The development of deep brain stimulation for neurological and psychiatric disorders: clinical, societal and ethical issues

The development of deep brain stimulation for neurological and psychiatric disorders: clinical, societal and ethical issues
Author: Thomas E. Schlaepfer
Publisher: Frontiers E-books
Total Pages: 71
Release:
Genre:
ISBN: 2889190404

To date more than eighty thousand patients worldwide have received deep brain stimulation (DBS), mainly in order to alleviate symptoms of treatment-resistant disorders such as tremor associated with Parkinson’s disease, essential tremor, chronic pain, epilepsy, obsessive compulsive disorder, major depression and Tourette syndrome. The number of indications for neurological and psychiatric conditions using this technology is rapidly increasing, raising important societal and ethical issues that cannot be dealt with by scientists and clinicians on their own, but need discussions among all possible stakeholders on questions such as: what are the comprehensive risks and benefits of this technology? what is the real impact on patients’ life, in terms of health, quality of life and personal identity? This Research Topic provides an overview of potentials and limitations of deep brain stimulation as used to treat neurological and psychiatric conditions, bringing together Mini Reviews, Perspectives and Opinion papers from key stakeholders interested in the development and social impact of this technology. It is also a continuation of the debate that started among scientists, clinicians, patients, sociologists, journalists, philosophers and other experts during the “brains in dialogue on deep brain stimulation” workshop that was organized in September 2010 in Warsaw, Poland, by the FP7 project bid – brains in dialogue (www.neuromedia.eu) coordinated by the Interdisciplinary Laboratory of SISSA (Trieste, Italy).

Deep Brain Stimulation for Neurological Disorders

Deep Brain Stimulation for Neurological Disorders
Author: Toru Itakura
Publisher: Springer
Total Pages: 212
Release: 2014-08-28
Genre: Medical
ISBN: 3319084763

Chronic electrical stimulation of the brain has demonstrated excellent outcomes in patients with Parkinson’s disease and has recently also been applied to various other neurological diseases. This comprehensive, up-to-date textbook will meet the needs of all who wish to learn more about the application of deep brain stimulation and will provide a sound basis for safe and accurate surgery. The book comprises two main parts, the first of which presents relevant anatomical and functional background information on the basal ganglia, thalamus and other brain structures as well as on the mechanism of brain stimulation. The second part describes clinical studies on deep brain stimulation, covering results in a range of movement disorders and psychiatric diseases and also important aspects of instrumentation and technique. The authors are outstanding scientists and experts in the field from across the world.

The Pleasure Shock

The Pleasure Shock
Author: Lone Frank
Publisher: Penguin
Total Pages: 322
Release: 2018-03-20
Genre: Medical
ISBN: 1101986530

The electrifying, forgotten history of Robert Heath's brain pacemaker, investigating the origins and ethics of one of today's most promising medical breakthroughs: deep brain stimulation The technology invented by psychiatrist Robert G. Heath in the 1950s and '60s has been described as among the most controversial experiments in US history. His work was alleged at the time to be part of MKUltra, the CIA's notorious "mind control" project. His research subjects included incarcerated convicts and gay men who wished to be "cured" of their sexual preference. Yet his cutting-edge research and legacy were quickly buried deep in Tulane University's archives. Investigative science journalist Lone Frank now tells the complete sage of this passionate, determined doctor and his groundbreaking neuroscience. More than fifty years after Heath's experiments, this very same treatment is becoming mainstream practice in modern psychiatry for everything from schizophrenia, anorexia, and compulsive behavior to depression, Parkinson's, and even substance addiction. Lone Frank uncovered lost documents and accounts of Heath's trailblazing work. She tracked down surviving colleagues and patients, and she delved into the current support for deep brain stimulation by scientists and patients alike. What has changed? Why do we today unquestioningly embrace this technology as a cure? How do we decide what is a disease of the brain to be cured and what should be allowed to remain unrobed and unprodded? And how do we weigh the decades of criticism against the promise of treatment that could be offered to millions of patients? Elegantly written and deeply fascinating, The Pleasure Shock weaves together biography, scientific history, and medical ethics. It is an adventure into our ever-shifting views of the mind and the fateful power we wield when we tinker with the self.

