Preparation Of Functionalized Oxazolines And Oxazoles
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Oxazoles, Volume 60, Part A
| Author | : David C. Palmer |
| Publisher | : Wiley-Interscience |
| Total Pages | : 0 |
| Release | : 2003-07-09 |
| Genre | : Science |
| ISBN | : 9780471394945 |
The Chemistry of Heterocyclic Compounds series attempts to make the extraordinarily complex and diverse field of heterocyclic chemistry as organized and readily accessible as possible, presenting a basic reference collection for practicing researchers. Volume 60, Oxazoles: Synthesis, Reactions, and Spectroscopy, Part A proves the sole comprehensive resource on the synthetic chemistry of oxazoles–heterocyclic compounds containing nitrogen and oxygen, specifically five-membered, unsaturated rings. Oxazoles have a wide variety of applications in synthetic organic chemistry and have been found in numerous natural products such as hennoxazole, thiangazole, calyculin, halicondrins, pyrenolide, virginiamycin, amphotericin, and phorboxazoles. This volume provides an authoritative review of the literature since 1983, highlights compounds of commerical importance, and includes in-depth coverage of the synthesis, reactions, and spectroscopic and physical properties for each class of compounds. It also discusses in detail the exciting developments on the use of chiral bioxazolines in asymmetric synthesis.
Heterocycles in Natural Product Synthesis
| Author | : Krishna C. Majumdar |
| Publisher | : John Wiley & Sons |
| Total Pages | : 648 |
| Release | : 2011-06-15 |
| Genre | : Science |
| ISBN | : 3527634894 |
Filling a gap on the market, this handbook and ready reference is unique in its discussion of the usefulness of various heterocyclic systems in the synthesis of natural products. Clearly structured for easy access to the information, each chapter is devoted to a certain class of heterocycle, providing a tabular presentation of the natural products to be covered containing the particular heterocyclic ring system along with their biological profile, occurrence and most important physical properties, backed by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products ic covered in detail. Of great interest to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry.
Synthetic Approaches to Nonaromatic Nitrogen Heterocycles
| Author | : Ana Maria Faisca Phillips |
| Publisher | : John Wiley & Sons |
| Total Pages | : 864 |
| Release | : 2020-11-18 |
| Genre | : Science |
| ISBN | : 1119708753 |
A comprehensive overview of synthetic strategies for nonaromatic nitrogen heterocycles Nitrogen heterocycles are extremely widely distributed in nature, as well as in synthetic substances found in pharmaceuticals, agrochemicals, and materials chemistry. With new structures and medicines that include these structures emerging yearly, and a vast new journal literature to describe them, anyone who wants to be effective in R&D needs to easily access a synthesis of the latest research. This state-of-the-art survey explores recent developments in the most widely used reactions, as well as completely new ones. Highlights the major modern synthetic methods known to obtain nonaromatic nitrogen heterocycles, and their practical applications Topics include enantioselective synthesis and catalysis, photocatalysis, biocatalysis, microwave-assisted synthesis, reactions of oximes and nitrones, and ionic liquids Discusses how to synthesize rings of specific sizes Covers sustainable synthetic approaches for obtaining salts Whether you are using nonaromatic nitrogen compounds as an academic researcher, a synthetic chemist in industry, or an advanced student, this book is an essential, up-to-date resource to support your work.
19th International Congress on Heterocyclic Chemistry
| Author | : Robert M. Williams |
| Publisher | : Newnes |
| Total Pages | : 423 |
| Release | : 2012-12-02 |
| Genre | : Science |
| ISBN | : 0080984010 |
This book presents the abstracts of the 19th International Congress of Heterocyclic Chemistry (19th ICHC) held in Fort Collins, Colorado, 10-15th August 2003 and provides the reader with a topical comprehensive reference source covering the latest developments in the heterocycles area. Each lecture from the 19th ICHC is presented as a one page abstract containing a textual summary of the lecture, including references, figures and contact details of the author(s).Papers are divided into the following sections: heterocyclic natural products, heterocycles in organic synthesis, bioactive heterocycles, heterocyclic materials &related topics, heterocyclic pharmaceuticals.The book of abstracts provides a topical reference source covering the latest developments in the heterocyles area.
