Sample Size And Positive False Discovery Rate Control For Multiple Testing
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Author | : Peter H. Westfall |
Publisher | : John Wiley & Sons |
Total Pages | : 382 |
Release | : 1993-01-12 |
Genre | : Mathematics |
ISBN | : 9780471557616 |
Combines recent developments in resampling technology (including the bootstrap) with new methods for multiple testing that are easy to use, convenient to report and widely applicable. Software from SAS Institute is available to execute many of the methods and programming is straightforward for other applications. Explains how to summarize results using adjusted p-values which do not necessitate cumbersome table look-ups. Demonstrates how to incorporate logical constraints among hypotheses, further improving power.
Author | : Alex Dmitrienko |
Publisher | : CRC Press |
Total Pages | : 323 |
Release | : 2009-12-08 |
Genre | : Mathematics |
ISBN | : 1584889853 |
Useful Statistical Approaches for Addressing Multiplicity IssuesIncludes practical examples from recent trials Bringing together leading statisticians, scientists, and clinicians from the pharmaceutical industry, academia, and regulatory agencies, Multiple Testing Problems in Pharmaceutical Statistics explores the rapidly growing area of multiple c
Author | : Alex Reinhart |
Publisher | : No Starch Press |
Total Pages | : 177 |
Release | : 2015-03-01 |
Genre | : Mathematics |
ISBN | : 1593276206 |
Scientific progress depends on good research, and good research needs good statistics. But statistical analysis is tricky to get right, even for the best and brightest of us. You'd be surprised how many scientists are doing it wrong. Statistics Done Wrong is a pithy, essential guide to statistical blunders in modern science that will show you how to keep your research blunder-free. You'll examine embarrassing errors and omissions in recent research, learn about the misconceptions and scientific politics that allow these mistakes to happen, and begin your quest to reform the way you and your peers do statistics. You'll find advice on: –Asking the right question, designing the right experiment, choosing the right statistical analysis, and sticking to the plan –How to think about p values, significance, insignificance, confidence intervals, and regression –Choosing the right sample size and avoiding false positives –Reporting your analysis and publishing your data and source code –Procedures to follow, precautions to take, and analytical software that can help Scientists: Read this concise, powerful guide to help you produce statistically sound research. Statisticians: Give this book to everyone you know. The first step toward statistics done right is Statistics Done Wrong.
Author | : Yosef Hochberg |
Publisher | : |
Total Pages | : 482 |
Release | : 1987-10-05 |
Genre | : Mathematics |
ISBN | : |
Offering a balanced, up-to-date view of multiple comparison procedures, this book refutes the belief held by some statisticians that such procedures have no place in data analysis. With equal emphasis on theory and applications, it establishes the advantages of multiple comparison techniques in reducing error rates and in ensuring the validity of statistical inferences. Provides detailed descriptions of the derivation and implementation of a variety of procedures, paying particular attention to classical approaches and confidence estimation procedures. Also discusses the benefits and drawbacks of other methods. Numerous examples and tables for implementing procedures are included, making this work both practical and informative.
Author | : Bradley Efron |
Publisher | : Cambridge University Press |
Total Pages | : |
Release | : 2012-11-29 |
Genre | : Mathematics |
ISBN | : 1139492136 |
We live in a new age for statistical inference, where modern scientific technology such as microarrays and fMRI machines routinely produce thousands and sometimes millions of parallel data sets, each with its own estimation or testing problem. Doing thousands of problems at once is more than repeated application of classical methods. Taking an empirical Bayes approach, Bradley Efron, inventor of the bootstrap, shows how information accrues across problems in a way that combines Bayesian and frequentist ideas. Estimation, testing and prediction blend in this framework, producing opportunities for new methodologies of increased power. New difficulties also arise, easily leading to flawed inferences. This book takes a careful look at both the promise and pitfalls of large-scale statistical inference, with particular attention to false discovery rates, the most successful of the new statistical techniques. Emphasis is on the inferential ideas underlying technical developments, illustrated using a large number of real examples.
Author | : Terry Speed |
Publisher | : CRC Press |
Total Pages | : 237 |
Release | : 2003-03-26 |
Genre | : Mathematics |
ISBN | : 0203011236 |
Although less than a decade old, the field of microarray data analysis is now thriving and growing at a remarkable pace. Biologists, geneticists, and computer scientists as well as statisticians all need an accessible, systematic treatment of the techniques used for analyzing the vast amounts of data generated by large-scale gene expression studies
Author | : Henry Scheffé |
Publisher | : John Wiley & Sons |
Total Pages | : 500 |
Release | : 1999-03-05 |
Genre | : Mathematics |
ISBN | : 9780471345053 |
Originally published in 1959, this classic volume has had a major impact on generations of statisticians. Newly issued in the Wiley Classics Series, the book examines the basic theory of analysis of variance by considering several different mathematical models. Part I looks at the theory of fixed-effects models with independent observations of equal variance, while Part II begins to explore the analysis of variance in the case of other models.
Author | : Thomas P. Hettmansperger |
Publisher | : |
Total Pages | : 360 |
Release | : 1984-07-30 |
Genre | : Mathematics |
ISBN | : |
A coherent, unified set of statistical methods, based on ranks, for analyzing data resulting from various experimental designs. Uses MINITAB, a statistical computing system for the implementation of the methods. Assesses the statistical and stability properties of the methods through asymptotic efficiency and influence curves and tolerance values. Includes exercises and problems.
Author | : Manish Bhattacharjee |
Publisher | : World Scientific |
Total Pages | : 311 |
Release | : 2011 |
Genre | : Science |
ISBN | : 9814329800 |
This unique volume provides self-contained accounts of some recent trends in Biostatistics methodology and their applications. It includes state-of-the-art reviews and original contributions. The articles included in this volume are based on a careful sel
Author | : Bradley Efron |
Publisher | : |
Total Pages | : 22 |
Release | : 2003 |
Genre | : |
ISBN | : |