The Analysis of Regulatory DNA: Current Developments, Knowledge and Applications Uncovering Gene Regulation

The Analysis of Regulatory DNA: Current Developments, Knowledge and Applications Uncovering Gene Regulation
Author: Kenneth Berendzen
Publisher: Bentham Science Publishers
Total Pages: 225
Release: 2013-10-29
Genre: Science
ISBN: 1608054926

A major goal of integrative research is understanding regulatory networks to such an extent as to allow researchers to model developmental and stress responses. Regulatory networks of living systems include complex and vast interactions between proteins, metabolites, RNA, various signaling molecules and DNA. One aspect of systems biology is understanding the dynamics of protein-DNA interactions affecting gene expression that are caused by transcription factors (TFs) and chromatin remodeling factors. This e-book provides a resource for summarizing current knowledge eukaryotic transcription and explores cis-elements and methods for their analysis, prediction and discovery. The book also presents an overview of exploring gene regulatory networks, chromatin, and miRNAs. Information about state-of-the-art techniques for the determination of TF - cis-element interactions in vivo and in silico give cutting edge insights on how genomic-scale research is being approached. The Analysis of Regulatory DNA provides readers with both the necessary background knowledge and provocative, up-to-date insights aimed at sparking new and vibrant experimental designs for understanding and predicting cis-elements in the eukaryotic genome.

Artificial Intelligence: Theories, Models and Applications

Artificial Intelligence: Theories, Models and Applications
Author: John Darzentas
Publisher: Springer
Total Pages: 457
Release: 2008-09-22
Genre: Computers
ISBN: 3540878815

Artificial intelligence (AI) is a dynamic field that is constantly expanding into new application areas, discovering new research challenges and facilitating the devel- ment of innovative products. Today’s information overload and rapid technological advancement raise needs for effective management of the complexity and heteroge- ity of knowledge, for intelligent and adaptable man–machine interfaces and for pr- ucts and applications that can learn and take decisions by themselves. Although the mystery of human-level intelligence has just started to be uncovered in various int- disciplinary fields, AI is inspired by the respective scientific areas to explore certain theories and models that will provide the methods and techniques to design and - velop human-centered applications that address the above-mentioned needs. This volume contains papers selected for presentation at the 5th Hellenic Conference on Artificial Intelligence (SETN 2008), the official meeting of the Hellenic Society for Artificial Intelligence (EETN). Previous conferences were held at the University of Piraeus (1996), at the Aristotle University of Thessaloniki (2002), at the University of the Aegean (2004) and at the Institute of Computer Science at FORTH (Foundation for Research and Technology - Hellas) and the University of Crete (2006).

Database Systems for Advanced Applications

Database Systems for Advanced Applications
Author: Sang-goo Lee
Publisher: Springer
Total Pages: 615
Release: 2012-04-05
Genre: Computers
ISBN: 3642290388

This two volume set LNCS 7238 and LNCS 7239 constitutes the refereed proceedings of the 17th International Conference on Database Systems for Advanced Applications, DASFAA 2012, held in Busan, South Korea, in April 2012. The 44 revised full papers and 8 short papers presented together with 2 invited keynote papers, 8 industrial papers, 8 demo presentations, 4 tutorials and 1 panel paper were carefully reviewed and selected from a total of 159 submissions. The topics covered are query processing and optimization, data semantics, XML and semi-structured data, data mining and knowledge discovery, privacy and anonymity, data management in the Web, graphs and data mining applications, temporal and spatial data, top-k and skyline query processing, information retrieval and recommendation, indexing and search systems, cloud computing and scalability, memory-based query processing, semantic and decision support systems, social data, data mining.

