Brain Development in Drosophila melanogaster

Brain Development in Drosophila melanogaster
Author: Gerhard Martin Technau
Publisher: Springer Science & Business Media
Total Pages: 173
Release: 2009-01-08
Genre: Medical
ISBN: 0387782613

The fruitfly Drosophila melanogaster is an ideal model system to study processes of the central nervous system This book provides an overview of some major facets of recent research on Drosophila brain development.

Development and Neurobiology of Drosophila

Development and Neurobiology of Drosophila
Author: O. Siddiqi
Publisher: Springer Science & Business Media
Total Pages: 487
Release: 2013-11-11
Genre: Science
ISBN: 1468479687

There is no multicellular animal whose genetics is so well understood as Drosophila melanogaster. An increasing number of biologists have, therefore, turned to the fruitfly in pursuit of such diverse areas as the molecular biology of eukaryotic cells, development and neurobiology. Indeed there are signs that Dro sophila may soon become the most central organism in biqlogy for genetic analysis of complex problems. The papers in this collection were presented at a conference on Development and Behavior of Drosophila held at the Tata Insti tute of Fundamental Research from 19th to 22nd December, 1979. The volume reflects the commonly shared belief of the participants that Drosophila has as much to contribute to biology in the future as it has in the past. We hope it will be of interest not merely to Dro sophilists but to all biologists. We thank Chetan Premani, Anil Gupta, K.S. Krishnan, Veronica Rodrigues, Hemant Chikermane and K. Vijay Raghavan for help with recording and transcription of the proceedings and Vrinda Nabar and K.V. Hareesh for editorial assistance. We thank Samuel Richman, Thomas Schmidt-Glenewinkel and T.R. Venkatesh for their valuable assistance in proofreading the manuscripts, and we also thank Patricia Rank for her excellent effort in the preparation of the final manuscripts. The conference was supported by a grant from Sir Dorabji Tata Trust.

The Embryonic Development of Drosophila melanogaster

The Embryonic Development of Drosophila melanogaster
Author: Jose A. Campos-Ortega
Publisher: Springer Science & Business Media
Total Pages: 237
Release: 2013-03-09
Genre: Science
ISBN: 3662024543

" . . . but our knowledge is so weak that no philosoph er will ever be able to completely explore the nature of even a fly . . . " * Thornas Aquinas "In Syrnbolurn Apostolorum" 079 RSV p/96 This is a monograph on embryogenesis of the fruit fly Drosophi la melanogaster conceived as a reference book on morphology of embryonie development. A monograph of this extent and con tent is not yet available in the literature of Drosophila embryolo gy, and we believe that there is areal need for it. Thanks to the progress achieved during the last ten years in the fields of devel opmental and molecular genetics, work on Drosophila develop ment has considerably expanded creating an even greater need for the information that we present here. Our own interest for wildtype embryonie development arose several years ago, when we began to study the development of mutants. While those studies were going on we repeatedly had occasion to state in sufficiencies in the existing literature about the embryology of the wildtype, so that we undertook investigating many of these problems by ourselves. Convinced that several of our colleagues will have encountered similar difficulties we decided to publish the present monograph. Although not expressely recorded, Thomas Aquinas probably referred to the domestic fly and not to the fruit fly. Irrespective of which fly he meant, however, we know that Thomas was right in any case.

Mouse Brain Development

Mouse Brain Development
Author: Andre M. Goffinet
Publisher: Springer Science & Business Media
Total Pages: 347
Release: 2012-08-10
Genre: Science
ISBN: 3540480021

Our understanding of the molecular mechanisms involved in mammalian brain development remains limited. However, the last few years have wit nessed a quantum leap in our knowledge, due to technological improve ments, particularly in molecular genetics. Despite this progress, the available body of data remains mostly phenomenological and reveals very little about the grammar that organizes the molecular dictionary to articulate a pheno type. Nevertheless, the recent progress in genetics will allow us to contem plate, for the first time, the integration of observation into a coherent view of brain development. Clearly, this may be a major challenge for the next century, and arguably is the most important task of contemporary develop mental biology. The purpose of the present book is to provide an overview that syn thesizes up-to-date information on selected aspects of mouse brain devel opment. Given the format, it was not possible to cover all aspects of brain development, and many important subjects are missing. The selected themes are, to a certain extent, subjective and reflect the interests of the contributing authors. Examples of major themes that are not covered are peripheral nervous system development, including myelination, the development of the hippocampus and several other CNS structures, as well as the developmental function of some important morphoregulatory molecules.

