Studies Of Ubiquinone Synthesis In E Coli
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Microbial Respiration
Author | : Walter P. Hempfling |
Publisher | : Hutchinson Ross Publishing Company |
Total Pages | : 360 |
Release | : 1979 |
Genre | : Medical |
ISBN | : |
Industrial Biotechnology
Author | : Christoph Wittmann |
Publisher | : John Wiley & Sons |
Total Pages | : 789 |
Release | : 2017-04-10 |
Genre | : Science |
ISBN | : 352734179X |
The latest volume in the Advanced Biotechnology series provides an overview of the main production hosts and platform organisms used today as well as promising future cell factories in a two volume book. Alongside describing tools for genetic and metabolic engineering for strain improvement, the authors also impart topical information on computational tools, safety aspects and industrial-scale production. Following an introduction to general concepts, historical developments and future technologies, the text goes on to cover multi-purpose bacterial cell factories, including those organisms that exploit anaerobic biosynthetic power. Further chapters deal with microbes used for the production of high-value natural compounds and those obtained from alternative raw material sources, concluding with eukaryotic workhorses.
Coenzyme Q in Aging
Author | : Guillermo López Lluch |
Publisher | : Springer |
Total Pages | : 0 |
Release | : 2020-08-07 |
Genre | : Medical |
ISBN | : 9783030456412 |
This book offers a comprehensive exploration of research on the essential relationship of the coenzyme Q10 and the process of aging in living organisms. CoQ10 is an important factor in two main aspects of cell physiology: bioenergetics and antioxidant protection. While primary deficiency of CoQ10 is associated with severe and lethal disease, secondary deficiency can be associated with the progression of mitochondrial dysfunction linked to the lessening of biological activities during aging. The book is organized in four sections. The first offers an overview of the function of CoQ10, highlighting the two main functions of CoQ10 in cells: its essential role as electron transport chain member in mitochondria, and the protection of cell membranes against oxidation as one of the main endogenous-synthesized antioxidants. The second section covers research on Coenzyme 10. Topics include studies involving invertebrate models, mammal studies and the influence of CoQ on longevity. Also covered is research involving the role of CoQ in senescence-accelerated mice. Section three examines the effects of reduced CoQ in human aging, as evident in mitochondrial dysfunction, metabolic syndrome, neurodegenerative disorders, immunosenescence and fertility and reproduction. The final section, Prolongevity effectors and Coenzyme Q, explores research into slowing or stopping the aging process. Coverage includes strategies including calorie restriction, and modulation of CoQ10 levels by induction of synthesis or by supplementation. Coenzyme Q in Aging benefits a broad readership of researchers, clinicians, educators and students interested in the biochemical and physiological effects of coenzyme Q and the importance of this molecule in aging process.
Coenzyme Q
Author | : Giorgio Lenaz |
Publisher | : John Wiley & Sons |
Total Pages | : 536 |
Release | : 1985 |
Genre | : Medical |
ISBN | : |
It is becoming increasingly apparent that Coenzyme Q (Ubiquinone) is a major component of the electron transfer chains within aerobic micro-oganisms, photo-synthetic micro-organisms and mitochondria of eukaryotes. In particular, the proposal by Nobel laureate, Peter Mitchell, that Coenzyme Q possibly acts as a proton translocator within a proton motive Q-cycle, thus establishing an electrochemical membrane potential which in turn drives ATP synthesis, has received wide attention. This exhaustive, inter-disciplinary study discusses Ubiquinone's chemical and physical properties, metabolism, and function in different organisms.
The Shikimate Pathway
Author | : Edwin Haslam |
Publisher | : Elsevier |
Total Pages | : 327 |
Release | : 2014-05-20 |
Genre | : Science |
ISBN | : 1483161188 |
The Shikimate Pathway gives a bird's eye view of the shikimate pathway and its implications for the life of a range of organisms. Topics covered in this book include the chemistry of intermediates in the shikimate pathway; biosynthesis of aromatic amino acids in this pathway; its metabolites; and its role in higher plants. This book is comprised of six chapters and begins by introducing the reader to shikimic acid, a natural product derived from the plant Illicium religiosum, along with the mechanistic and stereochemical aspects of the reactions of the shikimate pathway. The biosynthesis of aromatic amino acids from chorismate is also described, and then the discussion turns to the chemical properties and the detailed stereochemistry of intermediates and enzymes in the shikimate pathway. The next chapter examines the biosynthesis of isoprenoid quinones involved in electron transport and the folic acid group of co-enzymes in the shikimate pathway. The metabolism of the aromatic amino acids in microorganisms and higher organisms is considered, along with the biosynthesis and physiological functions of phenylpropanoid compounds and their derivatives in the shikimate pathway in higher plants. This book will be of general value to practitioners in the many and varied areas of biochemical research associated with metabolism.
