The Complex Connection between Cannabis and Schizophrenia

The Complex Connection between Cannabis and Schizophrenia
Author: Michael T. Compton
Publisher: Academic Press
Total Pages: 364
Release: 2017-08-25
Genre: Medical
ISBN: 0128051833

The Complex Connection between Cannabis and Schizophrenia provides an in-depth overview of the current state of research into the role that cannabis plays in schizophrenia, covering both the pathophysiological and the pharmacological implications. It addresses the epidemiology of cannabis use and the risks associated with its use, the biological aspects of the drug, its effects on the brain and the pharmacological possibilities of using cannabidiol to treat schizophrenia. It is the only book on the market devoted exclusively to examining the links between this very commonly used (and misused) drug and a specific set of devastating psychiatric illnesses, providing a comprehensive guide to our current understandings of this relationship. Marijuana is the most commonly used illicit drug globally, and is becoming increasingly decriminalized and even legalized worldwide. Among the numerous mental-health concerns related to the drug, there is mounting evidence of an intricate link between cannabis use and schizophrenia and related psychotic disorders. At the same time, there is promising evidence to suggest that cannabidiol, one of the many compounds found in cannabis that activates the brain’s cannabinoid receptors, could prove to be an effective antipsychotic to treat schizophrenia. Synthesizes existing knowledge about the confusing, but crucial, relationship between cannabis use and schizophrenia symptoms Provides a comprehensive overview of the neurobiological mechanisms of cannabis use and its effects on the brain, including an exploration of the endocannabinoid system Examines the promising evidence suggesting cannabidiol as an effective antipsychotic treatment for schizophrenia Aids readers studying the neurobiological underpinning of cannabis addiction and psychosis in determining directions for their own future research

The Health Effects of Cannabis and Cannabinoids

The Health Effects of Cannabis and Cannabinoids
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 487
Release: 2017-03-31
Genre: Science
ISBN: 0309453070

Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Marijuana and Madness

Marijuana and Madness
Author: David Castle
Publisher: Cambridge University Press
Total Pages: 238
Release: 2004-05-27
Genre: Medical
ISBN: 9781139451659

This book provides a comprehensive overview of the psychiatry and neuroscience of Cannabis sativa (marijuana), with particular emphasis on psychotic disorders. It outlines developments in our understanding of the human cannabinoid system, and links this knowledge to clinical and epidemiological facts about the impact of cannabis on mental health. Clinically focused chapters review not only the direct psychomimetic properties of cannabis, but also the impact consumption has on the courses of evolving or established mental illness such as schizophrenia. A number of controversial issues are critically explored, including whether a discrete 'cannabis psychosis' exists, and whether cannabis can actually cause schizophrenia. Effects of cannabis on mood, notably depression, are reviewed, as are its effects on cognition. This book will be of interest to all members of the mental health team, as well as to neuroscientists and those involved in drug and alcohol research.

Marijuana and Mental Health

Marijuana and Mental Health
Author: Michael T. Compton, M.D., M.P.H.
Publisher: American Psychiatric Pub
Total Pages: 258
Release: 2016-03-18
Genre: Medical
ISBN: 1615370080

With relatable clinical vignettes that illustrate the applicability of each chapter’s content, as well as key chapter points that summarize major themes, Marijuana and Mental Health is the definitive, single source of comprehensive information on marijuana and mental health in modern American society. Balanced, focused, and highly readable, chapters address topics such as the effects of marijuana on the brain and mind, marijuana-related policy and legislation, the complex link between marijuana use and psychotic disorders, synthetic cannabinoids, and the treatment and prevention of marijuana misuse. Beyond offering clinical and research psychiatrists, psychiatric residents and fellows, clinical psychologists, and psychiatric nurses a comprehensive but concise compilation of research in this area, this reference informs clinical mental health practice as well as policy decisions by articulating the connection between marijuana and mental health, particularly in the United States.

Tell Your Children

Tell Your Children
Author: Alex Berenson
Publisher: Free Press
Total Pages: 304
Release: 2020-02-18
Genre: Political Science
ISBN: 1982103671

In “a brilliant antidote to all the…false narratives about pot” (American Thinker), an award-winning author and former New York Times reporter reveals the link between teenage marijuana use and mental illness, and a hidden epidemic of violence caused by the drug—facts the media have ignored as the United States rushes to legalize cannabis. Recreational marijuana is now legal in nine states. Advocates argue cannabis can help everyone from veterans to cancer sufferers. But legalization has been built on myths—that marijuana arrests fill prisons; that most doctors want to use cannabis as medicine; that it can somehow stem the opiate epidemic; that it is beneficial for mental health. In this meticulously reported book, Alex Berenson, a former New York Times reporter, explodes those myths, explaining that almost no one is in prison for marijuana; a tiny fraction of doctors write most authorizations for medical marijuana, mostly for people who have already used; and marijuana use is linked to opiate and cocaine use. Most of all, THC—the chemical in marijuana responsible for the drug’s high—can cause psychotic episodes. “Alex Berenson has a reporter’s tenacity, a novelist’s imagination, and an outsider’s knack for asking intemperate questions” (Malcolm Gladwell, The New Yorker), as he ranges from the London institute that is home to the scientists who helped prove the cannabis-psychosis link to the Colorado prison where a man now serves a thirty-year sentence after eating a THC-laced candy bar and killing his wife. He sticks to the facts, and they are devastating. With the US already gripped by one drug epidemic, Tell Your Children is a “well-written treatise” (Publishers Weekly) that “takes a sledgehammer to the promised benefits of marijuana legalization, and cannabis enthusiasts are not going to like it one bit” (Mother Jones).

