The Health Effects of Cannabis and Cannabinoids

The Health Effects of Cannabis and Cannabinoids
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 487
Release: 2017-03-31
Genre: Science
ISBN: 0309453070

Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Man, Medicine, and the State

Man, Medicine, and the State
Author: Wolfgang Uwe Eckart
Publisher: Franz Steiner Verlag
Total Pages: 304
Release: 2006
Genre: History
ISBN: 9783515087940

This anthology unites articles about different aspects of scientific human experiments in the course of World War I to the 1960s. The majority of them deals with the development of medicine and life sciences as well as the national research promotion under the Nazi regime and during World War II. Studies on human experiments of French, Japanese, and US-American research enlarge the perspective on a problem of obviously international range. These empirical studies are supplemented by articles on the legal evaluation of this behaviour of scientists, as well as on the resulting movement to formulate binding transnational ethical codes on behalf of human experiments.

Advancing Nuclear Medicine Through Innovation

Advancing Nuclear Medicine Through Innovation
Author: National Research Council
Publisher: National Academies Press
Total Pages: 173
Release: 2007-09-11
Genre: Medical
ISBN: 0309134153

Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Medicine, Science and Merck

Medicine, Science and Merck
Author: P. Roy Vagelos
Publisher: Cambridge University Press
Total Pages: 326
Release: 2004-01-05
Genre: Biography & Autobiography
ISBN: 9780521662956

This book traces the careers of Roy Vagelos, who eventually became the CEO of Merck and Co., Inc.

Ethics by Committee

Ethics by Committee
Author: Noortje Jacobs
Publisher: University of Chicago Press
Total Pages: 305
Release: 2022-08-26
Genre: Medical
ISBN: 0226819329

"Ethics boards have become obligatory passage points in today's medical science, and we forget how novel they really are. The use of humans in experiments is an age-old practice that records show goes back to at least the third century BC and, since the early modern period, as a practice it has become increasingly popular. Yet, in most countries around the world, hardly any formal checks and balances existed to govern the communal oversight of experiments involving human subjects until at least the 1960s. Ethics by Committee traces the rise of ethics boards for human experimentation in the second half of the twentieth century. Using the Netherlands as a case-study, Noortje Jacobs shows how the authority of physicians to make decisions about clinical research gave way in most developed nations to formal mechanisms of communal decision-making that served to regiment the behavior of individual researchers. This historically unprecedented change in scientific governance came out of a growing international wariness of medical research in the decades after World War II. Research ethics committees were originally intended not only to make human experimentation more ethical but also to raise its epistemic quality. By examining complex negotiations over the appropriate governance of human subjects research, Ethics by Committee advances our understanding not only of the history of research ethics and the randomized controlled trial but also, more broadly, of how liberal democracies in the late twentieth century have sought to resolve public concerns over charged issues in medicine and science"--

Medicine, Religion, and Health

Medicine, Religion, and Health
Author: Harold G Koenig
Publisher: Templeton Foundation Press
Total Pages: 246
Release: 2008-09-01
Genre: Religion
ISBN: 1599471418

Medicine, Religion, and Health: Where Science and Spirituality Meet will be the first title published in the new Templeton Science and Religion Series, in which scientists from a wide range of fields distill their experience and knowledge into brief tours of their respective specialties. In this, the series' maiden volume, Dr. Harold G. Koenig, provides an overview of the relationship between health care and religion that manages to be comprehensive yet concise, factual yet inspirational, and technical yet easily accessible to nonspecialists and general readers. Focusing on the scientific basis for integrating spirituality into medicine, Koenig carefully summarizes major trends, controversies, and the latest research from various disciplines and provides plausible and compelling theoretical explanations for what has thus far emerged in this relatively young field of study. Medicine, Religion, and Health begins by defining the principal terms and then moves on to a brief history of religion's role in medicine before delving into the current state of research. Koenig devotes several chapters to exploring the outcomes of specific studies in fields such as mental health, cardiovascular disease, and mortality. The book concludes with a review of the clinical applications derived from the research. Koenig also supplies several detailed appendices to aid readers of all levels looking for further information. Medicine, Religion, and Health will shed new light on critical contemporary issues. They will whet readers' appetites for more information on this fascinating, complex, and controversial area of research, clinical activity, and widespread discussion. It will find a welcome home on the bookshelves of students, researchers, clinicians, and other health professionals in a variety of disciplines.