Oxazole, Isoxazole, Benzoxazole-Based Drug Discovery
| Author | : Erum Akbar Hussain |
| Publisher | : Elsevier |
| Total Pages | : 304 |
| Release | : 2024-09-17 |
| Genre | : Science |
| ISBN | : 0323915698 |
Oxazole, Isoxazole, Benzoxazole Based Drug Discovery offers complete coverage of oxazole and related molecules, both from natural and synthetic origin, with a focus on the reaction mechanisms, and medicinal, pharmacokinetic and computational aspects. New and contemporary methods of synthesis are discussed, with a special focus on green, environment-friendly procedures. Discussion of stereochemical studies, particularly on natural molecules, are included. Computational chemistry has emerged as an integral tool for drug discovery, hence this book explains how the drug candidate is established as suitable for clinical trials with the help of molecular docking and virtual screening modeling. This book offers a broad range of recent developments and detailed coverage of synthesis and biological activities of the drugs, and is an ideal reference guide to researchers working in organic and medicinal chemistry. - Presents detailed coverage of chemical structures and practical synthetic methods of oxazoles, isoxazoles and benzoxazoles in drug discovery - Includes green, environmentally-friendly novel synthetic methods and mechanistic insights - Features biological and computational aspects of the oxazoles family of drugs, including virtual screening and molecular docking
Oxazoles, Volume 45
| Author | : I. J. Turchi |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1082 |
| Release | : 2009-09-15 |
| Genre | : Science |
| ISBN | : 0470188804 |
A reference that describes all of the important syntheses and reactions of oxazoles and oxazolones published through the first quarter of l984. Emphasizes the use of oxazoles as synthetic reagents as well as presenting the more classical treatments of oxazole chemistry. Contains the only extensive list of tables of oxazole derivatives and the most complete list of spectroscopic properties of oxazoles. Offers the most detailed treatment of mesoionic oxazoles including syntheses, specroscopy and reactions.
Isocyanide-based Multicomponent Reactions
| Author | : Jonathan G. Rudick |
| Publisher | : Frontiers Media SA |
| Total Pages | : 100 |
| Release | : 2020-02-20 |
| Genre | : |
| ISBN | : 2889634841 |
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Organic Syntheses Based on Name Reactions and Unnamed Reactions
| Author | : Alfred Hassner |
| Publisher | : Elsevier |
| Total Pages | : 462 |
| Release | : 2013-10-22 |
| Genre | : Science |
| ISBN | : 1483287343 |
Synthetically useful organic reactions or reagents are often referred to by the name of the discoverer(s) or developer(s). Older name reactions are described in text books, but more recently developed synthetically useful reactions that may have been associated occasionally with a name are not always well known. For neither of the above are experimental procedures or references easy to find. In this monograph approximately 500 name reactions are included, of which over 200 represent newer name reactions and modern reagents. Each of these reactions are extremely useful for the contemporary organic chemistry researcher in industry or academic institutions. This book provides the information in an easily accessible form. In addition to seminal references and reviews, one or more examples for each name reaction are provided and a complete typical experimental procedure is included, to enable the student or researcher to immediately evaluate reaction conditions. Besides an alphabetical listing of reactions and reagents, cross references permit the organic practitioner to find those name reactions or reagents that enable specific transformations, such as, conversion of amines to nitriles, stereoselective reduction, fluoroalkylation, phenol alkynylation, asymmetric syntheses, allylic alkylation, nucleoside synthesis, cyclopentanation, hydrozirconation, to name a few. Emphasis has been placed on stereoselective and regioselective transformations as well as on enantioselective processes. The listing of reactions and reagents is supported by four indexes.
Oxazoles, Volume 60, Part A
| Author | : David C. Palmer |
| Publisher | : John Wiley & Sons |
| Total Pages | : 662 |
| Release | : 2003-04-29 |
| Genre | : Science |
| ISBN | : 0471461458 |
The Chemistry of Heterocyclic Compounds series attempts to make the extraordinarily complex and diverse field of heterocyclic chemistry as organized and readily accessible as possible, presenting a basic reference collection for practicing researchers. Volume 60, Oxazoles: Synthesis, Reactions, and Spectroscopy, Part A proves the sole comprehensive resource on the synthetic chemistry of oxazoles–heterocyclic compounds containing nitrogen and oxygen, specifically five-membered, unsaturated rings. Oxazoles have a wide variety of applications in synthetic organic chemistry and have been found in numerous natural products such as hennoxazole, thiangazole, calyculin, halicondrins, pyrenolide, virginiamycin, amphotericin, and phorboxazoles. This volume provides an authoritative review of the literature since 1983, highlights compounds of commerical importance, and includes in-depth coverage of the synthesis, reactions, and spectroscopic and physical properties for each class of compounds. It also discusses in detail the exciting developments on the use of chiral bioxazolines in asymmetric synthesis.
