Quantification Of Volumetric Changes Of Brain In Neurodegenerative Diseases Using Magnetic Resonance Imaging And Stereology
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| Author | : Raymond Chuen-Chung Chang |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 574 |
| Release | : 2011-12-09 |
| Genre | : Medical |
| ISBN | : 953307485X |
Neurodegenerative Diseases - Processes, Prevention, Protection and Monitoring focuses on biological mechanisms, prevention, neuroprotection and even monitoring of disease progression. This book emphasizes the general biological processes of neurodegeneration in different neurodegenerative diseases. Although the primary etiology for different neurodegenerative diseases is different, there is a high level of similarity in the disease processes. The first three sections introduce how toxic proteins, intracellular calcium and oxidative stress affect different biological signaling pathways or molecular machineries to inform neurons to undergo degeneration. A section discusses how neighboring glial cells modulate or promote neurodegeneration. In the next section an evaluation is given of how hormonal and metabolic control modulate disease progression, which is followed by a section exploring some preventive methods using natural products and new pharmacological targets. We also explore how medical devices facilitate patient monitoring. This book is suitable for different readers: college students can use it as a textbook; researchers in academic institutions and pharmaceutical companies can take it as updated research information; health care professionals can take it as a reference book, even patients' families, relatives and friends can take it as a good basis to understand neurodegenerative diseases.
| Author | : P. R. Mouton |
| Publisher | : John Wiley & Sons |
| Total Pages | : 305 |
| Release | : 2013-11-12 |
| Genre | : Medical |
| ISBN | : 1118444183 |
Stereological methods provide researchers with unparalleled quantitative data from tissue samples and allow for well-evidenced research advances in a broad range of scientific fields. Presenting a concise introduction to the methodology and application of stereological research in neuroscience, Neurostereology provides a fuller understanding of the use of these methods in research and a means for replicating successful scientific approaches. Providing sound footing for future research, Neurostereology is a useful tool for basic and clinical researchers and advanced students looking to integrate these methods into their research.
| Author | : M. Filippi |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 233 |
| Release | : 2008-02-01 |
| Genre | : Medical |
| ISBN | : 8847003911 |
Written by world-renowned scientists, the volume provides a state-of-the-art on the most recent MRI techniques related to MS, and it is an indispensable tool for all those working in this field. The context in which this book exists is that there is an increasing perception that modern MR methodologies should be more extensively employed in clinical trials to derive innovative information.
| Author | : Giorgio A. Ascoli |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 466 |
| Release | : 2002-07-01 |
| Genre | : Medical |
| ISBN | : 1592592759 |
In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models.
| Author | : Paul J. Harrison |
| Publisher | : |
| Total Pages | : 402 |
| Release | : 2000-08-24 |
| Genre | : Medical |
| ISBN | : |
What is schizophrenia? This is one of the most controversial questions in psychiatry and mental health research; however, in the last twenty years, there have been significant advances in our understanding of the topic. This book provides a balanced, comprehensive and up-to-date overview of the neuropathology of schizophrenia and its interpretation, covering the latest evidence derived from all fields of research, from brain scans to microscopy. The authors include many of the foremost international authorities in this rapidly developing field.
| Author | : Daniel Laskowitz |
| Publisher | : CRC Press |
| Total Pages | : 388 |
| Release | : 2016-04-21 |
| Genre | : Medical |
| ISBN | : 1498766579 |
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
| Author | : Joachim Ohser |
| Publisher | : John Wiley & Sons |
| Total Pages | : 420 |
| Release | : 2000-12-19 |
| Genre | : Mathematics |
| ISBN | : 0471974862 |
The investigation of the origin and formation of microstructures and the effect that microstructure has on the properties of materials are important issues in materials science and technology. Geometrical analysis is often the key to understanding the formation of microstructures and the resulting material properties. The authors make use of mathematical morphology, spatial statistics, image processing, stereology and stochastic geometry to analyze microstructures arising in materials science. * Quantitative microstructure analysis is one of the most successful experimental techniques in materials science * Uses examples to demonstrate the techniques * Program code included enables the reader to apply the numerous algorithms * Accessible to material scientists with limited statistical knowledge Primarily aimed at applied materials scientists, the book will also appeal to those working and researching in earth sciences, material technology, mineralogy, petrography, image analysis, cytology and biology.
| Author | : Katrin Amunts |
| Publisher | : Springer Nature |
| Total Pages | : 159 |
| Release | : 2021-07-20 |
| Genre | : Computers |
| ISBN | : 3030824276 |
This open access book constitutes revised selected papers from the 4th International Workshop on Brain-Inspired Computing, BrainComp 2019, held in Cetraro, Italy, in July 2019. The 11 papers presented in this volume were carefully reviewed and selected for inclusion in this book. They deal with research on brain atlasing, multi-scale models and simulation, HPC and data infra-structures for neuroscience as well as artificial and natural neural architectures.
| Author | : Markus Kipp |
| Publisher | : MDPI |
| Total Pages | : 330 |
| Release | : 2021-01-06 |
| Genre | : Medical |
| ISBN | : 3039436899 |
The adult vertebrate central nervous system mainly consists of neurons, astrocytes, microglia cells, and oligodendrocytes. Oligodendrocytes, the myelin-forming cells of the CNS, are subjected to cell stress and subsequent death in a number of metabolic or inflammatory disorders, among which multiple sclerosis (MS) is included. This disease is associated with the development of large demyelinated plaques, oligodendrocyte destruction, and axonal degeneration, paralleled by the activation of astrocytes and microglia as well as the recruitment of peripheral immune cells to the site of tissue injury. Of note, viable oligodendrocytes and an intact myelin sheath are indispensable for neuronal health. For example, it has been shown that oligodendrocytes provide nutritional support to neurons, fast axonal transport depends on proper oligodendrocyte function, and mice deficient in mature myelin proteins eventually display severe neurodegeneration. This Special Issue contains a collection of highly relevant primary research articles as well as review articles focusing on the development, physiology, and pathology of the oligodendrocyte–axon–myelin unit.
| Author | : George Paxinos |
| Publisher | : Academic Press |
| Total Pages | : 602 |
| Release | : 2021-11-18 |
| Genre | : Medical |
| ISBN | : 0128189630 |
The complement to The Rat Brain in Stereotaxic Coordinates, Chemoarchitectonic Atlas of the Rat Brain, Third Edition, features a single brain series of high-quality plates stained with eight different markers, extensively annotated and labelled throughout. Plates from the previous edition of Chemoarchitectonic Atlas of the Rat Brain have been re-scanned at high resolution and are shown in color. Labeled structures have been revised, corrected, and updated, providing users with a streamlined, up-to-date, and highly accurate compendium of chemical markers. Researchers with a need to understand the detailed organization of the rat brain as well as structure/function relationships will need this atlas and its array of stains. - Provides an archive of chemical markers in the rat brain used in many areas of research - Discusses primary data to help researchers identify structures in their own preparations from neuroanatomical, physiological, neuropharmacological, and gene expression studies - Accompanies the gold standard reference on the neuroanatomy of the nervous system of the most important model animal in neuroscience and experimental psychology - Covers both the rat forebrain and the rat brainstem - Thoroughly revised identification of structures following the new data from The Rat Brain in Stereotaxic Coordinates 7th edition and the Chick Brain in Stereotaxic Coordinates 2nd edition - Includes the Expert Consult eBook version, compatible with PC, Mac, and most mobile devices and eReaders, which allows readers to browse, search, and interact with content
