The Right Therapy for Neurological Disorders

The Right Therapy for Neurological Disorders
Author: E. Beghi
Publisher: Karger Medical and Scientific Publishers
Total Pages: 180
Release: 2016-07-26
Genre: Medical
ISBN: 3318058653

Most neurological disorders are chronic and aging-related. With the increase of life expectancy their incidence and prevalence will grow in the decades to come, which in turn will increase the load on medical and social systems worldwide. There is thus a desperate need for successful preventive and therapeutic measures based on randomized clinical trials (RTCs) conducted by independent organizations. This book provides a compendium relating most of the principles of reliable RTCs to specific neurological diseases. Contributed by specialized neurologists, the articles touch on important aspects of RCTs with a clear critical approach, highlighting their limitations as well as giving recommendations for their planning and conducting to address the variable genotypic and phenotypic aspects of neurological conditions. Consideration is also given to combining the clinical impact of the study results with patients’ values and the interests of pharmaceutical companies. Neurologists involved in clinical trials will certainly benefit from this book, which should become a basic text for all neurological courses dealing with evidence-based neurology.

Gene Therapy in Neurological Disorders

Gene Therapy in Neurological Disorders
Author: Mingjie Li
Publisher: Academic Press
Total Pages: 450
Release: 2018-05-25
Genre: Medical
ISBN: 012809821X

Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific neurological disorders. Each chapter gives an in-depth introduction to the relevant field before diving into the specific tool or application. The book aims to help investigators, students and research staff better understand the principles of gene therapy and its application in the nervous system. - Provides background information and experimental details of gene therapy tools applied for neuroscience research and neurological disorders - Covers a broad range of gene delivery and regulation tools, therapeutic agents, and target cells, including emerging new technologies such as CRISPR/Cas9 genome editing - Discusses applications of gene therapy tools to neurological disorders including neurodegeneration, muscular dystrophy, trauma and chronic pain, and neoplastic diseases

Behavioral Neurology & Neuropsychiatry

Behavioral Neurology & Neuropsychiatry
Author: David B. Arciniegas
Publisher: Cambridge University Press
Total Pages: 685
Release: 2013-01-24
Genre: Medical
ISBN: 0521875013

The merger of behavioral neurology and neuropsychiatry into a single medical subspecialty, Behavioral Neurology & Neuropsychiatry, requires an understanding of brain-behavior relationships and a clinical approach that transcends the traditional perspectives of neurology and psychiatry. Designed as a primer of concepts and principles, and authored by a multidisciplinary group of internationally known clinical neuroscientists, this book divides into three sections: • Structural and Functional Neuroanatomy (Section I) addresses the neuroanatomy and phenomenology of cognition, emotion, and behavior • Clinical Assessment (Section II) describes neuropsychiatric history taking, neurological and mental status examinations, neuropsychological assessment, and neuroimaging, electrophysiologic, and laboratory methods • Treatment (Section III) discusses environmental, behavioral, rehabilitative, psychological, social, pharmacological, and procedural interventions for cognitive, emotional, and behavioral disorders. By emphasizing the principles of Behavioral Neurology & Neuropsychiatry, this book will improve your understanding of brain-behavior relationships and inform your care of patients and families affected by neurobehavioral disorders.

Neurological Disorders

Neurological Disorders
Author: Thomas Brandt
Publisher: Gulf Professional Publishing
Total Pages: 1606
Release: 2003-01-03
Genre: Medical
ISBN: 9780121258313

This single-volume reference covers the natural course, treatment, and management of all neurological diseases affecting the brain, spinal cord nerves and muscles. This comprehensive text reference seeks to assist physicians with treatment by providing an easy-to-use compendium covering the treatment and management of all neurological diseases along with details on the natural course of these diseases. Organized for ease of use and quick reference, each chapter presents a neurological disorder or key symptoms and systematically discusses the clinical syndrome and differential diagnosis, natural course, principles of therapy, and practical management of each. Covers wide range of neurological conditions and potential treatments, including the evidence for and against each treatment Describes the spontaneous course of neurological diseases along with discussion of the management of different stages and variants of a disorder Presents special situations and exceptional cases in which alternative therapies should be considered

Occupational Therapy and Neurological Conditions

Occupational Therapy and Neurological Conditions
Author: Jenny Preston
Publisher: John Wiley & Sons
Total Pages: 232
Release: 2016-03-22
Genre: Medical
ISBN: 1118936132

While diagnosis with a neurological condition may not be life-threatening, it can have significant impact on everyday life and on participation in activities. Occupational therapists must be able to fully consider the physical, cognitive, emotional, psychological and behavioural problems which may occur as a consequence of a neurological disorder, and understand the impact of diagnosis from a person-centred perspective. Occupational Therapy and Neurological Conditions incorporates theoretical, clinical and research evidence to support occupational therapists in the management of people with neurological conditions. Covers the key symptoms of neurological conditions and the biological basis of these within the ICF framework Provides an overview of therapy and management for all neurological conditions Includes key occupational therapy theory Case studies root concepts in real-life practice End-of-chapter self-evaluation questions help test understanding Occupational Therapy and Neurological Conditions is the ideal resource to support students, newly-qualified practitioners, and occupational therapists looking for an overview or introduction to this key area of practice.

