Structural And Resonance Techniques In Biological Research
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| Author | : Denis Rousseau |
| Publisher | : Elsevier |
| Total Pages | : 491 |
| Release | : 2012-12-02 |
| Genre | : Science |
| ISBN | : 0323148301 |
Structural and Resonance Techniques in Biological Research discusses the fundamentals and applications of nuclear magnetic resonance, electron spin resonance, Mössbauer spectroscopy, x-ray absorption spectroscopy, macromolecular crystallography, and small-angle x-ray scattering and diffraction. The chapters are aimed at a level such that only a general understanding of chemistry and biology is required. The objective is to present material in a way that allows the research worker to assess quickly the applicability, utility, and significance of the specific technique to his or her problem or field of interest. Together with Optical Techniques in Biological Research, this book marks the introduction of a new series of volumes, Physical Techniques in Biology and Medicine, which is intended to replace a previous treatise, Physical Techniques in Biological Research.
| Author | : John L. Markley |
| Publisher | : Oxford University Press |
| Total Pages | : 375 |
| Release | : 1997-01-30 |
| Genre | : Medical |
| ISBN | : 0195094689 |
This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.
| Author | : Toshiya Senda |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2016-08-03 |
| Genre | : Science |
| ISBN | : 9784431560289 |
This book provides practical information on a whole set of protein experiments for advanced structural biology, such as X-ray crystallography, NMR, electron microscopy, advanced mass spectroscopy, and surface plasmon resonance, as well as a wide variety of expression systems including eukaryotic and in vitro expression. In the past decade, structural genomics studies have pushed forward the development of automated methods in the field of structural biology, however there is an increasing need for the structural analysis of difficult targets, such as large protein complexes and membrane proteins, which are hard to achieve using conventional automated methods, and require knowledge that goes beyond standard protein chemistry protocols. To address these problems and to help researchers develop novel methods, this volume provides examples of the development of new protein investigation methods and their theoretical background. This book particularly appeals to graduate students, postdoctoral researchers, young investigators wishing to gain a better understanding of the theory behind experiments, and those seeking further advanced, practical structural biology methods.
| Author | : National Library of Medicine (U.S.) |
| Publisher | : |
| Total Pages | : 782 |
| Release | : |
| Genre | : Medicine |
| ISBN | : |
First multi-year cumulation covers six years: 1965-70.
| Author | : A. Ehrenberg |
| Publisher | : Elsevier |
| Total Pages | : 441 |
| Release | : 2013-09-24 |
| Genre | : Science |
| ISBN | : 148322676X |
Magnetic Resonance in Biological Systems, Volume 9 is a collection of manuscripts presented at the Second International Conference on Magnetic Resonance in Biological Systems, held in Wenner-Gren Center, Stockholm, Sweden on June 1966. The conference is sponsored by International Union of Biochemistry Swedish Medical Research Council Swedish Natural Science Research Council Wenner-Gren Center Foundation for Scientific Research. This book contains 51 chapters, and begins with reviews of NMR investigations of biological macromolecules, including proteins, amino acids, and glycylglycine copper (II). Considerable chapters are devoted to numerous biological studies using the electronic paramagnetic resonance (EPR), thus introducing the branch of science called submolecular biology. This book also explores other applications of NMR and EPR, with special emphasis on blood component analysis and protein-metal complexes. The final chapters survey the principles and applications of Mössbauer spectroscopy. This book will prove useful to analytical chemists and biologists.
| Author | : Subrata Pal |
| Publisher | : Academic Press |
| Total Pages | : 518 |
| Release | : 2019-08-15 |
| Genre | : Science |
| ISBN | : 0128148551 |
Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a "fundamentals" book to get them up-to-speed on the foundations of a particular field. This book fills that niche.
| Author | : Matt Carter |
| Publisher | : Academic Press |
| Total Pages | : 416 |
| Release | : 2022-03-26 |
| Genre | : Medical |
| ISBN | : 0323915612 |
Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step
| Author | : Franz Muller |
| Publisher | : CRC Press |
| Total Pages | : 685 |
| Release | : 2019-07-22 |
| Genre | : Medical |
| ISBN | : 1351079018 |
Chemistry and Biochemistry of Flavoenzymes summarizes the present knowledge of the chemical and physical properties of free flavin, modified flavins occurring in nature, and deazaflavin. This information forms the fundamental basis for understanding the catalytic properties of flavoenzymes. Flavoproteins involved in transport, electron transfer, oxidation, dehydrogenation and hydroxylation reactions are discussed with respect to their biochemical and biophysical properties. The book presents the catalytic mechanisms of the flavoproteins in detail and, where available, three-dimensional structures and molecular biology data are included. The medical aspects of free and protein-bound flavin are also briefly discussed. Chemistry and Biochemistry of Flavoenzymes is an essential reference source for chemists, biochemists, toxicologists, biologists, pharmacologists, and researchers in the pharmaceutical industry.
| Author | : Timir Tripathi |
| Publisher | : Academic Press |
| Total Pages | : 716 |
| Release | : 2022-01-14 |
| Genre | : Science |
| ISBN | : 0323902650 |
Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application. - Presents a thorough overview of the latest and emerging methods and technologies for protein study - Explores biophysical techniques, including nuclear magnetic resonance, X-ray crystallography, and cryo-electron microscopy - Includes computational and machine learning methods - Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins
| Author | : |
| Publisher | : |
| Total Pages | : 834 |
| Release | : 1987 |
| Genre | : Medicine |
| ISBN | : |