20 Things to Know about Deep Brain Stimulation

20 Things to Know about Deep Brain Stimulation
Author: Erwin B. Montgomery (Jr.)
Publisher: Oxford University Press, USA
Total Pages: 297
Release: 2015
Genre: Medical
ISBN: 0199338825

An iconoclast in-depth analysis of the current understanding of DBS: efficacy, safety, indications, selection criteria and post-operative management. This book is an epistemic analysis of the presumptions, assumptions and fallacies. It provides the revolutionary potential and the complexity of DBS in changing healthcare delivery; the ethics are discussed in detail.

Fundamentals and Clinics of Deep Brain Stimulation

Fundamentals and Clinics of Deep Brain Stimulation
Author: Yasin Temel
Publisher: Springer Nature
Total Pages: 306
Release: 2020-03-24
Genre: Medical
ISBN: 3030363465

This book provides a state-of-the-art overview of our current understanding of deep brain stimulation (DBS) for the treatment of neurological and psychiatric disorders. With a broad multidisciplinary scope, it presents contributions from leading experts in the field from Europe and America, who share not only their knowledge, but their experience as well. The book focuses both on basic and theoretical aspects of DBS, as well as clinical and practical aspects. It follows an evidence-based approach, and where possible offers clinical recommendations based on published guidelines. It starts with a general section, which discusses basic principles and general considerations. This is followed a sections dedicated to neurological disorders, and psychiatric disorders, in which only accepted indications are discussed. All experimental indications are discussed in the final chapter. The text is supplemented with numerous illustrations. Intended for medical specialists and residents involved in the treatment of patients with DBS, it also appeals to other professionals working with DBS patients, such as psychologists, nurses, physiotherapists, as well as basic and clinical neuroscientists.

Deep Brain Stimulation Management

Deep Brain Stimulation Management
Author: William J. Marks, Jr
Publisher: Cambridge University Press
Total Pages: 251
Release: 2015-09-03
Genre: Medical
ISBN: 1107084253

Essential reference guide for clinicians working with DBS patients, fully revised throughout with new chapters on epilepsy and psychiatric disorders.

Deep Brain Stimulation

Deep Brain Stimulation
Author: Shilpa Chitnis MD, PhD
Publisher: Oxford University Press
Total Pages: 271
Release: 2020-06-30
Genre: Medical
ISBN: 0190647213

DEEP BRAIN STIMULATION provides expert advice to the reader on selection guidelines and programming techniques for straight-forward as well as for challenging case management in movement and neuropsychiatric disorders. The collection offers a broad DBS experience that is delivered directly to you by leaders in neuromodulation. There are both common and uncommon case presentations and each case is accompanied by a literature review and pearls to improve your practice. The book improves fundamental DBS techniques as well as expands the skills necessary for troubleshooting more difficult presentations. The case-based problem-solving approach makes this a fun and practical read.

Personalized Psychiatry

Personalized Psychiatry
Author: Bernhard Baune
Publisher: Academic Press
Total Pages: 594
Release: 2019-10-16
Genre: Medical
ISBN: 0128131772

Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. - Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics - Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry - Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective

Geriatric Forensic Psychiatry

Geriatric Forensic Psychiatry
Author: Jacob Holzer
Publisher: Oxford University Press
Total Pages: 409
Release: 2017-12-12
Genre: Medical
ISBN: 0199374651

This textbook, one of the first, provides a comprehensive review of the relationship between psychiatry and legal medicine in the older population. Sections reviewing evaluation, civil and criminal topics, and numerous other areas such as risk management, will help physicians, attorneys, and other professionals in their work with the elderly.