The Integration of the Humanities and Arts with Sciences, Engineering, and Medicine in Higher Education

The Integration of the Humanities and Arts with Sciences, Engineering, and Medicine in Higher Education
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 283
Release: 2018-06-21
Genre: Education
ISBN: 0309470641

In the United States, broad study in an array of different disciplines â€"arts, humanities, science, mathematics, engineeringâ€" as well as an in-depth study within a special area of interest, have been defining characteristics of a higher education. But over time, in-depth study in a major discipline has come to dominate the curricula at many institutions. This evolution of the curriculum has been driven, in part, by increasing specialization in the academic disciplines. There is little doubt that disciplinary specialization has helped produce many of the achievement of the past century. Researchers in all academic disciplines have been able to delve more deeply into their areas of expertise, grappling with ever more specialized and fundamental problems. Yet today, many leaders, scholars, parents, and students are asking whether higher education has moved too far from its integrative tradition towards an approach heavily rooted in disciplinary "silos". These "silos" represent what many see as an artificial separation of academic disciplines. This study reflects a growing concern that the approach to higher education that favors disciplinary specialization is poorly calibrated to the challenges and opportunities of our time. The Integration of the Humanities and Arts with Sciences, Engineering, and Medicine in Higher Education examines the evidence behind the assertion that educational programs that mutually integrate learning experiences in the humanities and arts with science, technology, engineering, mathematics, and medicine (STEMM) lead to improved educational and career outcomes for undergraduate and graduate students. It explores evidence regarding the value of integrating more STEMM curricula and labs into the academic programs of students majoring in the humanities and arts and evidence regarding the value of integrating curricula and experiences in the arts and humanities into college and university STEMM education programs.

Principles of Translational Science in Medicine

Principles of Translational Science in Medicine
Author: Martin Wehling
Publisher: Academic Press
Total Pages: 365
Release: 2015-04-02
Genre: Science
ISBN: 0128007214

Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine. - Provides an in-depth description of novel tools for the assessment of translatability of trials to balance risk and improve projects at any given stage of product development - New chapters deal with translational issues in the fastest growing population (the elderly), case studies, translatability assessment tools, and advances in nanotherapies - Details IPR issues of translation, especially for public-private-partnerships - Contains contributions from world leaders in translational medicine, including the former NIH director and authorities from various European regulatory institutions

Marijuana As Medicine?

Marijuana As Medicine?
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 216
Release: 2000-12-30
Genre: Medical
ISBN: 0309065313

Some people suffer from chronic, debilitating disorders for which no conventional treatment brings relief. Can marijuana ease their symptoms? Would it be breaking the law to turn to marijuana as a medication? There are few sources of objective, scientifically sound advice for people in this situation. Most books about marijuana and medicine attempt to promote the views of advocates or opponents. To fill the gap between these extremes, authors Alison Mack and Janet Joy have extracted critical findings from a recent Institute of Medicine study on this important issue, interpreting them for a general audience. Marijuana As Medicine? provides patientsâ€"as well as the people who care for themâ€"with a foundation for making decisions about their own health care. This empowering volume examines several key points, including: Whether marijuana can relieve a variety of symptoms, including pain, muscle spasticity, nausea, and appetite loss. The dangers of smoking marijuana, as well as the effects of its active chemical components on the immune system and on psychological health. The potential use of marijuana-based medications on symptoms of AIDS, cancer, multiple sclerosis, and several other specific disorders, in comparison with existing treatments. Marijuana As Medicine? introduces readers to the active compounds in marijuana. These include the principal ingredient in Marinol, a legal medication. The authors also discuss the prospects for developing other drugs derived from marijuana's active ingredients. In addition to providing an up-to-date review of the science behind the medical marijuana debate, Mack and Joy also answer common questions about the legal status of marijuana, explaining the conflict between state and federal law regarding its medical use. Intended primarily as an aid to patients and caregivers, this book objectively presents critical information so that it can be used to make responsible health care decisions. Marijuana As Medicine? will also be a valuable resource for policymakers, health care providers, patient counselors, medical faculty and studentsâ€"in short, anyone who wants to learn more about this important issue.

The Science of Near-Death Experiences

The Science of Near-Death Experiences
Author: John C. Hagan
Publisher: University of Missouri Press
Total Pages: 184
Release: 2017-01-30
Genre: Body, Mind & Spirit
ISBN: 0826273688

What happens to consciousness during the act of dying? The most compelling answers come from people who almost die and later recall events that occurred while lifesaving resuscitation, emergency care, or surgery was performed. These events are now called near-death experiences (NDEs). As medical and surgical skills improve, innovative procedures can bring back patients who have traveled farther on the path to death than at any other time in history. Physicians and healthcare professionals must learn how to appropriately treat patients who report an NDE. It is estimated that more than 10 million people in the United States have experienced an NDE. Hagan and the contributors to this volume engage in evidence-based research on near-death experiences and include physicians who themselves have undergone a near-death experience. This book establishes a new paradigm for NDEs.