From Lake Coeur d’Alene to its confluence with the Columbia, the Spokane River travels 111 miles of varied and often spectacular terrain—rural, urban, in places wild. The river has been a trading and gathering place for Indigenous peoples for thousands of years. With bountiful trout, accessible swimming holes, and challenging rapids, it is a recreational magnet for residents and tourists alike. The Spokane also bears the legacy of industrial growth and remains caught amid interests competing over natural resources. The contributors to this collection profile this living river through personal reflection, history, science, and poetry. They bring a keen environmental awareness of resource scarcity, climate change, and cultural survival tied to the river’s fate.