Immunosuppression in Inflammatory Bowel Diseases

Immunosuppression in Inflammatory Bowel Diseases
Author: K. Fellermann
Publisher: Springer Science & Business Media
Total Pages: 288
Release: 2001-06-30
Genre: Medical
ISBN: 9780792387671

The aetiology of the chronic inflammatory bowel diseases - Crohn's disease and ulcerative colitis - is still enigmatic. The therapeutic approach has therefore traditionally focused on anti-inflammatory principles, including corticosteroids and aminosalicylates. Since a significant proportion of patients is steroid-dependent or refractory and because of the problematic side-effects of long-term systemic steroids, active immunosuppression has gained acceptance in the field. The classical immunosuppressants azathioprine and 6-mercaptopurine have long been evidence-based in IBD, but underused. Recently, methotrexate and cyclosporine have also been proven to be effective in certain situations. Newer drugs like tacrolimus, mycophenolate and others may be similarly useful but their potential is still unclear. Finally, the immune modifiers including IL-10 and TNF-antibodies have been successfully subjected to controlled trials. Other experimental drugs discussed in this book are on the horizon. This volume is the Proceedings of Falk Symposium 119 held in Freiburg-im-Breisgau, Germany, October 3-4, 2000, and covers systematically the field of immunosuppression in inflammatory bowel diseases. It is hoped that it will further the prudent use of these drugs in the proper clinical situations by increasing our understanding of both the mechanisms of action and the clinical benefit to the patient.

Psychological Aspects of Inflammatory Bowel Disease

Psychological Aspects of Inflammatory Bowel Disease
Author: Simon R. Knowles
Publisher: Routledge
Total Pages: 253
Release: 2014-09-19
Genre: Psychology
ISBN: 1317807383

In the Western world around 360 in every 100,000 individuals have inflammatory bowel disease (IBD), a relapsing-remitting autoimmune disease that affects the gastrointestinal tract. Its impact on individual functioning across physical and psychosocial domains is significant and psychological distress is a common feature, with research suggesting that active IBD is associated with one of the highest rates of depression and anxiety of all chronic illnesses. Despite the high prevalence of mental health co-morbidities in IBD, psychological illness remains largely undertreated, with studies showing that 60% of IBD patients experiencing mental health problems do not receive adequate help. In this book, Knowles and Mikocka-Walus bring together world experts who practice integrated and holistic approach in their care for IBD patients, to provide an overview of research across a range of topics associated with the biopsychosocial treatment of IBD. Each chapter provides an up-to-date comprehensive consolidation and evaluation of the current literature alongside recommendations for practice. Key themes include: current understanding of the interrelationship of the neurological and biological aspects of IBD common concerns and issues individuals with IBD face exploring challenges across individual life-stages current evidence for psychosocial interventions recommendations for future directions of biopsychosocial work. Psychological Aspects of Inflammatory Bowel Disease: A biopsychosocial approach is a key resource for researchers, practitioners and academics considering psychosocial aspects of the disease and psychological interventions. It will also appeal to health psychologists and mental health practitioners working with clients with IBD, as well as gastroenterologists interested in a comprehensive and holistic approach to IBD management.

Your Child with Inflammatory Bowel Disease

Your Child with Inflammatory Bowel Disease
Author: North American Society for Pediatric Gastroenterology, Hepatology and Nutrition
Publisher: JHU Press
Total Pages: 304
Release: 2010-06-10
Genre: Family & Relationships
ISBN: 0801895553

When a child has inflammatory bowel disease, the family has many concerns: Why is my child sick? What can we do to help him get better? What does the future hold for her? In this book, an expert team of pediatric gastroenterologists explains the symptoms, diagnoses, and treatments associated with Crohn disease, ulcerative colitis, and indeterminate colitis to help parents and children cope with the challenges of IBD. The authors' empathy and experience are evident throughout as they answer such questions as: • What are inflammatory bowel disease, Crohn disease, and ulcerative colitis?• Is there a cure for IBD?• How is IBD going to affect my child's daily life?• Will my child's diet change?• Can my child still play sports?• Will my child need surgery?• What are the side effects of commonly prescribed medications? The book also provides parents with practical advice on how to tell their children about their IBD and discusses the challenges children may face at school and in their social lives, especially as they grow older. Additional information on IBD medications, complementary treatments, and further reading round out this comprehensive and reliable resource.

