Bringing thinking from the arts and digital humanities into dialogue with one another, this book investigates what it means to be alive in a world that is structured by technology, the media, and an ever expanding sense of a global community. In this unique time in our history, when we are bombarded by signs and symbols and constantly connected into gadgets, apps, and networks, it has become increasingly difficult to navigate what has been dubbed a 'post-truth' world. Critiques taken from post-colonial studies and neoanimism help challenge the paranoia that has become endemic and, indeed, symptomatic to global realities we are now witnessing. This pertains not only to the ecological degradation of the planet but also to the lingering remnants of eurocentrism and racism that have taken the forms of nationalism and fascism. As a guide, an updated version of what Michel Foucault called an arts of existence may help us sail in these treacherous and confusing waters. Diving into post-structuralist French theory, through American feminism, and emerging out of media studies, this book argues for an ethical and aesthetic form of self-fashioning that runs counter to processes subjection and mediatization. This craft of life, as Plato called it, is a space of disjunction and liberation, between subjectivity and other, where something new and different has the potential to emerge and mould to our likeness.