The RNA Revolution in Embryonic Development and Cell Differentiation in Health and Disease
| Author | : Francesco Fazi |
| Publisher | : Frontiers Media SA |
| Total Pages | : 229 |
| Release | : 2021-11-02 |
| Genre | : Science |
| ISBN | : 288971571X |
The Rna Revolution In Embryonic Development And Cell Differentiation In Health And Disease
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Heritable Human Genome Editing
| Author | : The Royal Society |
| Publisher | : National Academies Press |
| Total Pages | : 239 |
| Release | : 2021-01-16 |
| Genre | : Medical |
| ISBN | : 0309671132 |
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
Robbins & Cotran Pathologic Basis of Disease E-Book
| Author | : Vinay Kumar |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 1396 |
| Release | : 2020-05-18 |
| Genre | : Medical |
| ISBN | : 0323609937 |
Readable and highly illustrated, Robbins and Cotran Pathologic Basis of Disease, 10th Edition presents an in-depth, state-of-the-art overview of human diseases and their cellular and molecular basis. This best-selling text delivers the latest, most essential pathology knowledge in a readable, interesting manner, ensuring optimal understanding of the latest basic science and clinical content. More than 1,000 high-quality photographs and full-color illustrations highlight new information in molecular biology, disease classifications, new drugs and drug therapies, and much more. This superb learning package also includes an enhanced eBook with a full complement of ancillary content on Student Consult. - Provides uniquely authoritative and readable coverage, ideal for USMLE or specialty board preparation, as well as for coursework. - Covers the hot topics you need to know about, including novel therapies for hepatitis C, classification of lymphomas, unfolded protein response, non-apoptotic pathways of cell death, coronavirus infections, liquid biopsy for cancer detection, regulation of iron absorption, clonal hematopoiesis and atherosclerosis, thrombotic microangiopathies, heparin-induced thrombocytopenias, inflammatory myopathies, genetic tools for treatment of cystic fibrosis, and many more. - Uses an outstanding full-color, user-friendly design to simplify your study and quickly direct you to the information you need to know, with learning features such as boldface overviews at the beginning of each section, key concepts boxes, suggested readings, schematic diagrams that illustrate complex concepts, and new gross and microscopic figures for clarity of morphology. - Brings you up to date with the latest information in molecular and genetic testing, mechanisms of disease, personalized medicine and its impact on treatment of human diseases, the role of microbiome and metabolome in non-communicable diseases, and much more. - Provides access to a wealth of interactive ancillaries online: pathology case studies, videos, self-assessment questions, Targeted Therapy boxes that discuss drug therapy for specific diseases, interactive cases, and more. - Evolve Instructor site with an image and test bank is available to instructors through their Elsevier sales rep or via request at https://evolve.elsevier.com.
Robbins & Cotran Pathologic Basis of Disease, 10e: South Asia Edition, 2 Vol SET E-Book
| Author | : Vinay Kumar |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 1494 |
| Release | : 2020-07-22 |
| Genre | : Medical |
| ISBN | : 813126212X |
Readable and highly illustrated, Robbins and Cotran Pathologic Basis of Disease, South Asia Edition presents an in-depth, state-of-the-art overview of human diseases and their cellular and molecular basis. This best-selling text delivers the latest, most essential pathology knowledge in a readable, interesting manner, ensuring optimal understanding of the latest basic science and clinical content. More than 1,000 high-quality photographs and full-color illustrations highlight new information in molecular biology, disease classifications, new drugs and drug therapies, and much more - Provides uniquely authoritative and readable coverage, ideal for USMLE or specialty board preparation, as well as for coursework. - Covers the hot topics you need to know about, including novel therapies for hepatitis C, classification of lymphomas, unfolded protein response, non-apoptotic pathways of cell death, coronavirus infections, liquid biopsy for cancer detection, regulation of iron absorption, clonal hematopoiesis and atherosclerosis, thrombotic microangiopathies, heparin-induced thrombocytopenias, inflammatory myopathies, genetic tools for treatment of cystic fibrosis, and many more. - Uses an outstanding full-color, user-friendly design to simplify your study and quickly direct you to the information you need to know, with learning features such as boldface overviews at the beginning of each section, key concepts boxes, suggested readings, schematic diagrams that illustrate complex concepts, and new gross and microscopic figures for clarity of morphology. - Brings you up to date with the latest information in molecular and genetic testing, mechanisms of disease, personalized medicine and its impact on treatment of human diseases, the role of microbiome and metabolome in non-communicable diseases, and much more. - New to the edition from South Asia - Neoplasia • Infectious Diseases • Diseases of White Blood Cells, Lymph Nodes, Spleen, and Thymus • Red Blood Cell and Bleeding Disorders • The Lung • Head and Neck • The Gastrointestinal Tract • Liver and Gallbladder • The Kidney • The Breast • The Endocrine System • The Skin • The Central Nervous System • The Eye • Transfusion Medicine
Pulmonary Vasculature Redox Signaling in Health and Disease
| Author | : Yong-Xiao Wang |
| Publisher | : Springer |
| Total Pages | : 429 |
| Release | : 2017-10-18 |
| Genre | : Medical |
| ISBN | : 3319632450 |
The main goal of this book is to form a high-quality platform in which well-known and emerging pioneering basic, translational and clinical scientists can present their latest, exciting findings in the studies of redox signaling in the pulmonary vasculature. Content from outstanding investigators with unique expertise and skills of molecular and cell biology, biochemistry, physiology, pharmacology, biophysics, biotechnology and medicine will update our current out-of-date concepts with new knowledge. Rapidly increasing scientific studies have gathered a large volume of novel and important information on redox signaling in healthy and diseased pulmonary vasculature. This volume covers the need for a cohesive book to display state-of-the-art advances in the field. The second major aim of this book is to help direct future research. Redox signaling is a major molecular process involved in almost every physiologic cellular response in the pulmonary vasculature including energy metabolism, host defense, gene expression, contraction, proliferation, and migration. Aberrancy in this important signaling pathway leads to a critical role in the development of nearly all pulmonary diseases, such as pulmonary hypertension, cor pulmonale, pulmonary edema, and vasculitis, among others.
