Systems Biology and In-Depth Applications for Unlocking Diseases

Systems Biology and In-Depth Applications for Unlocking Diseases
Author: Babak Sokouti
Publisher: Elsevier
Total Pages: 356
Release: 2024-11-20
Genre: Science
ISBN: 0443223270

Systems Biology and In-Depth Applications for Unlocking Diseases: Principles, tools and Application to Disease provides the essence of systems biology approaches in a practical manner, illustrating the basic principles essential to develop and model in real life science applications. Methodologies covered show how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment. Sections provide an introduction and history of systems biology, discuss the tools and resources needed for structure and function of biological systems, and present evidence of systems biology in action. Examples include big data techniques, scale networks, mathematical model development, and much more. This is the perfect reference to provide the fundamental base of knowledge needed for systems biologists, professionals in systems medicine, computational biologists, and bioinformaticians. - Provides detailed and comprehensive coverage of the field of systems biology - Delivers instruction on how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment - Makes effective steps towards personalized medicine in the treatment of disease - Explains effective disease treatment strategies at early diagnosis stages

Systems Biology and In-Depth Applications for Unlocking Diseases

Systems Biology and In-Depth Applications for Unlocking Diseases
Author: Babak Sokouti
Publisher: Academic Press
Total Pages: 0
Release: 2025-02-01
Genre: Science
ISBN: 9780443223266

Systems Biology and In-Depth Applications for Unlocking Diseases: Principles, tools and Application to Disease provides the essence of systems biology approaches in a practical manner illustrating the basic principles essential to develop and model in real life science applications. Methodologies covered show how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment. Systematically written in 3 parts this book first provides an introduction and history of systems biology; next it provides the tools and resources needed for structure and function of biological systems; and finally, it provides the evidence of systems biology in action to better understand disease connections. Examples include big data techniques, scale networks, mathematical model development, and much more. This is the perfect reference to provide the fundamental base of knowledge needed for systems biologists, professionals in systems medicine, computational biologists, and bioinformaticians whether needed for immediate application or for building a comprehensive understanding of the field.

Bioinformatics: Applications of Computational Biology in Life Sciences

Bioinformatics: Applications of Computational Biology in Life Sciences
Author: Michael Roberts
Publisher: Richards Education
Total Pages: 159
Release:
Genre: Computers
ISBN:

Embark on a journey into the fascinating realm of bioinformatics with 'Bioinformatics: Exploring Computational Biology in Life Sciences.' This comprehensive book delves into the applications of computational techniques in understanding biological systems, from sequence analysis and genome assembly to structural biology and systems biology. Whether you're a researcher, student, or industry professional, each chapter provides in-depth insights, methodologies, and real-world examples that highlight the transformative impact of bioinformatics on modern life sciences. Navigate the complexities of biological data analysis and discover how computational biology is shaping the future of healthcare, agriculture, and beyond.

New Frontiers and Applications of Synthetic Biology

New Frontiers and Applications of Synthetic Biology
Author: Vijai Singh
Publisher: Academic Press
Total Pages: 487
Release: 2022-01-12
Genre: Science
ISBN: 0323859860

New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more. This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas. - Offers basic understanding and knowledge in several aspects of synthetic biology - Covers state-of-the-art tools and technologies of synthetic biology, including promoter design, DNA synthesis, DNA sequencing, genome design, directed evolution, protein engineering, computational tools, phage design, CRISPR-Cas systems, and more - Discusses the applications of synthetic biology for smart drugs, vaccines, therapeutics, drug discovery, self-assembled materials, cell free systems, microfluidics, and more

Applications of Synthetic Biology in Health, Energy, and Environment

Applications of Synthetic Biology in Health, Energy, and Environment
Author: Arshad, Muhammad
Publisher: IGI Global
Total Pages: 481
Release: 2023-10-02
Genre: Science
ISBN: 1668465787

The application of genetic engineering techniques by redesigning and repurposing biological systems for novel biotechnical applications has paved the way for the field of synthetic biology. This field boosted the evolution and discovery of various novel technologies essential to the conquest of biological problems related to health, disease, the environment, and energy. The field of synthetic biology is growing rapidly, and further research is required. Applications of Synthetic Biology in Health, Energy, and Environment deliberates on principles and the advancement of synthetic biology and their translation in the fields of health, disease, energy, and the environment. Covering topics such as climate change, bioremediation, and smart drugs, this premier reference source is an excellent resource for students and educators of higher education, industrialists, medical professionals, hospital administrators, policymakers, environmental scientists, pharmacists, librarians, researchers, and academicians.

Synthetic Biology

Synthetic Biology
Author: Shailza Singh
Publisher: Springer
Total Pages: 261
Release: 2018-10-01
Genre: Medical
ISBN: 9811086931

The book uses an integrated approach to predict the behavior of various biological interactions. It further discusses how synthetic biology gathers the information about various systems, in order to either devise an entirely new system, or, to modulate existing systems. The book also tackles the concept of modularity, where biological systems are visualized in terms of their parts. The chapters discuss how the principles of engineering are being used in biomedical sciences, to design biological circuits that can harbor multiple inputs and generate multiple outputs; to create genetic networks and control gene activity, in order to generate a desired response. The book aims to help the readers develop an array of biological parts, and to use these parts to develop synthetic circuits that can be assembled like electronic circuits. The ultimate aim of the book will be to serve as an amalgamation of key ideas of how judiciously synthetic biology could be exploited in therapeutic device and delivery mechanism.

Diagnostics and Gene Therapy for Human Genetic Disorders

Diagnostics and Gene Therapy for Human Genetic Disorders
Author: K.V. Chaitanya
Publisher: CRC Press
Total Pages: 461
Release: 2022-12-30
Genre: Science
ISBN: 1000824527

Diagnostics and Gene Therapy for Human Genetic Disorders provides an integrative and comprehensive source of information blending classical human genetics with the human genome. It provides a multidisciplinary overview of Mendelian inheritance and multifactorial inheritance, genetic variations, polymorphisms, chromosomal, multifactorial, and mitochondrial disorders. PCR, electrophoresis, cytogenetics, prenatal, and HPLC based techniques applied for diagnosing genetic disorders are discussed with applications. Symptoms, etiology, diagnosis, treatment of 14 major and 5 minor genetic disorders are discussed in detail. Methods employed for the preparation of kits for the diagnosis of diseases are provided. The role of gene therapy in the amelioration of genetic disorders and the methodology employed are discussed. The success of gene therapy in controlling various disorders such as immune system disorders, neurodegenerative disorders, cardiovascular disorders, eye diseases, and cancer has been described along with type studies. Features: A blend of classical human genetics with molecular and genome-based applications Techniques applied for the diagnosis of genetic disorders Diagnostics of 19 genetic disorders including symptoms, etiology, diagnosis, and treatment Role of gene therapy in the amelioration of disorders Type studies describing the role of diagnostics in conserving the human health This book attempts to connect all the information about classical and modern human genetics, genetic disorders, and gene therapy to all types of diseases in one place. This work provides a comprehensive source of information that can serve as a reference book for scientific investigations and as a textbook for the graduate students.