinical photographs; many new illustrations highlight diseases among racially diverse patients. - Shares the knowledge and expertise of internationally renowned scientists and clinicians, including new editors Drs. Ted Mikuls and Tuhina Neogi. - Demonstrates the complete musculoskeletal exam in online videos, including abnormal findings and the arthroscopic presentation of diseased joints.
| Author | : Susu M Zughaier |
| Publisher | : Frontiers Media SA |
| Total Pages | : 156 |
| Release | : 2018-12-27 |
| Genre | : |
| ISBN | : 2889456625 |
The collection of articles published in this eBook represent different facets of the interactions between pathogens and their host concerning the battle for iron. Pathogens have developed different strategies to acquire iron from their host. These include the production of siderophores, heme acquisition and ferrous iron uptake.
| Author | : Romil Saxena |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 726 |
| Release | : 2011-02-11 |
| Genre | : Medical |
| ISBN | : 1455711969 |
Practical Hepatic Pathology—a new volume in the new Pattern Recognition series—offers you a practical guide to diagnosing every challenging liver biopsy that you encounter in your daily practice. Dr. Romil Saxena presents diagnoses according to a pattern-based organization that guides you from a histological pattern of injury, through the appropriate work-up, around the pitfalls, and to the best diagnosis. Lavish, full-color images capture key hepatic pathology patterns of injury, pathognomonic features and common variations of all major liver diseases and hepatic neoplasms. No other single source delivers the practical, hands-on information you need to solve even the toughest diagnostic challenges in liver biopsies. Recognize the basic patterns of liver injury through an algorithmic approach and establish diagnosis by a pattern-based visual index present at the beginning of the book. Evaluate and interpret biopsy samples using superb, high-quality, full-color images that illustrate pathognomonic features and common variations. Get comprehensive information on major adult and childhood liver diseases, hepatic neoplasms and pre-neoplastic nodules including clinical features, laboratory tests, imaging findings and differential diagnosis. Understand the pathology and practice of liver transplantation with coverage of the clinical aspects of this procedure.
| Author | : Lionel Bercovitch |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 245 |
| Release | : 2011-12-07 |
| Genre | : Medical |
| ISBN | : 1447121902 |
There has been a sea-change in dermatology in the last three decades. Managed care, electronic records and communication, cosmetic dermatology, direct-to-consumer advertising, core competencies, and conflicts of interest were either nascent concepts or not even on the horizon as recently as the mid-1980s. The public, accrediting organizations, and physicians themselves recognize the need for training resources in dermatology ethics and professionalism. There is a need to address these topics in a format that will stimulate dialogue and reflection.
| Author | : Sangkot Marzuki |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 390 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1461500591 |
Tropical Diseases: From Molecule to Bedside covers a wide range of topics that reflect perspectives of northern and southern hemispheres. Fittingly, it defines tropical diseases in a broader-than-usual manner. The book discusses traditional tropical medicine topics of infectious diseases and nutritional deficiencies. These diseases are common in the tropics, although some are associated more with poverty than with tropical living conditions. It also deals with genetic diseases and genomic issues that are truly associated with living in the tropics, e.g. the thalassemias. The book begins with several papers describing the vast human genetic diversity of Southeast Asia and its relationship to several genetic disorders. These papers illustrate the future direction of genomic activities in relation to disease susceptibility and resistance. The next sections deal with malaria and four specific viral and bacterial diseases of the tropics: hepatitis B and C, tuberculosis, and leprosy, followed by a section on general bacterial infection. Two papers on nutrition complete the volume.
