Synthetic Methods Of Organic Chemistry
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| Author | : Stéphane Caron |
| Publisher | : John Wiley & Sons |
| Total Pages | : 850 |
| Release | : 2020-02-05 |
| Genre | : Science |
| ISBN | : 1119448859 |
This book is a hands-on guide for the organic chemist. Focusing on the most reliable and useful reactions, the chapter authors provide the information necessary for a chemist to strategically plan a synthesis, as well as repeat the procedures in the laboratory. Consolidates all the key advances/concepts in one book, covering the most important reactions in organic chemistry, including substitutions, additions, eliminations, rearrangements, oxidations, reductions Highlights the most important reactions, addressing basic principles, advantages/disadvantages of the methodology, mechanism, and techniques for achieving laboratory success Features new content on recent advances in CH activation, photoredox and electrochemistry, continuous chemistry, and application of biocatalysis in synthesis Revamps chapters to include new and additional examples of chemistry that have been demonstrated at a practical scale
| Author | : Stéphane Caron |
| Publisher | : John Wiley & Sons |
| Total Pages | : 870 |
| Release | : 2011-07-26 |
| Genre | : Science |
| ISBN | : 1118093569 |
A hands-on guide to assist in the planning and execution of synthetic reactions in the laboratory Despite the maturity of organic chemistry, it can still be very challenging to identify optimal methods for synthetic transformations that perform as well in real-world manufacturing processes as they do in the laboratory. This detailed and accessible guide attempts to address this vexing issue and deliver proven methodologies practicing synthetic chemists will find valuable for identifying reaction conditions that work reliably over the broadest possible range of substrates. Practical Synthetic Organic Chemistry: Provides a practical guide to strategically planning and executing chemical syntheses for the bench chemist in industry Discusses information that is not common knowledge beyond the boundaries of process chemistry groups, such as the synthetic routes of selected contemporary pharmaceutical drugs and practical solvents, as well as green chemistry concepts Highlights key reactions, including substitutions, additions, eliminations, rearrangements, oxidations, and reductions Addresses basic principles, mechanisms, advantages and disadvantages of the methodology, and techniques for achieving laboratory success Incorporating such an extraordinary wealth of information on organic chemistry and its related fields into one complete volume distinguishes Practical Synthetic Organic Chemistry as an incomparable desktop reference for professionals and an invaluable study aid for students.
| Author | : W. Carruthers |
| Publisher | : Cambridge University Press |
| Total Pages | : 416 |
| Release | : 1971-10-31 |
| Genre | : Science |
| ISBN | : 9780521081450 |
| Author | : James Ralph Hanson |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 188 |
| Release | : 2002 |
| Genre | : Education |
| ISBN | : 9780854046829 |
This book introduces the major methods of creating carbon-carbon and carbon-nitrogen bonds, along with functional group interconversions.
| Author | : Paul Wyatt |
| Publisher | : John Wiley & Sons |
| Total Pages | : 55 |
| Release | : 2013-05-20 |
| Genre | : Science |
| ISBN | : 1118681444 |
Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren's bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. * A comprehensive, practical account of the key concepts involved in synthesising compounds * Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations * Focuses on reactions that really work rather than those with limited application * Contains extensive, up-to-date references in each chapter Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.
