Pharmaceutical Organic Chemistry -E-Book

Pharmaceutical Organic Chemistry -E-Book
Author: S.K. Bhasin
Publisher: Elsevier Health Sciences
Total Pages: 819
Release: 2012-04-01
Genre: Medical
ISBN: 8131232670

Pharmaceutical Organic Chemistry has been written keeping in mind the severe need for a comprehensive text to meet the curriculum needs of the undergraduate pharmacy students. It not only provides all the curriculum topics to the students but also contains all the vital reactions/mechanisms that the students look for in an organic chemistry book. - Entire subject matter has been written in a systematic and lucid style in simple language. - All the basic concepts and fundamentals of organic chemistry have been explained with well-chosen examples. - For better understanding of the subject matter, important points have been highlighted in the form of the textboxes titled as Remember, Learning Plus and Noteworthy Points, wherever required. - Summary of the topics in the form of Memory Focus has been given at relevant places to help the students to revise the subject matter quickly. - Stepwise mechanism of the reactions as per the syllabus has been illustrated, laying emphasis on the reactive intermediates involved. - At the end of each chapter, Revision Questions including descriptive questions and short answer questions have been given for the students to practice. Multiple Choice Questions with answers have been included at the end of each chapter.

Pharmaceutical Organic Chemistry

Pharmaceutical Organic Chemistry
Author: V. Alagarsamy
Publisher: BSP Books
Total Pages: 1350
Release: 2020-06-20
Genre: Science
ISBN: 9389354781

Pharmaceutical organic chemistry is the main branch of organic chemistry deals with the study of preparation, structure and reactions of organic compounds. As it deals with all the chemical reactions related to life, study of Pharmaceutical organic chemistry is important. Application of Organic chemistry in the development of pharmaceuticals, resulted in evolving Pharmaceutical organic chemistry. Hence studying Organic chemistry and applying this knowledge in Pharmaceutical substances is called as Pharmaceutical organic chemistry. Organic chemistry forms the basis of biochemistry, in which various aspects of health and diseases are studied. The biochemical knowledge is very important for the practice of nutritional, medical and related life sciences. In addition Organic chemistry paved way for the development of medicinal chemistry, Pharmaceutical organic chemistry, bioinformatics, biotechnology, gene therapy, Pharmacology, pathology, chemical engineering, dental science and so on. Organic substances play such a vital role in our daily life that all of us should know about organic chemistry in order to understand the manner how it influence our life process.

Essentials of Organic Chemistry

Essentials of Organic Chemistry
Author: Paul M. Dewick
Publisher: John Wiley & Sons
Total Pages: 711
Release: 2013-03-20
Genre: Science
ISBN: 1118681967

Essentials of Organic Chemistry is an accessible introduction to the subject for students of Pharmacy, Medicinal Chemistry and Biological Chemistry. Designed to provide a thorough grounding in fundamental chemical principles, the book focuses on key elements of organic chemistry and carefully chosen material is illustrated with the extensive use of pharmaceutical and biochemical examples. In order to establish links and similarities the book places prominence on principles and deductive reasoning with cross-referencing. This informal text also places the main emphasis on understanding and predicting reactivity rather than synthetic methodology as well as utilising a mechanism based layout and featuring annotated schemes to reduce the need for textual explanations. * tailored specifically to the needs of students of Pharmacy Medical Chemistry and Biological Chemistry * numerous pharmaceutical and biochemical examples * mechanism based layout * focus on principles and deductive reasoning This will be an invaluable reference for students of Pharmacy Medicinal and Biological Chemistry.