Robustness in Statistics

Robustness in Statistics
Author: Robert L. Launer
Publisher: Academic Press
Total Pages: 313
Release: 2014-05-12
Genre: Mathematics
ISBN: 1483263363

Robustness in Statistics contains the proceedings of a Workshop on Robustness in Statistics held on April 11-12, 1978, at the Army Research Office in Research Triangle Park, North Carolina. The papers review the state of the art in statistical robustness and cover topics ranging from robust estimation to the robustness of residual displays and robust smoothing. The application of robust regression to trajectory data reduction is also discussed. Comprised of 14 chapters, this book begins with an introduction to robust estimation, paying particular attention to iteration schemes and error structure of estimators. Sensitivity and influence curves as well as their connection with jackknife estimates are described. The reader is then introduced to a simple analog of trimmed means that can be used for studying residuals from a robust point-of-view; a class of robust estimators (called P-estimators) based on the location and scale-invariant Pitman estimators of location; and robust estimation in the presence of outliers. Subsequent chapters deal with robust regression and its use to reduce trajectory data; tests for censoring of extreme values, especially when population distributions are incompletely defined; and robust estimation for time series autoregressions. This monograph should be of interest to mathematicians and statisticians.

Mayo Clinic Medical Neurosciences

Mayo Clinic Medical Neurosciences
Author: Eduardo E. Benarroch
Publisher: Oxford University Press
Total Pages: 850
Release: 2017-11-06
Genre: Medical
ISBN: 0190209429

Fully updated and revised according to student feedback, the sixth edition of Mayo Clinic Medical Neurosciences: Organized by Neurologic System and Level provides a systematic approach to anatomy, physiology, and pathology of the nervous system inspired by the neurologist's approach to solving clinical problems. This volume has 4 sections: 1) an overview of the neurosciences necessary for understanding anatomical localization and pathophysiologic characterization of neurologic disorders; 2) an approach to localizing lesions in the 7 longitudinal systems of the nervous system; 3) an approach to localizing lesions in the 4 horizontal levels of the nervous system; and 4) a collection of clinical problems. This book provides the neuroscience framework to support the neurologist in a clinical setting and is also a great resource for neurology and psychiatry board certifications. This is the perfect guide for all medical students and neurology, psychiatry, and physical medicine residents at early stages of training. New to This Edition - A chapter devoted to multiple-choice questions for self-assessment - Discussion of emerging concepts in molecular, cellular, and system neurosciences - New chapters on emotion and consciousness systems - Incorporation of new discoveries in neuroimaging and an appendix for tables of medications commonly used to treat neurologic disorders

The Neural Crest

The Neural Crest
Author: Nicole Le Douarin
Publisher: Cambridge University Press
Total Pages: 494
Release: 1999-11-28
Genre: Medical
ISBN: 9780521620109

This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.

Clinical Neuroembryology

Clinical Neuroembryology
Author: Hans J. ten Donkelaar
Publisher: Springer Science & Business Media
Total Pages: 544
Release: 2006-09-07
Genre: Medical
ISBN: 3540346597

Progress in developmental neurobiology and advances in (neuro) genetics have been spectacular. The high resolution of modern imaging techniques applicable to developmental disorders of the human brain and spinal cord have created a novel insight into the developmental history of the central nervous system (CNS). This book provides a comprehensive overview of the development of the human CNS in the context of its many developmental disorders. It provides a unique combination of data from human embryology, animal research and developmental neuropathology, and there are more than 400 figures in over a hundred separate illustrations.