Biomarkers in Inflammatory Bowel Diseases

Biomarkers in Inflammatory Bowel Diseases
Author: Nik Sheng Ding
Publisher: Springer
Total Pages: 355
Release: 2019-05-13
Genre: Medical
ISBN: 3030114465

This book provides a comprehensive and complete overview of biomarkers in clinical practice for inflammatory bowel disease (IBD) bringing together the literature in a clear and concise manner. The book bridges the gap between growing knowledge at the bench and current and future applications of biomarkers in clinical practice. The central structure of the book focuses on prognostic and predictive biomarkers in IBD with an emphasis on the fields of research and scientific techniques (genomics, proteomics and metabonomics) that have led to biomarker discovery and places these biomarkers within a clinical context to help understand their utility in clinical practice. This book will be of use to clinicians who have an interest in using biomarkers in clinical practice as well as clinician researchers and scientists involved in the biomarker research pipeline. The author team comprises experts from around the world in order to bring together the literature in an effort to inform clinicians and researchers about the current state-of-the art in biomarker discovery. It is intended to assist future research efforts and indicate how biomarkers might be best applied to clinical practice both at present and in the future.

Pediatric Inflammatory Bowel Disease

Pediatric Inflammatory Bowel Disease
Author: Petar Mamula
Publisher: Springer Science & Business Media
Total Pages: 573
Release: 2012-12-14
Genre: Medical
ISBN: 1461450616

Pediatric Inflammatory Bowel Disease, Second Edition provides an essential reference with an emphasis on the unique pediatric issues of IBD. Chapters focus on complications of IBD specific to children and adolescents. Treatment recommendations are based on the latest clinical research available. The textbook also presents sections dedicated to the aspects of participation in clinical research unique to children and adolescents and the complicated yet vital process of successfully transitioning a patient from a pediatric to adult specialist. Controversies in pediatric IBD care such as the off-label use of medications are also covered. The format incorporates multiple tables, graphs, and figures to improve readability and make for an efficient reference for clinicians to use. Thoroughly revised and updated from the first edition, the volumes includes new therapies that are currently being used or tested for treatment of IBD, important areas regarding incidence and prevalence, immunization and response to vaccine administration as well as advancements in our understanding of growth and development with particular to the use of growth hormone therapy. Other new areas covered include important topics of complementary and alternative medicine use in IBD, immunization, and liver disease in IBD. Pediatric Inflammatory Bowel Disease, Second Edition is a valuable resource for pediatric gastroenterologists as well as adult gastroenterologists.

IBD And You: Navigating the Challenges of Inflammatory Bowel Disease

IBD And You: Navigating the Challenges of Inflammatory Bowel Disease
Author: Ethan D. Anderson
Publisher: BornIncredible.com
Total Pages: 380
Release: 2023-01-01
Genre: Health & Fitness
ISBN: 1776969596