Animal Biotechnology

Animal Biotechnology
Author: Ashish S. Verma
Publisher: Academic Press
Total Pages: 685
Release: 2013-11-04
Genre: Science
ISBN: 0123914345

Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field.Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences. - Highlights the latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseases - Provides firsthand accounts of the use of biotechnology tools, including molecular markers, stem cells, and tissue engineering

Applying Machine Learning Techniques to Bioinformatics: Few-Shot and Zero-Shot Methods

Applying Machine Learning Techniques to Bioinformatics: Few-Shot and Zero-Shot Methods
Author: Lilhore, Umesh Kumar
Publisher: IGI Global
Total Pages: 418
Release: 2024-03-22
Genre: Computers
ISBN:

Why are cutting-edge data science techniques such as bioinformatics, few-shot learning, and zero-shot learning underutilized in the world of biological sciences?. In a rapidly advancing field, the failure to harness the full potential of these disciplines limits scientists’ ability to unlock critical insights into biological systems, personalized medicine, and biomarker identification. This untapped potential hinders progress and limits our capacity to tackle complex biological challenges. The solution to this issue lies within the pages of Applying Machine Learning Techniques to Bioinformatics. This book serves as a powerful resource, offering a comprehensive analysis of how these emerging disciplines can be effectively applied to the realm of biological research. By addressing these challenges and providing in-depth case studies and practical implementations, the book equips researchers, scientists, and curious minds with the knowledge and techniques needed to navigate the ever-changing landscape of bioinformatics and machine learning within the biological sciences.

IASLC Thoracic Oncology E-Book

IASLC Thoracic Oncology E-Book
Author: Harvey Pass
Publisher: Elsevier Health Sciences
Total Pages: 904
Release: 2017-04-21
Genre: Medical
ISBN: 0323527841

Global experts, in conjunction with the International Association for the Study of Lung Cancer, bring you up to date with today's best approaches to lung cancer diagnosis, treatment, and follow-up. IASLC Thoracic Oncology, 2nd Edition, keeps you abreast of the entire scope of this fast-changing field, from epidemiology to diagnosis to treatment to advocacy. Written in a straightforward, practical style for the busy clinician, this comprehensive, multidisciplinary title is a must-have for anyone involved in the care of patients with lung cancer and other thoracic malignancies. - Offers practical, relevant coverage of basic science, epidemiology, pulmonology, medical and radiation oncology, surgery, pathology, palliative care, nursing, and advocacy. - Provides authoritative guidance from the IASLC – the only global organization dedicated to the study of lung cancer. - Includes new content on molecular testing, immunotherapy, early detection, staging and the IASLC staging system, surgical resection for stage I and stage II lung cancer, and stem cells in lung cancer. - Features a new full-color design throughout, as well as updated diagnostic algorithms. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

Yen & Jaffe's Reproductive Endocrinology - E-Book

Yen & Jaffe's Reproductive Endocrinology - E-Book
Author: Jerome F. Strauss
Publisher: Elsevier Health Sciences
Total Pages: 1393
Release: 2023-03-24
Genre: Medical
ISBN: 032381008X

For over 40 years, Yen & Jaffe's Reproductive Endocrinology has been the gold standard text of both basic science and clinical practice of the full range of female and male reproductive disorders. The fully revised 9th Edition continues this tradition of excellence with complete coverage, including up-to-date information on impaired fertility, infertility, recurrent pregnancy loss, problems of sexual development, menstrual disturbances, fibroids, endometriosis, female and male reproductive aging, fertility preservation, assisted reproduction technologies including ovarian stimulation and ovulation induction, transgender hormonal treatment, contraception, and more. An outstanding editorial board and other global experts in the field share their knowledge and expertise to keep you abreast of current science and practice in endocrinology. - Includes new chapters on Meiosis, Fertilization and Embryo Development; Recurrent Pregnancy Loss; Uterus Transplantation; Mitochondrial Transplantation and Gene Editing; and Germs Cells Developed In Vitro. - Provides extensively revised information on contemporary practices in assisted reproduction, fertility preservation, and ovulation induction. - Provides an online video library that highlights surgical procedures, diagnostic imaging, and functional ultrasound imaging. - Adds three new members to the exceptional editorial team: Drs. Anuja Dokras, Carmen J. Williams, and Zev Williams. - Features full-color, high-quality illustrations that clearly depict basic anatomic structures, endocrine processes, and cell function and dysfunction. - Includes bulleted lists under major headings in each chapter for quick, at-a-glance summaries of every section. - Lists Top References at the end of each chapter that distill the most important references for research underpinnings, to complement the complete online reference list. - An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

The Gene Ontology Handbook

The Gene Ontology Handbook
Author: Christophe Dessimoz
Publisher:
Total Pages: 298
Release: 2020-10-08
Genre: Science
ISBN: 9781013267710

This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.