The invitation to write a foreword for this book came at an opportune time in the development of the field of psychedelic-assisted therapy, amid the emergence of the future iteration of mental health services, delivered by the promises of the psychedelic renaissance. Also alive in this context are the substantial individual, social and cultural repercussions of a global pandemic on mental health and human behavior. A growing body of research shows encouraging clinical results in treating trauma, depression, demoralization, end-of-life existential issues, addiction, and eating disorders using MDMA, psilocybin, ketamine, and other psychedelic medications. However, the field of psychedelic-assisted therapy has gained accelerated support from donors, the medical establishment, and corporate investors in recent years. Along with the enthusiasm, recognition, funding, and media coverage directed toward psychedelic-assisted therapy, ethical standards; the lack of adequate training; and issues of accessibility, sustainability, diversity and inclusion are increasingly becoming part of the movement's forefront. These gaps in the emerging field highlight the need for more guidance and structure around ethical, clinical, and social considerations for these innovative treatments. This book can serve as a cornerstone for the field of psychedelic-assisted therapy at this time. This essential contribution offers a depth-oriented, somatic and relational therapeutic approach, emphasizing the imperative of ethical standards, the relevance of the therapeutic use of touch, the significance of the unconscious in the construction of symbolic meaning and intersubjective processes, and the need for trauma -informed approaches while centering liberation psychology and decolonial practices. The topics covered in this book and the themes embraced by the authors are of great relevance and are not yet comprehensively articulated in existing publications on psychedelic-assisted therapy. The diverse authors of this book approach their chapters based on their diverse social and cultural identities, as well as their extensive clinical experience providing psychedelic-assisted therapy in government-approved clinical research, private practice, and nonprofit organization settings. Their contributions aim at a vision of psychedelic-assisted therapy centered on decolonial practices, attuned to the somatic, imaginal, cultural and relational dimensions of being, allowing the emergence of transpersonal processes. Each chapter elaborates practical and theoretical aspects of this treatment modality through a unique theoretical framework, providing inspiration and guidance to readers working in this field as well as those compelled to psychedelic work for personal transformation.