Protein Aggregation A Complete Guide
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| Author | : Wei Wang |
| Publisher | : John Wiley & Sons |
| Total Pages | : 400 |
| Release | : 2010-12-28 |
| Genre | : Medical |
| ISBN | : 1118043588 |
This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has been mostly experimental. The knowledge in this book can greatly help pharmaceutical scientists in the development of therapeutic proteins, and also instigate further scientific investigations in this area. This book fills such a need by providing an overview on the causes, consequences, characterization, and control of the aggregation of therapeutic proteins.
| Author | : Hanns-Christian Mahler |
| Publisher | : John Wiley & Sons |
| Total Pages | : 480 |
| Release | : 2011-12-20 |
| Genre | : Medical |
| ISBN | : 1118150562 |
This book describes how to address the analysis of aggregates and particles in protein pharmaceuticals, provides a comprehensive overview of current methods and integrated approaches used to quantify and characterize aggregates and particles, and discusses regulatory requirements. Analytical methods covered in the book include separation, light scattering, microscopy, and spectroscopy.
| Author | : Exam |
| Publisher | : Elsevier India |
| Total Pages | : 756 |
| Release | : 2009 |
| Genre | : |
| ISBN | : 9788131216200 |
" 4 Volumes covering 19 subjects with an extensive summary on each subject " 10 years (1999 - 2008) question papers of All India PGMEE and AIIMS PGMEE with answers and explanations This book offers you 6 months FREE access to the Elsevier ExamZoneTM website specially designed for PGME preparations" Monthly Mock Tests with answers, explanations and a subject wise performance summary " Simulated tests of recently concluded PGME exams" Ask an Expert to clarify your doubts " List of medical institutes offering PG courses " Exam calender updates you with the upcoming exams, application availability, due date for form submissions, etc. Elsevier ExamZoneTM is a brand developed to focus on exam preparatory materials and testing tools.All rights in the trademark ExamZone" are reserved with Reed Elsevier India Pvt. Ltd
| Author | : Robert Mills |
| Publisher | : Robert Mills |
| Total Pages | : 165 |
| Release | : 101-01-01 |
| Genre | : Medical |
| ISBN | : |
This process involves amino acids, the deficiency of which leads to a lack of peptides. This often provokes premature aging and increases Peptides are protein combinations required by the body no less than B vitamins. They are directly involved in many internal processes of the body, mainly related to metabolism and the absorption of micronutrients. Due to modern diets, many people are deficient in them. This workbook includes: · The basic concept of peptides · How peptides work in the skin · Benefits of peptide · Peptides in hair · Peptides in food · And a lot of other useful information. This means you can achieve remarkable results, such as accelerated healing post-injury, enhanced performance in daily activities, and a visibly rejuvenated appearance, with minimal risk of dependency or adverse effects. Showing you exactly how these therapies can be a game-changer in your health strategy.
| Author | : VIRUTI SHIVAN |
| Publisher | : Viruti Satyan Shivan |
| Total Pages | : 221 |
| Release | : |
| Genre | : Science |
| ISBN | : |
Dive into the groundbreaking realm of bioinformatics with "Bioinformatics Scientist- The Comprehensive Guide," your ultimate resource for mastering the intricacies of biological data analysis. This guide demystifies the complex world of genetic codes, protein databases, and computational biology, providing an unparalleled journey into the heart of modern biology. Without the need for images or illustrations, the book focuses purely on the rich, detailed narrative and insightful analyses, ensuring an engaging and immersive reading experience. Whether you're a budding scientist, a seasoned researcher, or simply a curious mind, this book promises to transform your understanding of biology, offering a fresh perspective on how data can unlock the mysteries of life itself. In an era where information is abundant yet clarity is scarce, this comprehensive guide stands out by not only covering the technical aspects of bioinformatics but also by connecting the dots between computational techniques and their real-world applications in solving biological problems. Through vivid hypothetical scenarios and personal anecdotes from experts in the field, readers are taken on a captivating journey from the basics of DNA sequencing to the forefront of genetic research. The book emphasizes the critical role of bioinformatics in advancing healthcare, environmental conservation, and our understanding of evolution, making it an essential addition to the library of anyone looking to make a mark in the biological sciences.
| Author | : Andrzej Stanisław Cieplak |
| Publisher | : Springer Nature |
| Total Pages | : 673 |
| Release | : 2022-10-30 |
| Genre | : Science |
| ISBN | : 1071625977 |
The volume details techniques, methods, and conceptual developments to further the study of protein aggregation with emphasis on the pleiomorphic proteins implicated in etiology of neurodegeneration. Chapters guide readers through in vitro and in vivo studies of fibrillization and liquid-liquid phase separation processes, and offer a comprehensive account of the state-of-art of structural studies of protein aggregation. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Protein Aggregation: Methods and Protocols aims to be useful and practical guide to new researchers and experts looking to expand their knowledge.
| Author | : Jennifer J. McManus |
| Publisher | : Humana |
| Total Pages | : 266 |
| Release | : 2020-08-08 |
| Genre | : Science |
| ISBN | : 9781493996803 |
This volume explores experimental and computational approaches to measuring the most widely studied protein assemblies, including condensed liquid phases, aggregates, and crystals. The chapters in this book are organized into three parts: Part One looks at the techniques used to measure protein-protein interactions and equilibrium protein phases in dilute and concentrated protein solutions; Part Two describes methods to measure kinetics of aggregation and to characterize the assembled state; and Part Three details several different computational approaches that are currently used to help researchers understand protein self-assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Protein Self-Assembly: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this developing field.
| Author | : Renuka Raja Rao |
| Publisher | : Pearson Education India |
| Total Pages | : 456 |
| Release | : 2011 |
| Genre | : Foreign study |
| ISBN | : 9788131731963 |
| Author | : Timir Tripathi |
| Publisher | : Academic Press |
| Total Pages | : 716 |
| Release | : 2022-01-14 |
| Genre | : Science |
| ISBN | : 0323902650 |
Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application. - Presents a thorough overview of the latest and emerging methods and technologies for protein study - Explores biophysical techniques, including nuclear magnetic resonance, X-ray crystallography, and cryo-electron microscopy - Includes computational and machine learning methods - Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins
| Author | : Vladimir N. Uversky |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 538 |
| Release | : 2007-05-26 |
| Genre | : Medical |
| ISBN | : 0387365346 |
The second volume continues to fill the gap in protein review and protocol literature. It does this while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. The focus of Part B is the molecular basis of differential disorders.
