Volume 66 of Reviews in Mineralogy and Geochemistry is based on a two day short course entitled Paleoaltimetry: Geochemical and Thermodynamic Approaches held prior to the Geological Society of American annual meeting in Denver, Colorado (October 26-27, 2007). This meeting and volume were sponsored by the Geochemical Society, Mineralogical Society of America, and the United States Department of Energy. Contents: The Significance of Paleotopography Stable Isotope-Based Paleoaltimetry: Theory and Validation Paleoelevation Reconstruction Using Pedogenic Carbonates Stable Isotope Paleoaltimetry in Orogenic Belts – The Silicate Record in Surface and Crustal Geological Archives Paleoaltimetry from Stable Isotope Compositions of Fossils A Review of Paleotemperature–Lapse Rate Methods for Estimating Paleoelevation from Fossil Floras Paleoaltimetry: A Review of Thermodynamic Methods Paleoelevation Measurement on the Basis of Vesicular Basalts Stomatal Frequency Change Over Altitudinal Gradients: Prospects for Paleoaltimetry Thermochronologic Approaches to Paleotopography Terrestrial Cosmogenic Nuclides as Paleoaltimetric Proxies