The Art and Politics of Science
| Author | : Harold Varmus |
| Publisher | : W. W. Norton & Company |
| Total Pages | : 330 |
| Release | : 2010-05-24 |
| Genre | : Biography & Autobiography |
| ISBN | : 0393073564 |
A Nobel Prize–winning cancer biologist, leader of major scientific institutions, and scientific adviser to President Obama reflects on his remarkable career. A PhD candidate in English literature at Harvard University, Harold Varmus discovered he was drawn instead to medicine and eventually found himself at the forefront of cancer research at the University of California, San Francisco. In this “timely memoir of a remarkable career” (American Scientist), Varmus considers a life’s work that thus far includes not only the groundbreaking research that won him a Nobel Prize but also six years as the director of the National Institutes of Health; his current position as the president of the Memorial Sloan-Kettering Cancer Center; and his important, continuing work as scientific adviser to President Obama. From this truly unique perspective, Varmus shares his experiences from the trenches of politicized battlegrounds ranging from budget fights to stem cell research, global health to science publishing.
Hematopoietic Differentiation of Human Pluripotent Stem Cells
| Author | : Tao Cheng |
| Publisher | : Springer |
| Total Pages | : 131 |
| Release | : 2015-08-25 |
| Genre | : Medical |
| ISBN | : 9401773122 |
This book features the most cutting-edge work from the world’s leading laboratories in this field and provides practical methods for differentiating pluripotent stem cells into hematopoietic lineages in the blood system. Pluripotent stem cells have attracted major interest from a fast-growing and multidisciplinary community of researchers who are developing new techniques for the derivation and differentiation of these cells into specific cell lineages. These direct differentiation methods hold great promise for the translational applications of these cells. This book is an essential reference work for researchers at all levels in the fields of hematology and stem cell biology, as well as clinical practitioners in regenerative medicine.
The Epigenetics Revolution
| Author | : Nessa Carey |
| Publisher | : Columbia University Press |
| Total Pages | : 353 |
| Release | : 2012-03-06 |
| Genre | : Science |
| ISBN | : 0231530714 |
Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.
Robbins Basic Pathology E-Book
| Author | : Vinay Kumar |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 955 |
| Release | : 2017-03-08 |
| Genre | : Medical |
| ISBN | : 0323394132 |
Part of the trusted Robbins and Cotran family, Robbins Basic Pathology provides a readable, well-illustrated and concise overview of the principles of human pathology that's ideal for today's busy students. This thoroughly revised edition continues with a strong emphasis on pathogenesis and the clinical features of disease, adding new artwork and more schematic diagrams to further aid in summarizing key pathologic processes and expand the already impressive illustration program. - Excellent art program boasts high-quality photomicrographs, gross photos, and radiologic images to supplement the world-class illustrations. - Bulleted summary boxes provide quick access to key information and easy review of key concepts. - Highlights pathogenesis, morphology, and pathophysiologic content throughout. - Includes increased and updated clinical topics. - New artwork and more schematic diagrams summarize key pathologic processes. - An all-star editorial team enables you to gain a rich understanding of all essential pathology concepts. - Student Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and images from the book on a variety of devices. You'll also access virtual microscope slides, self-assessment questions, additional images, updated pathology case studies, and Targeted Therapy boxes.
Robbins and Kumar Basic Pathology: First South Asia Edition - E-Book
| Author | : Vinay Kumar |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 950 |
| Release | : 2017-06-23 |
| Genre | : Medical |
| ISBN | : 813124959X |
Part of the trusted Robbins and Cotran family, Robbins Basic Pathology provides a readable, well-illustrated and concise overview of the principles of human pathology that's ideal for today's busy students. This thoroughly revised edition continues with a strong emphasis on pathogenesis and the clinical features of disease, adding new artwork and more schematic diagrams to further aid in summarizing key pathologic processes and expand the already impressive illustration program. - Excellent art program boasts high-quality photomicrographs, gross photos, and radiologic images to supplement the world-class illustrations. - Bulleted summary boxes provide quick access to key information and easy review of key concepts. - Highlights pathogenesis, morphology, and pathophysiologic content throughout.
