The Double Strand
Download The Double Strand full books in PDF, epub, and Kindle. Read online free The Double Strand ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
DNA Repair and Mutagenesis
| Author | : Errol C. Friedberg |
| Publisher | : American Society for Microbiology Press |
| Total Pages | : 2587 |
| Release | : 2005-11-22 |
| Genre | : Science |
| ISBN | : 1555813194 |
An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.
Concepts of Biology
| Author | : Samantha Fowler |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2023-05-12 |
| Genre | : |
| ISBN | : 9781739015503 |
Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.
Free-Radical-Induced DNA Damage and Its Repair
| Author | : Clemens von Sonntag |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 554 |
| Release | : 2005-12-02 |
| Genre | : Science |
| ISBN | : 9783540261209 |
The free-radical chemistry of DNA had been discussed in some detail in 1987 in my book The Chemical Basis of Radiation Biology. Obviously, the more recent developments and the concomitant higher level of understanding of mechanistic details are missing. Moreover, in the living cell, free-radical DNA damage is not only induced by ionizing radiation, but free-radical-induced DNA damage is a much more general phenomenon. It was, therefore, felt that it is now timely to review our present knowledge of free-radical-induced DNA damage induced by all conceivable free-radical-generating sources. Originally, it had been thought to include also a very important aspect, the repair of DNA damage by the cell’s various repair enzymes. Kevin Prise (Cancer Campaign, Gray Laboratory, L- don) was so kind to agree to write this part. However, an adequate description of this strongly expanding area would have exceeded the allocated space by much, and this section had to be omitted. The directors of the Max-Planck-Institut für Strahlenchemie (now MPI für Bioanorganische Chemie), Karl Wieghardt and Wolfgang Lubitz, kindly allowed me to continue to use its facilities after my retirement in 2001. Notably, our - brarian, Mrs. Jutta Theurich, and her right-hand help, Mrs. Rosemarie Schr- er, were most helpful in getting hold of the literature. I thank them very much. Without their constant help, this would have been very difficult indeed.
The Nucleolus
| Author | : Mark O. J. Olson |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 434 |
| Release | : 2011-09-15 |
| Genre | : Science |
| ISBN | : 1461405149 |
Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.
Advances in Genetics
| Author | : Jeffrey C. Hall |
| Publisher | : Elsevier |
| Total Pages | : 199 |
| Release | : 2005-11-07 |
| Genre | : Science |
| ISBN | : 0080522335 |
The field of genetics is rapidly evolving and new medical breakthroughs are occurring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.
DNA Repair and Replication
| Author | : Roger J. A. Grand |
| Publisher | : Garland Science |
| Total Pages | : 672 |
| Release | : 2018-09-03 |
| Genre | : Science |
| ISBN | : 0429876548 |
DNA Repair and Replication brings together contributions from active researchers. The first part of this book covers most aspects of the DNA damage response, emphasizing the relationship to replication stress. The second part concentrates on the relevance of this to human disease, with particular focus on both the causes and treatments which make use of DNA Damage Repair (DDR) pathways. Key Selling Features: Chapters written by leading researchers Includes description of replication processes, causes of damage, and methods of repair
DNA Repair in Cancer Therapy
| Author | : Mark R. Kelley |
| Publisher | : Academic Press |
| Total Pages | : 466 |
| Release | : 2016-06-07 |
| Genre | : Science |
| ISBN | : 0128035994 |
DNA Repair and Cancer Therapy: Molecular Targets and Clinical Applications, Second Edition provides a comprehensive and timely reference that focuses on the translational and clinical use of DNA repair as a target area for the development of diagnostic biomarkers and the enhancement of cancer treatment. Experts on DNA repair proteins from all areas of cancer biology research take readers from bench research to new therapeutic approaches. This book provides a detailed discussion of combination therapies, in other words, how the inhibition of repair pathways can be coupled with chemotherapy, radiation, or DNA damaging drugs. Newer areas in this edition include the role of DNA repair in chemotherapy induced peripheral neuropathy, radiation DNA damage, Fanconi anemia cross-link repair, translesion DNA polymerases, BRCA1-BRCA2 pathway for HR and synthetic lethality, and mechanisms of resistance to clinical PARP inhibitors. - Provides a comprehensive overview of the basic and translational research in DNA repair as a cancer therapeutic target - Includes timely updates from the earlier edition, including Fanconi Anemia cross-link repair, translesion DNA polymerases, chemotherapy induced peripheral neuropathy, and many other new areas within DNA repair and cancer therapy - Saves academic, medical, and pharma researchers time by allowing them to quickly access the very latest details on DNA repair and cancer therapy - Assists researchers and research clinicians in understanding the importance of the breakthroughs that are contributing to advances in disease-specific research
Chromosome Translocation
| Author | : Yu Zhang |
| Publisher | : Springer |
| Total Pages | : 171 |
| Release | : 2018-06-28 |
| Genre | : Medical |
| ISBN | : 9811305935 |
This volume discusses various aspects of mechanisms and methodologies of chromosome translocations, ranging from a historical and clinical overview of chromosome translocations to the rapid development of the next-generation sequencing technologies, which has dramatically increased our understanding of the spectrum of chromosome translocations in human diseases. The book also introduces the mechanistic studies on chromosome deletions and their implications in cancer, and discusses the mechanisms of regulating chromothripsis, a unique complex type of chromosome translocation. It is a valuable resource for students and researchers alike, providing insights into chromosome translocations and, potentially, other genomic aberrations involved in understanding and curing human diseases.
Recombinational Repair of DNA Damage
| Author | : Andrei Kuzminov |
| Publisher | : Landes Bioscience |
| Total Pages | : 234 |
| Release | : 1996 |
| Genre | : Medical |
| ISBN | : |
