The Evolution in Pharmacology of Infectious Diseases: 2022

The Evolution in Pharmacology of Infectious Diseases: 2022
Author: Exequiel Oscar Jesus Porta
Publisher: Frontiers Media SA
Total Pages: 157
Release: 2024-03-21
Genre: Science
ISBN: 2832546617

There have been tremendous advancements in the Pharmacology of Infectious Diseases in recent years. These recent advancements underline the importance of a multidisciplinary approach in the study of infectious diseases. In order to explore this fast-growing area, Frontiers is launching a new series of Research Topics focusing on the evolution of methods, processes, scientific breakthroughs and technology advances in the field of Pharmacology of Infectious Diseases. In this article collection, we seek contributions exploring the changing context, the recent advances, the challenges, and the emerging new perspectives within the field.

Emerging Viruses

Emerging Viruses
Author: Stephen S. Morse
Publisher: Oxford University Press
Total Pages: 342
Release: 1996-08-01
Genre: Medical
ISBN: 0195355741

New epidemics such as AIDS and "mad cow" disease have dramatized the need to explore the factors underlying rapid viral evolution and emerging viruses. This comprehensive volume is the first to describe this multifaceted new field. It places viral evolution and emergence in a historical context, describes the interaction of viruses with hosts, and details the advances in molecular biology and epidemiology that have provided the tools necessary to track developing viral epidemics and to detect new viruses far more successfully than could be done in the recent past. This unique book also lucidly details case histories and offers practical suggestions for the prevention of future epidemics. The contributors are leading authorities in their disciplines, and were selected both for their expert knowledge and for their ability to define and elucidate the fundamental issues. The book is highly accessible and has been written for a wide audience that includes virologists, public health authorities, medical anthropologists, evolutionary biologists, geneticists, infectious disease specialists, and social scientists interested in medical and health issues.

Disease Control Priorities, Third Edition (Volume 6)

Disease Control Priorities, Third Edition (Volume 6)
Author: King K. Holmes
Publisher: World Bank Publications
Total Pages: 1027
Release: 2017-11-06
Genre: Medical
ISBN: 1464805253

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Highly Infectious Diseases in Critical Care

Highly Infectious Diseases in Critical Care
Author: Jorge Hidalgo
Publisher: Springer Nature
Total Pages: 285
Release: 2020-01-02
Genre: Medical
ISBN: 3030338037

This book provides a comprehensive overview of highly infectious diseases (HIDs) in the ICU. The text is designed to help critical care specialists and other healthcare practitioners prepare and plan for potential outbreaks of emerging or resurgent HIDs, lead a team in the ICU, perform emergency triage, and provide care for patients with a HID. The book also reviews some of the most prevalent highly infectious diseases, including influenza, SARS, plague, anthrax, and malaria. Written by experts in the field, Highly Infectious Diseases in Critical Care: A Comprehensive Clinical Guide is a valuable resource for critical care and infectious disease specialists who treat patients afflicted with a highly infectious disease in the ICU.

The Stockholm Paradigm

The Stockholm Paradigm
Author: Daniel R. Brooks
Publisher: University of Chicago Press
Total Pages: 423
Release: 2019-07-19
Genre: Science
ISBN: 022663258X

The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change–related threats confronting humanity. Even without deadly global catastrophes on the scale of the 1918 Spanish Influenza pandemic, emerging diseases cost humanity more than a trillion dollars per year in treatment and lost productivity. But while time is short, the danger is great, and we are largely unprepared, the Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can “anticipate to mitigate” emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.

Infectious Diseases of Humans

Infectious Diseases of Humans
Author: Roy M. Anderson
Publisher: Oxford University Press
Total Pages: 772
Release: 1991
Genre: Medical
ISBN: 9780198540403

This book deals with infectious diseases -- viral, bacterial, protozoan and helminth -- in terms of the dynamics of their interaction with host populations. The book combines mathematical models with extensive use of epidemiological and other data. This analytic framework is highly useful for the evaluation of public health strategies aimed at controlling or eradicating particular infections. Such a framework is increasingly important in light of the widespread concern for primary health care programs aimed at such diseases as measles, malaria, river blindness, sleeping sickness, and schistosomiasis, and the advent of AIDS/HIV and other emerging viruses. Throughout the book, the mathematics is used as a tool for thinking clearly about fundamental and applied problems having to do with infectious diseases. The book is divided into two parts, one dealing with microparasites (viruses, bacteria and protozoans) and the other with macroparasites (helminths and parasitic arthropods). Each part begins with simple models, developed in a biologically intuitive way, and then goes on to develop more complicated and realistic models as tools for public health planning. The book synthesizes previous work in this rapidly growing field (much of which is scattered between the ecological and the medical literature) with a good deal of new material.

