Distance measure and similarity measure have been applied to various multi-criteria decision-making environments, like talent selections, fault diagnoses and so on. Some improved distance and similarity measures have been proposed by some researchers. However, hesitancy is reflected in all aspects of life, thus the hesitant information needs to be considered in measures. Then, it can effectively avoid the loss of fuzzy information. However, regarding fuzzy information, it only reflects the subjective factor. Obviously, this is a shortcoming thatwill result in an inaccurate decision conclusion. Thus, based on the definition of a probabilistic neutrosophic hesitant fuzzy set (PNHFS), as an extended theory of fuzzy set, the basic definition of distance, similarity and entropy measures of PNHFS are established. Next, the interconnection among the distance, similarity and entropy measures are studied. Simultaneously, a novel measure model is established based on the PNHFSs. In addition, the new measure model is compared by some existed measures. Finally, we display their applicability concerning the investment problems, which can be utilized to avoid redundant evaluation processes.