Special Issue Alzheimers Disease Advances For A New Century
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Alzheimer’s Disease: Advances for a New Century
| Author | : IOS Press |
| Publisher | : IOS Press |
| Total Pages | : 486 |
| Release | : 2013-02-15 |
| Genre | : Medical |
| ISBN | : 1614991545 |
This volume is a companion to the highly successful book published in association with the Journal of Alzheimer’s Disease (JAD) on the centennial of Alzheimer’s discovery: “Alzheimer’s Disease: A Century of Scientific and Clinical Research”. Instead of looking back, this collection, “Alzheimer’s Disease: Advances for a New Century”, will look forward. Using scientometric analysis the most promising developments since the Alzheimer Centennial in 2006 have been substantiated. While prior trends and advances in genetics, amyloid-?, tau, neuropathology, and oxidative stress continue as active areas, emergent areas impacting the transition from normal cognition to Alzheimer’s disease such as diagnostic imaging, biomarkers, metabolism, and lifestyle (areas conceived only a few years ago) now dominate the debate. Invited contributors have summarized their landmark publications identified by our analysis and have put them into perspective, explaining the impetus behind the work, the contribution of the results to the field, and who played a role in the work.
Alzheimer's Disease
| Author | : George Perry |
| Publisher | : IOS Press |
| Total Pages | : 478 |
| Release | : 2006 |
| Genre | : Medical |
| ISBN | : 9781586036195 |
"This is the book edition of the Journal of Alzheimer's Disease, Volume 9, No.3 Supplement (2006)"--T.p. verso.
Alzheimer's Disease Drug Development
| Author | : Jeffrey Cummings |
| Publisher | : Cambridge University Press |
| Total Pages | : 575 |
| Release | : 2022-03-31 |
| Genre | : Business & Economics |
| ISBN | : 1108838669 |
Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
High-Octane Brain
| Author | : Michelle Braun |
| Publisher | : Union Square + ORM |
| Total Pages | : 200 |
| Release | : 2020-10-20 |
| Genre | : Self-Help |
| ISBN | : 1454937793 |
From a Harvard- and Yale-trained neuropsychologist, a science-backed five-step program to boost memory and dramatically decrease the risk of Alzheimer’s. American adults fear Alzheimer’s more than any other disease—including cancer—and because many don’t realize there is no genetic cause for 99 percent of Alzheimer’s cases, they don’t take the necessary steps to change lifestyle factors shown to significantly protect against the disease. In this book, board-certified neuropsychologist Dr. Michelle Braun inspires you to make lasting improvements by explaining the truth about brain health and providing expert guidance through the maze of conflicting media advice on supplements, brain games, nutrition, and exercise. Braun interviews eight leading brain health experts, combining their insights with cutting-edge research to offer proven strategies to implement the five steps of the High-Octane Brain. Interactive exercises help you develop a personalized program for optimal brain health. Dr. Braun also provides a tracking system with a visual depiction of progress, and shows the High-Octane Brain plan in action through the lives of clients. Packed with valuable tips you can implement immediately to minimize common “brain blips,” exercises to boost your memory within minutes, and inspiring insights from nine High-Octane Brain role models ages 44 to 103, this groundbreaking book helps put the future of your brain in your control. “Thorough, backed up by the best available research, and accessible.” —Barry Gordon, M.D., Ph.D., Director, Cognitive Neurology/Neuropsychology Division, Department of Neurology, Johns Hopkins Medical Institutions and University
The Problem of Alzheimer's
| Author | : Jason Karlawish |
| Publisher | : St. Martin's Press |
| Total Pages | : 269 |
| Release | : 2021-02-23 |
| Genre | : Health & Fitness |
| ISBN | : 1250218748 |
A definitive and compelling book on one of today's most prevalent illnesses. In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. 16 million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their seventies and eighties, the number of patients will rise to an estimated 13.8 million by 2050. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis. While it is an unambiguous account of decades of missed opportunities and our health care systems’ failures to take action, it tells the story of the biomedical breakthroughs that may allow Alzheimer’s to finally be prevented and treated by medicine and also presents an argument for how we can live with dementia: the ways patients can reclaim their autonomy and redefine their sense of self, how families can support their loved ones, and the innovative reforms we can make as a society that would give caregivers and patients better quality of life. Rich in science, history, and characters, The Problem of Alzheimer's takes us inside laboratories, patients' homes, caregivers’ support groups, progressive care communities, and Jason Karlawish's own practice at the Penn Memory Center.
The Neurobiology of Aging and Alzheimer Disease in Down Syndrome
| Author | : Elizabeth Head |
| Publisher | : Academic Press |
| Total Pages | : 354 |
| Release | : 2021-08-31 |
| Genre | : Medical |
| ISBN | : 0128188464 |
The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena. - Discusses the complexities involved with aging and Alzheimer's disease in Down syndrome - Summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age - Serves as learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research
The Alzheimer Conundrum
| Author | : Margaret Lock |
| Publisher | : Princeton University Press |
| Total Pages | : 328 |
| Release | : 2015-10-20 |
| Genre | : Social Science |
| ISBN | : 0691168474 |
Why our approaches to Alzheimer's and dementia are problematic and contradictory Due to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no effective treatment has been discovered for Alzheimer's disease, the most common form of dementia. The Alzheimer Conundrum exposes the predicaments embedded in current efforts to slow down or halt Alzheimer’s disease through early detection of pre-symptomatic biological changes in healthy individuals. Based on a meticulous account of the history of Alzheimer’s disease and extensive in-depth interviews, Margaret Lock highlights the limitations and the dissent associated with biomarker detection. Lock argues that basic research must continue, but should be complemented by a public health approach to prevention that is economically feasible, more humane, and much more effective globally than one exclusively focused on an increasingly harried search for a cure.
Neuroprotection in Alzheimer's Disease
| Author | : Illana Gozes |
| Publisher | : Academic Press |
| Total Pages | : 344 |
| Release | : 2016-12-30 |
| Genre | : Psychology |
| ISBN | : 0128037121 |
Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer’s disease will pave the path to better disease management and novel therapeutics. Comprehensive reference detailing neuroprotection in Alzheimer’s Disease, with details on nerve cell protection and new advances in disease management Combines the knowledge and points-of-view of both medical doctors and basic scientists, putting the subject at the forefront for further clinical development Edited by one of the leading researchers in Alzheimer’s Disease