"Knowledge is power when it comes to managing IBD." Are you or a loved one living with Inflammatory Bowel Disease (IBD)? Don't let the overwhelming nature of this chronic illness define your life. Discover the tools, resources, and insights you need to take control of your condition in "IBD And You: Navigating the Challenges of Inflammatory Bowel Disease." With comprehensive information on the causes, symptoms, and treatments for IBD, this book serves as a guide to help you understand the ins and outs of Crohn's Disease, Ulcerative Colitis, and other related conditions. Delve into the impact of diet, stress, and gut microbiota on IBD, and learn about the importance of mental health in managing the disease. Explore various medical treatments and alternative therapies, and discover how to create a personalized plan for managing your symptoms. Understand the risks and complications associated with IBD, and read inspiring stories from people who have successfully navigated the challenges of living with this condition. In addition to offering expert advice on managing IBD in various stages of life, this book provides practical tips for travel, work, and relationships. Gain knowledge about the diagnostic process, clinical trials, and the future of IBD treatment, all while finding hope and support within the IBD community. Whether you're a patient, caregiver, or healthcare provider, "IBD And You" offers valuable insights and practical strategies for managing the complex challenges of IBD. Table of Contents Introduction What is a IBD? Epidemiology And Demographics Global Prevalence Of IBD Age And Gender Distribution Regional Differences And Trends Pathophysiology Mucosal Inflammation And Ulceration Crohn's Disease Vs. Ulcerative Colitis: Differences In Inflammation Patterns Role Of Cytokines And Inflammatory Mediators How do you get IBD The Types of Inflammatory Bowel Disease Crohn's Disease Ulcerative Colitis Indeterminate Colitis Differences between Crohn's Disease and Ulcerative Colitis: The Impact of Inflammatory Bowel Disease on Daily Life Causes And Risk Factors Genetic Factors Environmental Factors Microbial Factors Immune System Dysregulation What are the symptoms of IBD Symptoms of Inflammatory Bowel Disease Common Symptoms of Inflammatory Bowel Disease Understanding the Severity of Inflammatory Bowel Disease How to Monitor Your Symptoms Symptoms And Clinical Presentation Common Symptoms Of IBD Differences Between Crohn's Disease And Ulcerative Colitis Extraintestinal Manifestations Diagnosis And Evaluation Blood Tests Endoscopy And Imaging Biopsies Differential Diagnoses Psychological And Emotional Impact Mental Health In IBD Patients Coping Strategies And Support Networks The Importance Of Addressing Mental Health In IBD Management What causes Inflammatory Bowel Disease? Genetic Factors and Inflammatory Bowel Disease Environmental Factors and Inflammatory Bowel Disease Other Possible Causes of Inflammatory Bowel Disease How can Inflammatory bowel disease be prevented? Potential Prevention Strategies And Early Interventions How is Inflammatory bowel disease diagnosed? The Diagnostic Process for Inflammatory Bowel Disease The Role of Medical Tests in Diagnosing Inflammatory Bowel Disease What to Expect During a Diagnosis Medical treatments for IBD Treatment Options for Inflammatory Bowel Disease Medications for Inflammatory Bowel Disease Dietary Changes for Inflammatory Bowel Disease Surgical Options for Inflammatory Bowel Disease Alternative treatments for IBD Lifestyle Changes for Inflammatory Bowel Disease Exercise and Inflammatory Bowel Disease Sleep and Inflammatory Bowel Disease Acupuncture and Inflammatory Bowel Disease Herbal Remedies for Inflammatory Bowel Disease Mind-Body Therapies for Inflammatory Bowel Disease The role of diet in IBD Nutritional Deficiencies In IBD Patients The Impact Of Diet On Symptoms And Disease Activity Common Dietary Recommendations And Considerations Nutrition and Inflammatory Bowel Disease The Relationship Between Nutrition and Inflammatory Bowel Disease Creating a Healthy Diet Plan for Inflammatory Bowel Disease Nutritional Supplements for Inflammatory Bowel Disease The role of stress in IBD Stress Management and Inflammatory Bowel Disease The role of gut microbiota in IBD The Gut Microbiome And Its Role In IBD Anatomy And Physiology Of The Gastrointestinal Tract Structure And Function Of The Gi Tract Role Of The Immune System In Gut Health What are the risks and complications associated with IBD? Inflammatory Bowel Disease and Mental Health The Relationship Between Inflammatory Bowel Disease and Mental Health Coping Strategies for Managing Anxiety and Depression When to Seek Professional Help for Mental Health Concerns Inflammatory Bowel Disease and Relationships Navigating Intimacy with Inflammatory Bowel Disease Managing Social Life with Inflammatory Bowel Disease Communicating with Loved Ones About Inflammatory Bowel Disease Inflammatory Bowel Disease and Work Navigating Work with Inflammatory Bowel Disease Understanding Your Rights as an Employee with Inflammatory Bowel Disease Communicating with Your Employer About Inflammatory Bowel Disease Inflammatory Bowel Disease and Pregnancy Understanding the Risks of Pregnancy with Inflammatory Bowel Disease Managing Your Condition During Pregnancy Planning for Your Baby's Health with Inflammatory Bowel Disease Inflammatory Bowel Disease and Travel Tips for Managing Inflammatory Bowel Disease While Traveling Preparing for Travel with Inflammatory Bowel Disease Communicating Your Needs While Traveling with Inflammatory Bowel Disease Inflammatory Bowel Disease and Children Understanding Pediatric Inflammatory Bowel Disease How to Talk to Your Child About Inflammatory Bowel Disease Coping Strategies for Parents of Children with Inflammatory Bowel Disease Inflammatory Bowel Disease and Aging Understanding the Effects of Aging on Inflammatory Bowel Disease Coping