Following the re-introduction of the African swine fever virus (ASFV) in the Americas after 40 years of absence, FAO conducted a qualitative risk assessment for the likelihood of entry of ASF from the Dominican Republic and Haiti to unaffected countries and territories of the Americas and the likelihood of exposure to susceptible animal populations should the disease be introduced. In addition, the potential economic and social impact of ASFV spreading across the continent was assessed. The risk assessment covers the period of December 2021 to February 2022 and considered six risk pathways of introduction and spread. The methodology, information used and results of the risk assessment and economic impact assessment are available in this publication along with recommendations for prevention and control of ASFV introduction and spread in the region. In addition, the publication compiles information collected from 35 countries/territories in the Americas through a questionnaire and presents evidence on the complex swine/pork value chains in the region retrieved from various sources.