First Episode Psychosis

First Episode Psychosis
Author: Katherine J. Aitchison
Publisher: CRC Press
Total Pages: 152
Release: 1999-02-17
Genre: Medical
ISBN: 9781853174353

The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management.

Secondary Schizophrenia

Secondary Schizophrenia
Author: Perminder S. Sachdev
Publisher: Cambridge University Press
Total Pages:
Release: 2010-02-04
Genre: Medical
ISBN: 1139485229

Schizophrenia may not be a single disease, but the result of a diverse set of related conditions. Modern neuroscience is beginning to reveal some of the genetic and environmental underpinnings of schizophrenia; however, an approach less well travelled is to examine the medical disorders that produce symptoms resembling schizophrenia. This book is the first major attempt to bring together the diseases that produce what has been termed 'secondary schizophrenia'. International experts from diverse backgrounds ask the questions: does this medical disorder, or drug, or condition cause psychosis? If yes, does it resemble schizophrenia? What mechanisms form the basis of this relationship? What implications does this understanding have for aetiology and treatment? The answers are a feast for clinicians and researchers of psychosis and schizophrenia. They mark the next step in trying to meet the most important challenge to modern neuroscience – understanding and conquering this most mysterious of human diseases.

Marijuana and Medicine

Marijuana and Medicine
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 288
Release: 1999-07-10
Genre: Medical
ISBN: 0309071550

The medical use of marijuana is surrounded by a cloud of social, political, and religious controversy, which obscures the facts that should be considered in the debate. This book summarizes what we know about marijuana from evidence-based medicineâ€"the harm it may do and the relief it may bring to patients. The book helps the reader understand not only what science has to say about medical marijuana but also the logic behind the scientific conclusions. Marijuana and Medicine addresses the science base and the therapeutic effects of marijuana use for medical conditions such as glaucoma and multiple sclerosis. It covers marijuana's mechanism of action, acute and chronic effects on health and behavior, potential adverse effects, efficacy of different delivery systems, analysis of the data about marijuana as a gateway drug, and the prospects for developing cannabinoid drugs. The book evaluates how well marijuana meets accepted standards for medicine and considers the conclusions of other blue-ribbon panels. Full of useful facts, this volume will be important to anyone interested in informed debate about the medical use of marijuana: advocates and opponents as well as policymakers, regulators, and health care providers.

Marijuana and Madness

Marijuana and Madness
Author: Deepak Cyril D'Souza
Publisher: Cambridge University Press
Total Pages: 379
Release: 2023-06-01
Genre: Medical
ISBN: 1108944000

An updated third edition of this award-winning book provides a comprehensive overview of the complex associations between cannabis and mental illness. Organised into easy to navigate sections, the book has been fully revised to feature eight entirely new chapters covering important novel aspects. Marijuana and Madness incorporates new research findings on the potential use of cannabinoids, and synthetic cannabinoids, in an array of mental illnesses, balanced against the potential adverse effects. The associations between cannabis and psychosis, developing putative models of 'cannabis induced' psychosis and pathways to schizophrenia are all covered. The book importantly discusses the impact of exposure to cannabis at various stages of neurodevelopment (in utero, in childhood, and during adolescence) and it thoroughly reviews the treatments for cannabis dependence and health policy implications of the availability of increasingly high potency cannabis. This book will quickly become an essential resource for all members of the mental health team.

American Psychosis

American Psychosis
Author: E. Fuller Torrey
Publisher: Oxford University Press
Total Pages: 219
Release: 2013-08-22
Genre: Psychology
ISBN: 0199361126

In 1963, President John F. Kennedy delivered an historic speech on mental illness and retardation. He described sweeping new programs to replace "the shabby treatment of the many millions of the mentally disabled in custodial institutions" with treatment in community mental health centers. This movement, later referred to as "deinstitutionalization," continues to impact mental health care. Though he never publicly acknowledged it, the program was a tribute to Kennedy's sister Rosemary, who was born mildly retarded and developed a schizophrenia-like illness. Terrified she'd become pregnant, Joseph Kennedy arranged for his daughter to receive a lobotomy, which was a disaster and left her severely retarded. Fifty years after Kennedy's speech, E. Fuller Torrey's book provides an inside perspective on the birth of the federal mental health program. On staff at the National Institute of Mental Health when the program was being developed and implemented, Torrey draws on his own first-hand account of the creation and launch of the program, extensive research, one-on-one interviews with people involved, and recently unearthed audiotapes of interviews with major figures involved in the legislation. As such, this book provides historical material previously unavailable to the public. Torrey examines the Kennedys' involvement in the policy, the role of major players, the responsibility of the state versus the federal government in caring for the mentally ill, the political maneuverings required to pass the legislation, and how closing institutions resulted not in better care - as was the aim - but in underfunded programs, neglect, and higher rates of community violence. Many now wonder why public mental illness services are so ineffective. At least one-third of the homeless are seriously mentally ill, jails and prisons are grossly overcrowded, largely because the seriously mentally ill constitute 20 percent of prisoners, and public facilities are overrun by untreated individuals. As Torrey argues, it is imperative to understand how we got here in order to move forward towards providing better care for the most vulnerable.