Finite Mixture Models

Finite Mixture Models
Author: Geoffrey McLachlan
Publisher: John Wiley & Sons
Total Pages: 419
Release: 2004-03-22
Genre: Mathematics
ISBN: 047165406X

An up-to-date, comprehensive account of major issues in finitemixture modeling This volume provides an up-to-date account of the theory andapplications of modeling via finite mixture distributions. With anemphasis on the applications of mixture models in both mainstreamanalysis and other areas such as unsupervised pattern recognition,speech recognition, and medical imaging, the book describes theformulations of the finite mixture approach, details itsmethodology, discusses aspects of its implementation, andillustrates its application in many common statisticalcontexts. Major issues discussed in this book include identifiabilityproblems, actual fitting of finite mixtures through use of the EMalgorithm, properties of the maximum likelihood estimators soobtained, assessment of the number of components to be used in themixture, and the applicability of asymptotic theory in providing abasis for the solutions to some of these problems. The author alsoconsiders how the EM algorithm can be scaled to handle the fittingof mixture models to very large databases, as in data miningapplications. This comprehensive, practical guide: * Provides more than 800 references-40% published since 1995 * Includes an appendix listing available mixture software * Links statistical literature with machine learning and patternrecognition literature * Contains more than 100 helpful graphs, charts, and tables Finite Mixture Models is an important resource for both applied andtheoretical statisticians as well as for researchers in the manyareas in which finite mixture models can be used to analyze data.

Discriminant Analysis and Statistical Pattern Recognition

Discriminant Analysis and Statistical Pattern Recognition
Author: Geoffrey J. McLachlan
Publisher: John Wiley & Sons
Total Pages: 553
Release: 2005-02-25
Genre: Mathematics
ISBN: 0471725285

The Wiley-Interscience Paperback Series consists of selected books that have been made more accessible to consumers in an effort to increase global appeal and general circulation. With these new unabridged softcover volumes, Wiley hopes to extend the lives of these works by making them available to future generations of statisticians, mathematicians, and scientists. "For both applied and theoretical statisticians as well as investigators working in the many areas in which relevant use can be made of discriminant techniques, this monograph provides a modern, comprehensive, and systematic account of discriminant analysis, with the focus on the more recent advances in the field." –SciTech Book News ". . . a very useful source of information for any researcher working in discriminant analysis and pattern recognition." –Computational Statistics Discriminant Analysis and Statistical Pattern Recognition provides a systematic account of the subject. While the focus is on practical considerations, both theoretical and practical issues are explored. Among the advances covered are regularized discriminant analysis and bootstrap-based assessment of the performance of a sample-based discriminant rule, and extensions of discriminant analysis motivated by problems in statistical image analysis. The accompanying bibliography contains over 1,200 references.

The EM Algorithm and Extensions

The EM Algorithm and Extensions
Author: Geoffrey J. McLachlan
Publisher: John Wiley & Sons
Total Pages: 399
Release: 2007-11-09
Genre: Mathematics
ISBN: 0470191600

The only single-source——now completely updated and revised——to offer a unified treatment of the theory, methodology, and applications of the EM algorithm Complete with updates that capture developments from the past decade, The EM Algorithm and Extensions, Second Edition successfully provides a basic understanding of the EM algorithm by describing its inception, implementation, and applicability in numerous statistical contexts. In conjunction with the fundamentals of the topic, the authors discuss convergence issues and computation of standard errors, and, in addition, unveil many parallels and connections between the EM algorithm and Markov chain Monte Carlo algorithms. Thorough discussions on the complexities and drawbacks that arise from the basic EM algorithm, such as slow convergence and lack of an in-built procedure to compute the covariance matrix of parameter estimates, are also presented. While the general philosophy of the First Edition has been maintained, this timely new edition has been updated, revised, and expanded to include: New chapters on Monte Carlo versions of the EM algorithm and generalizations of the EM algorithm New results on convergence, including convergence of the EM algorithm in constrained parameter spaces Expanded discussion of standard error computation methods, such as methods for categorical data and methods based on numerical differentiation Coverage of the interval EM, which locates all stationary points in a designated region of the parameter space Exploration of the EM algorithm's relationship with the Gibbs sampler and other Markov chain Monte Carlo methods Plentiful pedagogical elements—chapter introductions, lists of examples, author and subject indices, computer-drawn graphics, and a related Web site The EM Algorithm and Extensions, Second Edition serves as an excellent text for graduate-level statistics students and is also a comprehensive resource for theoreticians, practitioners, and researchers in the social and physical sciences who would like to extend their knowledge of the EM algorithm.

Linear Models

Linear Models
Author: Shayle R. Searle
Publisher: John Wiley & Sons
Total Pages: 565
Release: 1997-03-28
Genre: Mathematics
ISBN: 0471184993

This 1971 classic on linear models is once again available--as a Wiley Classics Library Edition. It features material that can be understood by any statistician who understands matrix algebra and basic statistical methods.