Functional Neurologic Disorders

Functional Neurologic Disorders
Author:
Publisher: Academic Press
Total Pages: 684
Release: 2016-10-06
Genre: Medical
ISBN: 0128018496

Functional Neurologic Disorders, the latest volume in the Handbook of Clinical Neurology series, summarizes state-of-the-art research findings and clinical practice on this class of disorders at the interface between neurology and psychiatry. This 51-chapter volume offers an historical introduction, chapters on epidemiology and pathophysiolology, a large section on the clinical features of different type of functional neurologic symptoms and disorders (including functional movement disorders, non-epileptic seizures, dizziness, vision, hearing, speech and cognitive symptoms), and then concluding with approaches to therapy. This group of internationally acclaimed experts in neurology, psychiatry, and neuroscience represent a broad spectrum of areas of expertise, chosen for their ability to write clearly and concisely with an eye toward a clinical audience. This HCN volume sets a new landmark standard for a comprehensive, multi-authored work dealing with functional neurologic disorders (also described as psychogenic, dissociative or conversion disorders). - Offers a comprehensive interdisciplinary approach for the care of patients with functional disorders seen in neurologic practice, leading to more efficient prevention, management, and treatment - Provides a synthesis of research efforts incorporating clinical, brain imaging and neurophysiological studies - Fills an existing gap between traditional neurology and traditional psychiatry - Contents include coverage of history, epidemiology, clinical presentations, and therapy - Edited work with chapters authored by leaders in the field, the broadest, most expert coverage available

Art Therapy with Neurological Conditions

Art Therapy with Neurological Conditions
Author: Marian Liebmann
Publisher: Jessica Kingsley Publishers
Total Pages: 370
Release: 2015-05-21
Genre: Psychology
ISBN: 0857009125

By creating a therapeutic outlet for self-expression and processing trauma, art therapy can play a powerful role in assisting people with a brain injury or neurological condition to adjust to living with altered abilities and ways of thinking. Bringing together a wealth of expertise from specialists working with a range of conditions including epilepsy, dementia, acquired brain injury, motor neurone disease and multiple sclerosis, this book describes both the effects of the conditions and the ways in which art therapy has helped in the rehabilitation process. The book includes work with groups and individuals and with a wide range of settings and age groups, from children to older adults, and discusses the implications of research from neuroscience and neuropsychology. This will be essential reading for art therapists and students working with neurological conditions. Other professionals working with people with neurological conditions such as psychotherapists and counsellors, doctors, nurses and complementary therapists will also find it of interest.

Disease Control Priorities, Third Edition (Volume 4)

Disease Control Priorities, Third Edition (Volume 4)
Author: Vikram Patel
Publisher: World Bank Publications
Total Pages: 307
Release: 2016-03-10
Genre: Medical
ISBN: 1464804281

Mental, neurological, and substance use disorders are common, highly disabling, and associated with significant premature mortality. The impact of these disorders on the social and economic well-being of individuals, families, and societies is large, growing, and underestimated. Despite this burden, these disorders have been systematically neglected, particularly in low- and middle-income countries, with pitifully small contributions to scaling up cost-effective prevention and treatment strategies. Systematically compiling the substantial existing knowledge to address this inequity is the central goal of this volume. This evidence-base can help policy makers in resource-constrained settings as they prioritize programs and interventions to address these disorders.

Gene Therapy for Neurological Disorders and Brain Tumors

Gene Therapy for Neurological Disorders and Brain Tumors
Author: E. Antonio Chiocca
Publisher: Springer Science & Business Media
Total Pages: 458
Release: 1997-10-23
Genre: Medical
ISBN: 1592594786

Leading gene therapy researchers and clinicians illuminate the field-from basic vector technology to current and future clinical applications in neurology. The authoritative contributors provide cutting-edge reviews of the vectors available for gene transfer to the central nervous system, the strategies against CNS tumors, the potential strategies against neurologic disorder, and the limitations of today's gene therapy approaches. Also discussed are significant applications of gene therapy to brain tumors, Parkinson's disease, ischemia, and Huntington's chorea. Readers will learn the current delivery methods for transgenes, will learn the characteristics of transgene delivery vectors, and come to understand the therapy for both neuro-oncologic and neurologic disorders.

Clinical Neuroepidemiology of Acute and Chronic Disorders

Clinical Neuroepidemiology of Acute and Chronic Disorders
Author: Jahangir Moini
Publisher: Elsevier
Total Pages: 454
Release: 2023-05-12
Genre: Medical
ISBN: 0323959024

Clinical Neuroepidemiology of Acute and Chronic Disorders explores the epidemiology of disorders that affect the nervous system, providing comprehensive discussions on incidence, prevalence, and more. With thorough coverage of a variety of disorders, chapters detail etiology, risk factors, pathophysiology, clinical manifestations, diagnosis, global incidence and prevalence, age-specific incidence, global mortality, prevention, treatment and prognosis for each disorder. Chapters uniquely discuss the effects of the COVID-19 coronavirus upon the nervous system and in relation to several diseases, including new discoveries and treatments for Alzheimer's disease and migraine headaches. Real-world case studies with critical thinking questions and "Focus On" boxes highlight important information. - Covers a variety of disorders and their etiology, including risk factors, pathophysiology clinical manifestations diagnosis, incidence of mortality, prevention, treatment and prognosis - Features real-world case studies with critical thinking questions and answers - Includes Focus On boxes that highlight key information in each chapter - Highlights treatments for various disorders, including Alzheimer's disease and migraines - Discusses the effects of COVID-19 on the nervous system in relation to several diseases