Biogenesis of Fatty Acids, Lipids and Membranes
Author | : Otto Geiger |
Publisher | : Springer |
Total Pages | : 0 |
Release | : 2019-01-29 |
Genre | : Science |
ISBN | : 9783319504292 |
Concise chapters, written by experts in the field, cover a wide spectrum of topics on lipid and membrane formation in microbes (Archaea, Bacteria, eukaryotic microbes).All cells are delimited by a lipid membrane, which provides a crucial boundary in any known form of life. Readers will discover significant chapters on microbial lipid-carrying biomolecules and lipid/membrane-associated structures and processes.
Cyanobacteria Biotechnology
Author | : Paul Hudson |
Publisher | : John Wiley & Sons |
Total Pages | : 560 |
Release | : 2021-04-20 |
Genre | : Science |
ISBN | : 352782491X |
Unites a biological and a biotechnological perspective on cyanobacteria, and includes the industrial aspects and applications of cyanobacteria Cyanobacteria Biotechnology offers a guide to the interesting and useful features of cyanobacteria metabolism that keeps true to a biotechnology vision. In one volume the book brings together both biology and biotechnology to illuminate the core acpects and principles of cyanobacteria metabolism. Designed to offer a practical approach to the metabolic engineering of cyanobacteria, the book contains relevant examples of how this metabolic "module" is currently being engineered and how it could be engineered in the future. The author includes information on the requirements and real-world experiences of the industrial applications of cyanobacteria. This important book: Brings together biology and biotechnology in order to gain insight into the industrial relevant topic of cyanobacteria Introduces the key aspects of the metabolism of cyanobacteria Presents a grounded, practical approach to the metabolic engineering of cyanobacteria Offers an analysis of the requirements and experiences for industrial cyanobacteria Provides a framework for readers to design their own processes Written for biotechnologists, microbiologists, biologists, biochemists, Cyanobacteria Biotechnology provides a systematic and clear volume that brings together the biological and biotechnological perspective on cyanobacteria.
Synthetic Biology of Cyanobacteria
Author | : Weiwen Zhang |
Publisher | : Springer |
Total Pages | : 357 |
Release | : 2018-08-08 |
Genre | : Medical |
ISBN | : 9811308543 |
This volume highlights recent breakthroughs in the interdisciplinary areas of synthetic biology, metabolic engineering and bioprocess engineering for the production of green chemicals. It also presents practical experimental and computational tools for the design, construction and manipulation of cyanobacteria cell factories. The respective contributions cover new technologies in the field, such as novel genetic transformation techniques and bioinformatics analysis methods and address various aspects of cyanobacterial synthetic biology, offering a valuable resource for students and researchers in the fields of industry microbiology and biomedical engineering.
Nutrient Metabolism
Author | : Martin Kohlmeier |
Publisher | : Elsevier |
Total Pages | : 841 |
Release | : 2003-10-01 |
Genre | : Medical |
ISBN | : 0080537898 |
Nutrient Metabolism defines the molecular fate of nutrients and other dietary compounds in humans, as well as outlining the molecular basis of processes supporting nutrition, such as chemical sensing and appetite control. It focuses on the presentation of nutritional biochemistry; and the reader is given a clear and specific perspective on the events that control utilization of dietary compounds. Slightly over 100 self-contained chapters cover all essential and important nutrients as well as many other dietary compounds with relevance for human health. An essential read for healthcare professionals and researchers in all areas of health and nutrition who want to access the wealth of nutrition knowledge available today in one single source.Key Features* Highly illustrated with relevant chemical structures and metabolic pathways* Foreword by Steven Zeisel, Editor-in-chief of the Journal of Nutritional Biochemistry* First comprehensive work on the subject