Analyzing Microarray Gene Expression Data

Analyzing Microarray Gene Expression Data
Author: Geoffrey J. McLachlan
Publisher: John Wiley & Sons
Total Pages: 366
Release: 2005-02-18
Genre: Mathematics
ISBN: 0471726125

A multi-discipline, hands-on guide to microarray analysis of biological processes Analyzing Microarray Gene Expression Data provides a comprehensive review of available methodologies for the analysis of data derived from the latest DNA microarray technologies. Designed for biostatisticians entering the field of microarray analysis as well as biologists seeking to more effectively analyze their own experimental data, the text features a unique interdisciplinary approach and a combined academic and practical perspective that offers readers the most complete and applied coverage of the subject matter to date. Following a basic overview of the biological and technical principles behind microarray experimentation, the text provides a look at some of the most effective tools and procedures for achieving optimum reliability and reproducibility of research results, including: An in-depth account of the detection of genes that are differentially expressed across a number of classes of tissues Extensive coverage of both cluster analysis and discriminant analysis of microarray data and the growing applications of both methodologies A model-based approach to cluster analysis, with emphasis on the use of the EMMIX-GENE procedure for the clustering of tissue samples The latest data cleaning and normalization procedures The uses of microarray expression data for providing important prognostic information on the outcome of disease

Mixture Model-Based Classification

Mixture Model-Based Classification
Author: Paul D. McNicholas
Publisher: CRC Press
Total Pages: 212
Release: 2016-10-04
Genre: Mathematics
ISBN: 1482225670

"This is a great overview of the field of model-based clustering and classification by one of its leading developers. McNicholas provides a resource that I am certain will be used by researchers in statistics and related disciplines for quite some time. The discussion of mixtures with heavy tails and asymmetric distributions will place this text as the authoritative, modern reference in the mixture modeling literature." (Douglas Steinley, University of Missouri) Mixture Model-Based Classification is the first monograph devoted to mixture model-based approaches to clustering and classification. This is both a book for established researchers and newcomers to the field. A history of mixture models as a tool for classification is provided and Gaussian mixtures are considered extensively, including mixtures of factor analyzers and other approaches for high-dimensional data. Non-Gaussian mixtures are considered, from mixtures with components that parameterize skewness and/or concentration, right up to mixtures of multiple scaled distributions. Several other important topics are considered, including mixture approaches for clustering and classification of longitudinal data as well as discussion about how to define a cluster Paul D. McNicholas is the Canada Research Chair in Computational Statistics at McMaster University, where he is a Professor in the Department of Mathematics and Statistics. His research focuses on the use of mixture model-based approaches for classification, with particular attention to clustering applications, and he has published extensively within the field. He is an associate editor for several journals and has served as a guest editor for a number of special issues on mixture models.

Handbook of Computational Statistics

Handbook of Computational Statistics
Author: Yuichi Mori
Publisher: Springer Science & Business Media
Total Pages: 1096
Release: 2004-07-14
Genre: Computers
ISBN: 9783540404644

The Handbook of Computational Statistics: Concepts and Methodology is divided into four parts. It begins with an overview over the field of Computational Statistics. The second part presents several topics in the supporting field of statistical computing. Emphasis is placed on the need of fast and accurate numerical algorithms and it discusses some of the basic methodologies for transformation, data base handling and graphics treatment. The third part focuses on statistical methodology. Special attention is given to smoothing, iterative procedures, simulation and visualization of multivariate data. Finally a set of selected applications like Bioinformatics, Medical Imaging, Finance and Network Intrusion Detection highlight the usefulness of computational statistics.

Mathematical, Computational and Experimental T Cell Immunology

Mathematical, Computational and Experimental T Cell Immunology
Author: Carmen Molina-París
Publisher: Springer Nature
Total Pages: 300
Release: 2021-01-04
Genre: Medical
ISBN: 3030572048

Mathematical, statistical, and computational methods enable multi-disciplinary approaches that catalyse discovery. Together with experimental methods, they identify key hypotheses, define measurable observables and reconcile disparate results. This volume collects a representative sample of studies in T cell immunology that illustrate the benefits of modelling-experimental collaborations and which have proven valuable or even ground-breaking. Studies include thymic selection, T cell repertoire diversity, T cell homeostasis in health and disease, T cell-mediated immune responses, T cell memory, T cell signalling and analysis of flow cytometry data sets. Contributing authors are leading scientists in the area of experimental, computational, and mathematical immunology. Each chapter includes state-of-the-art and pedagogical content, making this book accessible to readers with limited experience in T cell immunology and/or mathematical and computational modelling.

The Top Ten Algorithms in Data Mining

The Top Ten Algorithms in Data Mining
Author: Xindong Wu
Publisher: CRC Press
Total Pages: 230
Release: 2009-04-09
Genre: Business & Economics
ISBN: 142008965X

Identifying some of the most influential algorithms that are widely used in the data mining community, The Top Ten Algorithms in Data Mining provides a description of each algorithm, discusses its impact, and reviews current and future research. Thoroughly evaluated by independent reviewers, each chapter focuses on a particular algorithm and is wri