Sildenafil
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| Author | : Udo Dunzendorfer |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 216 |
| Release | : 2004-10-25 |
| Genre | : Architecture |
| ISBN | : 9783764362553 |
This drug is a landmark discovery, which consequently has become the definitive therapy for the treatment of erectile dysfunction (ED). Following the major breakthrough in the field of nitric oxide (NO)-physiology and pharmacology leading to sildenafil being marketed, the most current information is presented in this reference book, including ongoing research from several disparate groups about NO as endothelium-derived relaxing factor (EDRF) and also as a neurotransmitter for nerves innervating erectile tissue in mammals. The development of sildenafil as an oral phosphodiesterase-5 (PDE5) inhibitor drug for the treatment of ED resulted in one of the first products, which made its way successfully from basic NO research to routine clinical therapy. This volume addresses all fields of sildenafil application in both men and women. In a highly competitive research environment with a critical medical need for drug improvements the reader will learn more about clinical resistance to sildenafil treatment and the modalities to overcome the failure rates. The individual chapters cover clinical use, pharmacokinetics, pharmacodynamics, biochemistry, and cultural aspects. They are written by leading experts in their respective fields. Therefore, readers a?? whether professionals in the pharmaceutical industry, physicians treating ED, biochemists, chemists or pharmacologists a?? will find a detailed and up-to-date knowledge base about current research activities and an excellent overview for further research on this compound class and its cultural impact.
| Author | : Udo Dunzendorfer |
| Publisher | : Birkhäuser |
| Total Pages | : 203 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3034879458 |
Sildenafil, for the treatment of erectile dysfunction, is one of the first products that has made its way successfully from basic NO (nitrous oxide) research, to clinical routine therapy. Sidenafil, part of the Milestones in Drug Therapy series, presents the major breakthroughs in the field of NO physiology and pharmacology that led to the development of the drug, as well as clinical applications in one source guide. Written by leading experts in the field, each chapter covers aspects of clinical use and experience, pharmacokinetics, pharmacodynamics, biochemistry, and cultural science.
| Author | : Larry Katzenstein |
| Publisher | : |
| Total Pages | : 132 |
| Release | : 2001 |
| Genre | : Health & Fitness |
| ISBN | : 9780966371314 |
| Author | : Ruben Vardanyan |
| Publisher | : Academic Press |
| Total Pages | : 870 |
| Release | : 2016-01-07 |
| Genre | : Medical |
| ISBN | : 0124115241 |
Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. - Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas - Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more - Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation
| Author | : Doctor Herry Blend |
| Publisher | : Lulu.com |
| Total Pages | : 47 |
| Release | : 2019-06-24 |
| Genre | : Science |
| ISBN | : 0359748716 |
Viagra medicine has been a wonderful and effective treatment for erectile dysfunction in over 95%%%% impotent men who are suffering of persistent poor sexual arousal, poor sexual desire or libido, quick ejaculation, weak erection, small size penile muscular tissue and consequently not able to sexually perform perfectly with their lovable spouses in the bed. Viagra pills for men sex has been faked by several unqualified pharmacists and more more available in unaccredited online pharmacies than the original Viagra pills. In this book you will comprehensively learn how to identify fake Viagra Pills from original Viagra, several ways of knowing deceptive Book/Guide written for Viagra and Viagra Banners online, the general existing dangerous active ingredients with their deadly side effects in counterfeit Viagra Pills, Where and How to Securely Buy Original Viagra Pills Online Affordably...and more others. Do not use Viagra Pills for men with Cialis. This Viagra Book contains everything you need to know about Viagra.
| Author | : Charles D. Ciccone |
| Publisher | : F.A. Davis |
| Total Pages | : 1217 |
| Release | : 2013-03-21 |
| Genre | : Medical |
| ISBN | : 0803640048 |
A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’s the perfect companion to Pharmacology in Rehabilitation, 4th Edition!
| Author | : Kumar Gadamasetti |
| Publisher | : CRC Press |
| Total Pages | : 534 |
| Release | : 2007-12-10 |
| Genre | : Medical |
| ISBN | : 1420008358 |
As pharmaceutical companies strive to develop safer medicines at a lower cost, they must keep pace with the rapid growth of technology and research methodologies. Defying the misconception of process chemistry as mere scale-up work, Process Chemistry in the Pharmaceutical Industry, Vol. 2: Challenges in an Ever Changing Climate explor
| Author | : Claire Lugnier |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 327 |
| Release | : 2008-02-04 |
| Genre | : Science |
| ISBN | : 1592598390 |
Research leaders in the PDE field describe new concepts and techniques for investigating the role of PDEs in orchestrating normal and pathophysiological responses. Presented in step-by-step detail, these readily reproducible methods allow the measurement of cyclic nucleotide variations in living cells, as well as their visualization in a spatio-temporal manner, the localization and characterization of their activities in tissues and living cells, and the assessment of targeted PDEs in creating specific tools and drugs.
| Author | : Randall Clint Baselt |
| Publisher | : |
| Total Pages | : 896 |
| Release | : 1989 |
| Genre | : Medical |
| ISBN | : |
Discussions include occurrence and usage, blood concentrations, metabolism and excretion, toxicity, analysis and bibliographic references.
| Author | : Jeffrey K. Aronson |
| Publisher | : Elsevier |
| Total Pages | : 841 |
| Release | : 2009-03-02 |
| Genre | : Medical |
| ISBN | : 0080932894 |
Elsevier now offers a series of derivative works based on the acclaimed Meylers Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing physician or health care clinician. Each year, heart disease kills more people than cancer. Patients are treated by a variety of specialists and primary care practitioners, depending on the organ system involved. This volume enables practitioners to assess the adverse effects of the complete range of drugs used in cardiovascular medicine, including antihypertensive drugs, and drugs used in the treatment of heart failure, angina, angina pectoris, and cardiac arrhythmia and enable practitioners to prescribe preventative treatments with medications such as blood pressure reducers, aspirin, and cholesterol-lowering drugs, as well as drugs used for more aggressive therapy.The material is drawn from the 15th edition of the internationally renowned encyclopedia, Meyler's Side Effects of Drugs, and the latest volumes in the companion series, Side Effects of Drugs Annuals. Drug names have usually been designated by their recommended or proposed International Non-proprietary Names (rINN or pINN); when those are not available, clinical names have been used. In some cases, brand names have been used.This volume is critical for any health professional involved in the administration of cardiovascular mediations. - Surpasses the Physician's Desk Reference © by including clinical case studies and independent expert analysis - Complete index of drug names - Most complete cross referencing of drug-drug interactions available - Extensive references to primary and secondary literature - Also includes information on adverse effects in pregnancy The book is divided into six sections: - Drugs used to treat hypertension, heart failure and angina pectoris - Diuretics – a general introduction to their adverse effects, followed by monographs on individual drugs - Antidysrhythmic drugs - a general introduction to their adverse effects, followed by monographs on individual drugs - Drugs that act on the cerebral and peripheral circulations - Anticoagulants, thrombolytic agents, and anti-platelet drugs - Cardiovascular adverse effects of non-cardiovascular drugs
