Proceedings Of The 5th Asia Pacific Bioinformatics Conference
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| Author | : David Sankoff |
| Publisher | : Imperial College Press |
| Total Pages | : 391 |
| Release | : 2007 |
| Genre | : Computers |
| ISBN | : 1860947999 |
High-throughput sequencing and functional genomics technologies have given us the human genome sequence as well as those of other experimentally, medically, and agriculturally important species, and have enabled large-scale genotyping and gene expression profiling of human populations. Databases containing large numbers of sequences, polymorphisms, structures, and gene expression profiles of normal and diseased tissues are being rapidly generated for human and model organisms. Bioinformatics is thus rapidly growing in importance in the annotation of genomic sequences; the understanding of the interplay among and between genes and proteins; the analysis of genetic variability of species; the identification of pharmacological targets; and the inference of evolutionary origins, mechanisms, and relationships. This proceedings volume contains an up-to-date exchange of knowledge, ideas, and solutions to conceptual and practical issues of bioinformatics by researchers, professionals, and industrial practitioners at the 5th Asia-Pacific Bioinformatics Conference held in Hong Kong in January 2007.
| Author | : Francis Y L Chin |
| Publisher | : World Scientific |
| Total Pages | : 391 |
| Release | : 2007-01-12 |
| Genre | : Science |
| ISBN | : 1908979291 |
High-throughput sequencing and functional genomics technologies have given us the human genome sequence as well as those of other experimentally, medically, and agriculturally important species, and have enabled large-scale genotyping and gene expression profiling of human populations. Databases containing large numbers of sequences, polymorphisms, structures, and gene expression profiles of normal and diseased tissues are being rapidly generated for human and model organisms. Bioinformatics is thus rapidly growing in importance in the annotation of genomic sequences; the understanding of the interplay among and between genes and proteins; the analysis of genetic variability of species; the identification of pharmacological targets; and the inference of evolutionary origins, mechanisms, and relationships. This proceedings volume contains an up-to-date exchange of knowledge, ideas, and solutions to conceptual and practical issues of bioinformatics by researchers, professionals, and industrial practitioners at the 5th Asia-Pacific Bioinformatics Conference held in Hong Kong in January 2007./a
| Author | : Alvis Brazma |
| Publisher | : World Scientific |
| Total Pages | : 413 |
| Release | : 2007-12-21 |
| Genre | : Science |
| ISBN | : 1908978953 |
High-throughput sequencing and functional genomics technologies have given us the human genome sequence as well as those of other experimentally, medically, and agriculturally important species, thus enabling large-scale genotyping and gene expression profiling of human populations. Databases containing large numbers of sequences, polymorphisms, structures, metabolic pathways, and gene expression profiles of normal and diseased tissues are rapidly being generated for human and model organisms. Bioinformatics is therefore gaining importance in the annotation of genomic sequences; the understanding of the interplay among and between genes and proteins; the analysis of the genetic variability of species; the identification of pharmacological targets; and the inference of evolutionary origins, mechanisms, and relationships. This proceedings volume contains an up-to-date exchange of knowledge, ideas, and solutions to conceptual and practical issues of bioinformatics by researchers, professionals, and industry practitioners at the 6th Asia-Pacific Bioinformatics Conference held in Kyoto, Japan, in January 2008./a
| Author | : Hon Wai Leong |
| Publisher | : World Scientific |
| Total Pages | : 145 |
| Release | : 2008-07-07 |
| Genre | : Science |
| ISBN | : 1908978740 |
Research in the field of gene regulation is evolving rapidly in the ever-changing scientific environment. Advances in microarray techniques and comparative genomics have enabled more comprehensive studies of regulatory genomics. The study of genomic binding locations of transcription factors has enabled a more comprehensive modeling of regulatory networks. In addition, complete genomic sequences and comparison of numerous related species have demonstrated the conservation of non-coding DNA sequences, which often provide evidence for cis-regulatory binding sites. Systematic methods to decipher the regulatory mechanism are also crucial for corroborating these regulatory networks; key to these methods are motif discovery algorithms that can help predict cis-regulatory elements. These DNA-motif discovery programs are becoming more sophisticated and are beginning to leverage evidence from comparative genomics. These topics and more were discussed at the 3rd Annual RECOMB Workshop on Regulatory Genomics, which brought together more than 90 attendees and included about 22 excellent talks from leading researchers in the field. This proceedings volume contains ten selected, original manuscripts that were presented during the workshop./a
