Role Of Rco 1 In The Control Of Circadian Gene Expression And Metabolic Compensation Of The Neurospora Crassa Circadian Clock
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| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 198 |
| Release | : 2015-12-02 |
| Genre | : Science |
| ISBN | : 0128040793 |
Advances in Genetics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions. - Critically analyzes future directions for the study of clinical genetics - Written and edited by recognized leaders in the field - Presents new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics
| Author | : Marcio L. Rodrigues |
| Publisher | : Springer Nature |
| Total Pages | : 304 |
| Release | : 2019-09-03 |
| Genre | : Medical |
| ISBN | : 3030302377 |
This volume offers an overview of the various aspects involved in the ability of fungi to damage host cells, and discusses cutting-edge approaches to the study of fungal pathogenesis. The first chapter illustrate the key roles of glycans and pigments, the most abundant surface components in fungal cells, in their interactions with host cells. The connections between cellular physiology and fungal pathogenesis are then discussed in the following chapters. Physiology-related processes affecting pathogenesis include fungal secretion, morphological transitions, and response to light. In turn, the book illustrates mechanisms of damage to host cells using the Histoplasma capsulatum model of infection, and reviews the use of transcriptomic approaches to understand the mechanisms of interaction between fungal cells and host tissues. After a discussion of the immunological mechanisms underlying host susceptibility to fungal infections, the book’s closing contribution reviews the mechanisms of interaction between fungi and other microbes, and the impact of this association on fungal pathogenesis. Given its scope, the book will appeal to scientists in the fields of mycology, microbiology, infectious diseases, biology and medicine.
| Author | : J. Philipp Benz |
| Publisher | : Springer Nature |
| Total Pages | : 452 |
| Release | : 2020-10-28 |
| Genre | : Science |
| ISBN | : 3030499243 |
This fully revised third edition includes up-to-date topics and developments in the field, which has made tremendous strides since the publication of the second edition in 2004. Many novel techniques based on Next Generation Sequencing have sped up the analysis of fungi and major advances have been made in genome editing, leading to a deeper understanding of the genetics underlying cellular processes as well as their applicability. At the same time, the relevance of fungi is unbroken, both due to the serious threats to human health and welfare posed by fungal pests and pathogens, and to the many benefits that fungal biotechnology can offer for diverse emerging markets and processes that form the basis of the modern bioeconomy. With regard to these advances, the first section of this volume, Genetics, illustrates the basic genetic processes underlying inheritance, cell biology, metabolism and “lifestyles” of fungi. The second section, Biotechnology, addresses the applied side of fungal genetics, ranging from new tools for synthetic biology to the biotechnological potential of fungi from diverse environments. Gathering chapters written by reputed scientists, the book represents an invaluable reference guide for fungal biologists, geneticists and biotechnologists alike.
| Author | : David D. Perkins |
| Publisher | : Academic Press |
| Total Pages | : 337 |
| Release | : 2000-10-11 |
| Genre | : Science |
| ISBN | : 0080545505 |
The fungi have been major players in the molecular revolution that has transformed biology. Because they can be manipulated as microorganisms, yeast and Neurospora provide information that is difficult to acquire with plants and animals, and experimental findings with fungi often throw light on corresponding processes in plants and animals. The filamentous fungus Neurospora crassa has become a valuable model organism because of its favorable features for genetic analysis and because of the vast store of information that has been acquired during 75 years of research. This compendium provides researchers and students with a concise account of current knowledge about the genes and genome of Neurospora, setting the stage for research that will follow completion of the genome sequence.This book, which is fully documented and abundantly illustrated, will be an indispensable tool in any laboratory that uses fungi for research in molecular genetics, classical genetics, developmental genetics, or cell biology. - Molecular, genetic, and phenotypic information for over 1000 nuclear genes - Genetic maps - Linkage group assignments for 1000 loci - 2300 references, 68 figures - Guide to electronic and other sources of information - Summary information on the mitochondrial genome - cDNAs identified from different stages of life - Classical, cytogenetic, and molecular data, anticipating completion of the genome sequence
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 269 |
| Release | : 2011-09-16 |
| Genre | : Science |
| ISBN | : 0123876982 |
This latest volume in Advances in Genetics covers the genetics of Circadian rhythms. With an international group of authors this volume is the latest offering in this widely praised series.
