The book describes the “nation-building” strategy by which an increasing number of Native communities have set about reclaiming powers of self-determination, strengthening their cultures, and developing their economies. A piece of this movement has been the establishment of new models for tribally-driven and requested relations between universities and American Indian/Alaskan Native communities and organizations. Building on the Harvard Project on American Indian Economic Development’s experience with more than 120 nation-building projects over two decades, Universities and Indian Country posits that the tenets of nation building can provide a strategy for expanding and diversifying universities’ perspectives of knowledge in a multicultural world, while also producing results that are requested by and useful to Native communities. This groundbreaking volume extends the dialogue begun by the Harvard project, providing another venue for the sharing of knowledge and information. The projects presented address a wide range of topics, including the regulation of genetic research, human resource development, tribal fund-raising, development of tribal museums, and freedom of the press in Indian Country. Universities and Indian Country’s focus on the concerns and questions of Native communities themselves, provides insight not only into how projects came together, but also into what significance they have to the tribal partners. This compilation is a valuable resource for any student, professional, or community member concerned with issues of nation building and self-determination.