| Author | : Dong Xu |
| Publisher | : World Scientific |
| Total Pages | : 246 |
| Release | : 2008-08-11 |
| Genre | : Science |
| ISBN | : 1908978716 |
Many biological systems and objects are intrinsically fuzzy as their properties and behaviors contain randomness or uncertainty. In addition, it has been shown that exact or optimal methods have significant limitation in many bioinformatics problems. Fuzzy set theory and fuzzy logic are ideal to describe some biological systems/objects and provide good tools for some bioinformatics problems. This book comprehensively addresses several important bioinformatics topics using fuzzy concepts and approaches, including measurement of ontological similarity, protein structure prediction/analysis, and microarray data analysis. It also reviews other bioinformatics applications using fuzzy techniques./a
| Author | : Ying Xu |
| Publisher | : World Scientific |
| Total Pages | : 494 |
| Release | : 2008 |
| Genre | : Medical |
| ISBN | : 1860949827 |
Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses.
| Author | : Don Kulasiri |
| Publisher | : #N/A |
| Total Pages | : 363 |
| Release | : 2017-06-09 |
| Genre | : Science |
| ISBN | : 1786343398 |
This book demonstrates the power of mathematical thinking in understanding the biological complexity that exists within the brain. It looks at the latest research on modelling of biochemical pathways within synapses, and provides a clear background for the study of mathematical models related to systems biology. Discussion then focusses on developments in computational models based on networks linked to synaptic plasticity. The models are used to understand memory formation and impairment and they provide a mathematical basis for memory research.Computational Systems Biology of Synaptic Plasticity is a valuable source of knowledge to postgraduate students and researchers in computational systems biology, and as a reference book for various techniques that are needed in modelling biological processes.
| Author | : Ziling Wang |
| Publisher | : World Scientific |
| Total Pages | : 304 |
| Release | : 2018-07-02 |
| Genre | : Science |
| ISBN | : 1848169264 |
This is a handbook of methods and protocols for biologists. It aimed at undergraduate, graduate students and researchers originally trained in biological or medical sciences who need to know how to access the data archives of genomes, proteins, metabolites, gene expression profiles and the questions these data and tools can answer. For each chapter, the conceptual and experimental background is provided, together with specific guidelines for handling raw data, including preprocessing and analysis.The content is structured into three parts. Part one introduces basic knowledge about popular bioinformatics tools, databases and web resources. Part two presents examples of omics bioinformatics applications. Part three provides basic statistical analysis skills and programming skills needed to handle and analyze omics datasets.
| Author | : Mourad Elloumi |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1027 |
| Release | : 2011-04-04 |
| Genre | : Science |
| ISBN | : 1118101987 |
This book represents the most comprehensive and up-to-date collection of information on the topic of computational molecular biology. Bringing the most recent research into the forefront of discussion, Algorithms in Computational Molecular Biology studies the most important and useful algorithms currently being used in the field, and provides related problems. It also succeeds where other titles have failed, in offering a wide range of information from the introductory fundamentals right up to the latest, most advanced levels of study.
| Author | : Yinglin Xia |
| Publisher | : Springer |
| Total Pages | : 518 |
| Release | : 2018-10-06 |
| Genre | : Computers |
| ISBN | : 9811315345 |
This unique book addresses the statistical modelling and analysis of microbiome data using cutting-edge R software. It includes real-world data from the authors’ research and from the public domain, and discusses the implementation of R for data analysis step by step. The data and R computer programs are publicly available, allowing readers to replicate the model development and data analysis presented in each chapter, so that these new methods can be readily applied in their own research. The book also discusses recent developments in statistical modelling and data analysis in microbiome research, as well as the latest advances in next-generation sequencing and big data in methodological development and applications. This timely book will greatly benefit all readers involved in microbiome, ecology and microarray data analyses, as well as other fields of research.