| Author | : J. Richard Dickinson |
| Publisher | : CRC Press |
| Total Pages | : 476 |
| Release | : 2004-04-27 |
| Genre | : Science |
| ISBN | : 0203503864 |
Since the publication of the best-selling first edition, much has been discovered about Saccharomyces cerevisiae, the single-celled fungus commonly known as baker's yeast or brewer's yeast that is the basis for much of our understanding of the molecular and cellular biology of eukaryotes. This wealth of new research data demands our attention and r
| Author | : |
| Publisher | : |
| Total Pages | : 466 |
| Release | : 1996 |
| Genre | : Fungi |
| ISBN | : |
| Author | : Jerry L. Workman |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 594 |
| Release | : 2013-12-04 |
| Genre | : Medical |
| ISBN | : 1461486246 |
While there has been an increasing number of books on various aspects of epigenetics, there has been a gap over the years in books that provide a comprehensive understanding of the fundamentals of chromatin. Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. Its primary function is to package DNA to fit into the cell, to strengthen the DNA to prevent damage, to allow mitosis and meiosis, and to control the expression of genes and DNA replication. The audience for this book is mainly newly established scientists and graduate students. Rather than going into the more specific areas of recent research on chromatin the chapters in this book give a strong, updated groundwork about the topic. Some the fundamentals that this book will cover include the structure of chromatin and biochemistry and the enzyme complexes that manage it.
| Author | : Anita Göndör |
| Publisher | : Academic Press |
| Total Pages | : 498 |
| Release | : 2016-10-25 |
| Genre | : Science |
| ISBN | : 0128034025 |
Chromatin Regulation and Dynamics integrates knowledge on the dynamic regulation of primary chromatin fiber with the 3D nuclear architecture, then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes. The final chapters discuss the many ways chromatin dynamics can synergize to fundamentally contribute to the development of complex diseases. Chromatin dynamics, which is strategically positioned at the gene-environment interface, is at the core of disease development. As such, Chromatin Regulation and Dynamics, part of the Translational Epigenetics series, facilitates the flow of information between research areas such as chromatin regulation, developmental biology, and epidemiology by focusing on recent findings of the fast-moving field of chromatin regulation. - Presents and discusses novel principles of chromatin regulation and dynamics with a cross-disciplinary perspective - Promotes crosstalk between basic sciences and their applications in medicine - Provides a framework for future studies on complex diseases by integrating various aspects of chromatin biology with cellular metabolic states, with an emphasis on the dynamic nature of chromatin and stochastic principles - Integrates knowledge on the dynamic regulation of primary chromatin fiber with 3D nuclear architecture, then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes
| Author | : Tilo Strutz |
| Publisher | : Springer Vieweg |
| Total Pages | : 0 |
| Release | : 2015-12-16 |
| Genre | : Technology & Engineering |
| ISBN | : 9783658114558 |
The subject of data fitting bridges many disciplines, especially those traditionally dealing with statistics like physics, mathematics, engineering, biology, economy, or psychology, but also more recent fields like computer vision. This book addresses itself to engineers and computer scientists or corresponding undergraduates who are interested in data fitting by the method of least-squares approximation, but have no or only limited pre-knowledge in this field. Experienced readers will find in it new ideas or might appreciate the book as a useful work of reference. Familiarity with basic linear algebra is helpful though not essential as the book includes a self-contained introduction and presents the method in a logical and accessible fashion. The primary goal of the text is to explain how data fitting via least squares works. The reader will find that the emphasis of the book is on practical matters, not on theoretical problems. In addition, the book enables the reader to design own software implementations with application-specific model functions based on the comprehensive discussion of several examples. The text is accompanied with working source code in ANSI-C for fitting with weighted least squares including outlier detection. Among others the book covers following topics * fitting of linear and nonlinear functions with one- or multi-dimensional variables * weighted least-squares * outlier detection * evaluation of the fitting results * different optimisation strategies * combined fitting of different model functions * total least-squares approach with multi-dimensional conditions
