This research focusses attention on the social-demographic, agricultural and tourist aspects of the 29 municipalities of the Molise Region, in order to provide new elements and details in a distributive and diachronic analysis and underline the link between new data and old problems which require collective actions to reach common purposes and to enhance the local resources according to the different vocations. After the examination of numerous statistical data which are also represented through GIS elaborations, quality of products and processes, multi-functional and inter-sectorial relationships, fast and slow scenarios, new or renewed forms of tourism accommodation, internet and tourist social technologies, social agriculture and neo-agrarianism, slow and creative tourism, the high environmental quality, enriched by historical and cultural heritage, become some of the keywords around which the geographical analysis is conducted. The present study seeks both to provide useful input for a meticulous and weighted planning, according to a resource-based approach, and to define a reference framework for people who are no longer live in Molise Region and Italy, but who are still emotionally attached to their native lands and keep alive the memories for their origins or for the origins of their parents.