Strategies for Managing Inflammatory Bowel Disease in Later Life Communicating with Your Doctor About Inflammatory Bowel Disease and Aging Inflammatory Bowel Disease and Cancer Understanding the Link Between Inflammatory Bowel Disease and Cancer Managing Your Risk of Cancer with Inflammatory Bowel Disease Screening for Cancer with Inflammatory Bowel Disease Inflammatory Bowel Disease and Clinical Trials Understanding Clinical Trials for Inflammatory Bowel Disease How to Participate in Clinical Trials for Inflammatory Bowel Disease The Future of Inflammatory Bowel Disease Treatment Inflammatory Bowel Disease Support and Resources Finding Support for Inflammatory Bowel Disease Resources for Coping with Inflammatory Bowel Disease Advocating for Inflammatory Bowel Disease Awareness and Research Current Research And Future Directions Advances In IBD Genetics And Personalized Medicine Emerging Therapies And Interventions Living with Inflammatory Bowel Disease Managing Flares of Inflammatory Bowel Disease Understanding Flares of Inflammatory Bowel Disease Coping Strategies for Managing Flares When to Seek Medical Attention for Flares Strategies for Living Your Best Life with Inflammatory Bowel Disease The Importance of Self-Care with Inflammatory Bowel Disease Finding Hope and Support in the Inflammatory Bowel Disease Community. Sophie's Story Ella's Story Oliver's Story Lila's Story Sophie's Story Nate's Story Avery's Story Oliver's Story Emma's Story Sophie's Story Megan's Story Julia's Story Sophie's Story Frequently Asked Questions What are the symptoms of inflammatory bowel disease? What is the most common cause of inflammatory bowel disease? What happens when you have inflammatory bowel disease? Is inflammatory bowel disease serious? How do you fix bowel inflammation? Which is the most prominent signs of inflammatory bowel disease? How do you diagnose inflammatory bowel disease? Can you get rid of inflammatory bowel disease? How long can you live with inflammatory bowel disease? Does IBD get worse if untreated? Where is the pain with inflammatory bowel disease? Who gets inflammatory bowel disease? What is the difference between IBD and IBS? What causes inflammatory bowel disease flare ups? How do you know if you have bowel disease? What foods to avoid with IBD? What foods cause bowel inflammation? Does colitis always show up on colonoscopy? Does IBD show up in blood tests? Can IBD come on suddenly? When does inflammatory bowel disease start? Does IBD get worse with age? Is inflammatory bowel disease cancerous? Can you have normal poop with IBD? Does IBD always need surgery? What are likely symptoms of IBD? Is IBD a serious disease? Is IBD can be cured? How is IBD diagnosed? What foods can trigger IBD? What can trigger IBD? How long you can live with IBD? Is IBD a terminal illness? Is IBD the same as Crohn's disease? What happens if IBD is not treated? Would IBD show up in blood test? What can be mistaken for IBD? What does early IBD feel like? Is IBD triggered by stress? Can you get IBD from stress? What should people with IBD avoid? What's the difference between IBS and IBD? Is IBD worse than IBS? Do people with IBD need surgery? Is IBD genetic? Does IBD qualify for disability? Does IBD always show on colonoscopy? Can IBD be diagnosed without a colonoscopy? How many times do you poop with IBD? Can IBD be cured with diet? What is the main cause of Crohn's disease? What are the early warning signs of Crohn's disease? What can happen if you have Crohn's disease? Can Crohn's disease go away? What foods trigger Crohn's? How can I test myself for Crohn's? How do you detect Crohn's? How do they test for Crohn's? How long do people with Crohn's live? Can you drink alcohol with Crohn's disease? What do Crohn's pains feel like? Who is most likely to get Crohn's disease? What happens if you ignore Crohn's? What age does Crohns start? What are 5 symptoms of Crohn's disease? What is a good diet for Crohn's disease? Can you heal Crohn's with diet? Can you suddenly get Crohn's? What to avoid if you have Crohn's? What should people with Crohn's avoid? Would Crohns show up on a blood test? Can you see Crohns on a blood test? Will a colonoscopy detect Crohn's? What is the difference between Crohn's and colitis? What is the main cause of Crohn's Disease? What are the warning signs of Crohn's Disease? What should people with ulcerative colitis avoid? Can you see ulcerative colitis on a blood test? Will a colonoscopy detect ulcerative colitis's? What is the main cause of ulcerative colitis? What are the warning signs of ulcerative colitis? Does ulcerative colitis go away? What Food Triggers colitis? Who is most likely to get ulcerative colitis? How do you make ulcerative colitis go away? Do you poop a lot with ulcerative colitis? What is ulcerative colitis poop like? What can trigger an ulcerative colitis flare up? What is last stage of ulcerative colitis? Does colitis get worse with age? What's the difference between colitis and ulcerative colitis? How do you stop colitis inflammation? What color is colitis poop? What happens if you ignore ulcerative colitis? Is ulcerative colitis serious? Have Questions / Comments?

Crohn's Disease and Ulcerative Colitis

Crohn's Disease and Ulcerative Colitis
Author: Daniel C. Baumgart
Publisher: Springer
Total Pages: 671
Release: 2017-03-01
Genre: Medical
ISBN: 3319337033

This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex immunomodulatory principles. The latest edition also includes revised chapters from the previous edition, as well as new chapters reflecting current developments in the field. Written by experts in their field, Crohn’s Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach, Second Edition is of great value to gastroenterologists, surgeons, internists, pediatricians and gynecologists trainees, as well as all those involved in Crohn’s disease, ulcerative colitis, and related autoimmune disorders.