Sustaining Global Surveillance and Response to Emerging Zoonotic Diseases

Sustaining Global Surveillance and Response to Emerging Zoonotic Diseases
Author: National Research Council
Publisher: National Academies Press
Total Pages: 339
Release: 2010-01-24
Genre: Medical
ISBN: 0309137349

H1N1 ("swine flu"), SARS, mad cow disease, and HIV/AIDS are a few examples of zoonotic diseases-diseases transmitted between humans and animals. Zoonotic diseases are a growing concern given multiple factors: their often novel and unpredictable nature, their ability to emerge anywhere and spread rapidly around the globe, and their major economic toll on several disparate industries. Infectious disease surveillance systems are used to detect this threat to human and animal health. By systematically collecting data on the occurrence of infectious diseases in humans and animals, investigators can track the spread of disease and provide an early warning to human and animal health officials, nationally and internationally, for follow-up and response. Unfortunately, and for many reasons, current disease surveillance has been ineffective or untimely in alerting officials to emerging zoonotic diseases. Sustaining Global Surveillance and Response to Emerging Zoonotic Diseases assesses some of the disease surveillance systems around the world, and recommends ways to improve early detection and response. The book presents solutions for improved coordination between human and animal health sectors, and among governments and international organizations. Parties seeking to improve the detection and response to zoonotic diseases-including U.S. government and international health policy makers, researchers, epidemiologists, human health clinicians, and veterinarians-can use this book to help curtail the threat zoonotic diseases pose to economies, societies, and health.

Evolutionary Medicine

Evolutionary Medicine
Author: Stephen C. Stearns
Publisher: Oxford University Press
Total Pages: 401
Release: 2024-06-18
Genre: Science
ISBN: 0192871994

Evolutionary thinking provides insights into many different areas in the research and practice of medicine and public health. It takes specialties such as medical microbiology, epidemiology, oncology, gynecology, and psychiatry that had become increasingly siloed and places them in a larger framework. This foundational structure enables students to view medical knowledge as an integrated whole, underpinned by general principles rather than a loose collection of disparate facts. The discipline of evolutionary medicine continues to advance rapidly as new results come in showing where the insights pay off and where they do not. Its conceptual foundations have also been strengthened in papers not yet reflected in the textbooks, so a new edition is therefore timely. At the same time, the teaching of evolutionary medicine has also been steadily gaining momentum both in courses that prepare undergraduates for medical school in North America and in other contexts worldwide. Evolutionary Medicine is intended for undergraduate students preparing for careers in medicine and public health, students in schools of medicine and public health, and medical professionals curious about the insights that evolutionary thinking can bring to their field. It will also be relevant to students and researchers in the fields of evolutionary biology, anthropology, developmental biology, and genetics. It highlights the most important insights in a relatively brief and compelling book that does not attempt encyclopedic coverage of a rapidly changing field.

Neonatology Questions and Controversies: Infectious Disease, Immunology, and Pharmacology - E-Book

Neonatology Questions and Controversies: Infectious Disease, Immunology, and Pharmacology - E-Book
Author: William Benitz
Publisher: Elsevier Health Sciences
Total Pages: 291
Release: 2023-08-01
Genre: Medical
ISBN: 0323879373

Dr. Richard Polin's Neonatology Questions and Controversies series highlights the toughest challenges facing physicians and care providers in clinical practice, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today's practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient.The thoroughly updated, full-color, 2nd Edition of Infectious Disease, Immunology, and Pharmacology: - Provides a clear management strategy for common and rare neonatal infectious diseases, offering guidance based on the most up-to-date understanding of underlying pathophysiology. - Places emphasis on controversial areas that can entail different approaches. - Features the most current clinical information throughout, including a new immunology section that covers inborn errors of immunity presenting in the newborn period and clinical and molecular markers for diagnosis of neonatal sepsis. - Includes new chapters on COVID-19; congenital syphilis; gonococcal eye prophylaxis; organ dysfunction in sepsis and necrotizing enterocolitis; and drug-associated acute kidney injury. - Utilizes a consistent chapter organization to help you find information quickly and easily, and contains numerous charts, graphs, radiographic images, and photographs throughout. - Offers the most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care. Purchase each volume individually, or get the entire 7-volume Neonatology Questions and Controversies set, which includes online access that allows you to search across all titles! - Gastroenterology and Nutrition - Hematology and Transfusion Medicine - Neonatal Hemodynamics - Infectious Disease, Immunology, and Pharmacology - Renal, Fluid, and Electrolyte Disorders - Neurology - The Newborn Lung