The Alpha Strain
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| Author | : Daniele Focosi |
| Publisher | : Springer Nature |
| Total Pages | : 140 |
| Release | : 2021-10-11 |
| Genre | : Medical |
| ISBN | : 3030873242 |
This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 376 |
| Release | : 2004-04-26 |
| Genre | : Medical |
| ISBN | : 0309182158 |
The emergence of severe acute respiratory syndrome (SARS) in late 2002 and 2003 challenged the global public health community to confront a novel epidemic that spread rapidly from its origins in southern China until it had reached more than 25 other countries within a matter of months. In addition to the number of patients infected with the SARS virus, the disease had profound economic and political repercussions in many of the affected regions. Recent reports of isolated new SARS cases and a fear that the disease could reemerge and spread have put public health officials on high alert for any indications of possible new outbreaks. This report examines the response to SARS by public health systems in individual countries, the biology of the SARS coronavirus and related coronaviruses in animals, the economic and political fallout of the SARS epidemic, quarantine law and other public health measures that apply to combating infectious diseases, and the role of international organizations and scientific cooperation in halting the spread of SARS. The report provides an illuminating survey of findings from the epidemic, along with an assessment of what might be needed in order to contain any future outbreaks of SARS or other emerging infections.
| Author | : WW Mortensen |
| Publisher | : WW Mortensen |
| Total Pages | : 444 |
| Release | : 2021-04-27 |
| Genre | : Fiction |
| ISBN | : 0648126447 |
The electrifying sequel to the WW Mortensen bestseller, EIGHT. 2,000 years ago, something mysterious stalked the jungles of the Congo. In Antarctica, a stunning discovery is made in 2,000-year-old ice. Deep in the Amazon, two months have passed since the incident that nearly cost entomologist Rebecca Riley her life. Separated from her companions and still dealing with the fallout, she struggles to heal and to forget, finding solace in her work. But when her research is seized, including evidence of the greatest discovery her field has ever seen, she is lured to the States and a top-secret military facility somewhere in Nevada. There, she uncovers a horrifying truth. They’ve brought something back. Something she hasn’t seen before. Something terrifying. A new species… a strange, new energy source… and a secret that will change human history. A secret others will kill for. When the facility goes offline, overrun by a force of mercenaries hell-bent on sabotaging the project, Rebecca again finds herself in a desperate fight for survival… and a race to save the future. She’ll need help from old friends, because the jungle had been hiding something… and now it’s coming for them all. TERROR HAS ADAPTED. AND ALL HELL IS ABOUT TO BREAK LOOSE.
| Author | : Mavis Agbandje-McKenna |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 389 |
| Release | : 2010-11-11 |
| Genre | : Medical |
| ISBN | : 184973223X |
Over the last ten years, much effort has been devoted to improving the biophysical techniques used in the study of viruses. This has resulted in the visualization of these large macromolecular assemblages at atomic level, thus providing the platform for functional interpretation and therapeutic design. Structural Virology covers a wide range of topics and is split into three sections. The first discusses the vast biophysical methodologies used in structural virology, including sample production and purification, confocal microscopy, mass spectrometry, negative-stain and cryo-electron microscopy, X-ray crystallography and nuclear magnetic resonance spectroscopy. The second discusses the role of virus capsid protein structures in determining the functional roles required for receptor recognition, cellular entry, capsid assembly, genome packaging and mechanisms of host immune system evasion. The last section discusses therapeutic strategies based on virus protein structures, including the design of antiviral drugs and the development of viral capsids as vehicles for foreign gene delivery. Each topic covered will begin with a review of the current literature followed by a more detailed discussion of experimental procedures, a step in the viral life cycle, or strategies for therapeutic development. With contributions from experts in the field of structural biology and virology this exceptional monograph will appeal to biomedical scientists involved in basic and /or applied research on viruses. It also provides up-to-date reference material for students entering the field of structural virology as well as scientists already familiar with the area.
| Author | : Michael Robertson |
| Publisher | : Michael Robertson |
| Total Pages | : 213 |
| Release | : 2023-05-06 |
| Genre | : Fiction |
| ISBN | : |
Do you have a plan for the apocalypse? Rhys doesn't. But as he watches chaos spill from the Alpha tower, he knows one thing for sure ... He must get to his son before the virus does. If you like high stakes and edge of your seat action in a post-apocalyptic world, then The Alpha Plague is for you. Get it now to join Rhys at ground zero as he tries to save his loved ones and survive a disaster that will leave the world changed forever.
| Author | : Sam Crescent |
| Publisher | : |
| Total Pages | : 270 |
| Release | : 2018-02-05 |
| Genre | : |
| ISBN | : 9781773395371 |
THE ALPHA'S TOY To spare an innocent she has to become his plaything. When Zeke attacks her pack, Mary, a half-breed wolf, wants to save a young wolf, but to do so, she has to accept his bargain. She must be his toy until the next full moon. Mary despises the alpha she must now give her body to, but she can't deny the response he inspires within her. Exploring the deceased pack's lair Zeke stumbles onto something that could destroy all breeds of wolf. The leaders of Mary's pack had been experimenting on wolves. The reasons why are still unknown, but Zeke will do everything in his power to find out the truth, especially when he discovers Mary was one of their experiments. Even before the end of the month Mary becomes all he can think about, and he's determined to keep his toy safe. Then a twist of fate lets him know she's more than a toy. Mary is his mate. Can he overcome her fear of him and convince her to stay when her month is up? ALPHA BAIT There is a law that binds an Alpha to his wolf and stops him from hurting others of his pack. If an Alpha lashes out with the intention to harm, then his wolf will stop it, forcing on the transition...but one wolf has found the loophole. Chain is determined to inflict harm. He sends out the one woman he wants but cannot have, Victoria. She will be his Alpha Bait, luring another Alpha to his death, thus freeing Chain from the control of his wolf. For most of her adult life Victoria has been at the mercy of Chain. He scares her more than anything else. Doing as she's told, Victoria sets the trap in order to gain Scorch's attention. Scorch is a good leader and strong Alpha. He will not hurt anyone. When a beautiful red-head ends up in his care, he cannot turn away from the attraction she inspires. Their wolves are mates, and they're destined to be together. However, what will Scorch do when he realizes Victoria is with him to lure him to his death? Can she really send the man she loves to his grave? Being Alpha Bait was never her choice, but who really holds her loyalty, Chain or Scorch?
| Author | : New York (N.Y.). Dept. of Health. Bureau of Laboratories |
| Publisher | : |
| Total Pages | : 600 |
| Release | : 1926 |
| Genre | : |
| ISBN | : |
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 431 |
| Release | : 2005-04-09 |
| Genre | : Medical |
| ISBN | : 0309095042 |
Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns. The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.
| Author | : |
| Publisher | : |
| Total Pages | : 728 |
| Release | : 1922 |
| Genre | : Communicable diseases |
| ISBN | : |
| Author | : |
| Publisher | : |
| Total Pages | : 120 |
| Release | : 1949 |
| Genre | : Agriculture |
| ISBN | : |
Set includes revised editions of some issues.