| Author | : Laurie S. Starkey |
| Publisher | : John Wiley & Sons |
| Total Pages | : 360 |
| Release | : 2012-01-18 |
| Genre | : Science |
| ISBN | : 1118180852 |
The stepping-stone text for students with a preliminary knowledge of organic chemistry looking to move into organic synthesis research and graduate-level coursework Organic synthesis is an advanced but important field of organic chemistry, however resources for advanced undergraduates and graduate students moving from introductory organic chemistry courses to organic synthesis research are scarce. Introduction to Strategies for Organic Synthesis is designed to fill this void, teaching practical skills for making logical retrosynthetic disconnections, while reviewing basic organic transformations, reactions, and reactivities. Divided into seven parts that include sections on Retrosynthesis and Protective Groups; Overview of Organic Transformations; Synthesis of Monofunctional Target Molecules; Synthesis of Target Molecules with Two Functional Groups; Synthesis of Aromatic Target Molecules; Synthesis of Compounds Containing Rings; and Predicting and Controlling Stereochemistry, the book covers everything students need to successfully perform retrosynthetic analyses of target molecule synthesis. Starting with a review of functional group transformations, reagents, and reaction mechanisms, the book demonstrates how to plan a synthesis, explaining functional group analysis and strategic disconnections. Incorporating a review of the organic reactions covered, it also demonstrates each reaction from a synthetic chemist's point of view, to provide students with a clearer understanding of how retrosynthetic disconnections are made. Including detailed solutions to over 300 problems, worked-through examples and end-of-chapter comprehension problems, Introduction to Strategies for Organic Synthesis serves as a stepping stone for students with an introductory knowledge of organic chemistry looking to progress to more advanced synthetic concepts and methodologies.
| Author | : David John Ager |
| Publisher | : CRC Press |
| Total Pages | : 506 |
| Release | : 1995-11-21 |
| Genre | : Science |
| ISBN | : 9780849389429 |
This comprehensive text presents a critical discussion of the scopes and limitations of various organic synthetic methodologies that are available for performing asymmetric transformations. In addition to purely chemical methods, the book covers applications of new enzymes and other biological systems that are increasingly useful in asymmetric methodology.
| Author | : Basil J. Wakefield |
| Publisher | : Academic Press |
| Total Pages | : 269 |
| Release | : 1995-03-16 |
| Genre | : Science |
| ISBN | : 0080538177 |
The book opens with a general overview of the constitution and reactivity of organomagnesium compounds, followed by information on handling them and on their detection and estimation. Throughout, practical aspects aswell as principles are emphasized. The chapters on the synthesis of organomagnesium compounds cover the preparation of special forms of metallic magnesium and the reaction of magnesium with substrates such as dienes, as well as the traditional preparation of Grignard reagents. Preparations by metallation and metal-halogen exchanges are also included, as are newer methods such as hydromagnesiation of alkenes and alkynes. Systematic coverage is provided on synthetically useful reactions of organomagnesium compounds. Of fundamental importance in organic synthesis are carbon-carbon bond forming reactions; additions to carbon-carbon, carbon-nitrogen, carbon-oxygen, and carbon-sulfur multiple bonds; and nucleophilic substitution at carbon. The formation of carbon-heteroatom bonds in organic compounds is described, where the heteroatom is hydrogen, nitrogen, oxygen, sulfur, or halogen. Finally, the use of organomagnesium compounds in preparing other organometalloid and organometallic compounds is outlined. Representative experimental procedures are included throughout the book, and tables with references to well-described examples are provided. - Presents a general overview of the constitution and reactivity of organomagnesium compounds - Provides coverage on the detection and estimation of organomagnesium compounds - Emphasizes practical aspects as well as principles - Covers the preparation of special forms of metallic magnesium and the reaction of magnesium with substrates such as dienes - Includes preparations by metallation and metal-halogen exchanges - Reviews new preparation methods such as hydromagnesiation of alkenes and alkynes - Outlines information on synthetically useful reactions of organomagnesium compounds - Describes the formation of carbon-heteroatom bonds in organic compounds - Addresses the use of organomagnesium compounds in preparing other organometalloid and organometallic compounds - Includes representative procedures and tables with references to well-described examples
| Author | : Raj K. Bansal |
| Publisher | : Jones & Bartlett Learning |
| Total Pages | : 436 |
| Release | : 1996 |
| Genre | : Science |
| ISBN | : 9780763706654 |
Designed for undergraduate and beginning graduate courses in organic synthesis.
| Author | : W. Carruthers |
| Publisher | : Cambridge University Press |
| Total Pages | : 506 |
| Release | : 2015-04-10 |
| Genre | : Political Science |
| ISBN | : 1107567459 |
Textbook on modern methods of organic synthesis.