Organic Chemistry of Drug Degradation

Organic Chemistry of Drug Degradation
Author: Min Li
Publisher: Royal Society of Chemistry
Total Pages: 311
Release: 2015-10-20
Genre: Medical
ISBN: 1782625631

The vast majority of drugs are organic molecular entities. A clear understanding of the organic chemistry of drug degradation is essential to maintaining the stability, efficacy, and safety of a drug product throughout its shelf-life. During analytical method development, stability testing, and pharmaceutical manufacturing troubleshooting activities, one of the frequently occurring and usually challenging events would be the identification of drug degradants and understanding of drug degradation mechanisms and pathways. This book is written by a veteran of the pharmaceutical industry who has first-hand experience in drug design and development, drug degradation mechanism studies, analytical development, and manufacturing process troubleshooting and improvement. The author discusses various degradation pathways with an emphasis on the mechanisms of the underlying organic chemistry, which should aid greatly in the efforts of degradant identification, formulation development, analytical development, and manufacturing process improvement. Organic reactions that are significant in drug degradation will first be reviewed and then illustrated by examples of drug degradation reported in the literature. The author brings the book to a close with a final chapter dedicated to the strategy for rapid elucidation of drug degradants with regard to the current regulatory requirements and guidelines. One chapter that should be given special attention is Chapter 3, Oxidative Degradation. Oxidative degradation is one of the most common degradation pathways but perhaps the most complex one. This chapter employs more than sixty drug degradation case studies with in-depth discussion in regard to their unique degradation pathways. With the increasing regulatory requirements on the quality and safety of pharmaceutical products, in particular with regard to drug impurities and degradants, the book will be an invaluable resource for pharmaceutical and analytical scientists who engage in formulation development, analytical development, stability studies, degradant identification, and support of manufacturing process improvement. In addition, it will also be helpful to scientists engaged in drug discovery and development as well as in drug metabolism studies.

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action
Author: Richard B. Silverman
Publisher: Elsevier
Total Pages: 650
Release: 2012-12-02
Genre: Science
ISBN: 0080513379

Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

Pharmaceutical Organic Chemistry-Iii

Pharmaceutical Organic Chemistry-Iii
Author: Pramod Nayanapalli
Publisher: Educreation Publishing
Total Pages: 124
Release: 2019-02-20
Genre: Education
ISBN:

PREFACE The main objective of writing this book for II B.Pharmacy, IV semester is to gain knowledge about stereochemical considerations are important in both isomerism. the relative three-dimensional orientation of the reacting particles at any time in the reaction. Concentrating on organic chemistry, early chapters deal mainly with definitions of terms such as chirality, enantiomers, diastereoisomers, meso type and racemization, complete with suitable examples to illustrate key concepts. Use of a polarimeter and associated definitions are described, together with two different conventions D, L and R, S and E, Z. Aspects of stereochemistry are explored through consideration of addition reactions to alkenes and carbonyl groups, nucleophilic substitution, and reactions (and interactions) involved in the resolution of racemic mixtures. The book also provide knowledge related to heterocyclic compounds their nomenclature preparations reactions basicity and aromaticity including applications of every heterocyclic nucleus that are mentioned according PCI syllabus were discussed. Some of the synthetic important named reactions and mechanism presented simple way for the easy understanding for students. Over this entire book help students to learn subject concept orient, to express well during respective university examination and get through examination successfully.

Pharmaceutical Organic Chemistry

Pharmaceutical Organic Chemistry
Author: S C Shetty
Publisher:
Total Pages: 270
Release: 2016-05-16
Genre: Fiction
ISBN: 9789351647959

Semester III 1 Stereochemistry 2 Molecular rearrangement reactions 3 Chemistry of amino acids and proteins 4 Pollcyclic compounds Semester IV 1 Heterocyclic compounds 2 Introduction to combinatorial chemistry 3 Retro synthesis 4 Chemistry of carbohydrates 5 Nanochemistry and microwave assisted synthesis

PHARMACEUTICAL ORGANIC CHEMISTRY –I

PHARMACEUTICAL ORGANIC CHEMISTRY –I
Author: Mr. Shaikh Parvej Harunrashid
Publisher: JEC PUBLICATION
Total Pages: 244
Release:
Genre: Medical
ISBN: 9361754823

The study of Pharmaceutical Organic Chemistry is a cornerstone of the pharmaceutical sciences, providing a critical understanding of the chemical foundations that underpin drug design, synthesis, and action. This textbook, "Pharmaceutical Organic Chemistry – I," is designed to serve as an introductory guide for students, educators, and professionals who are beginning their journey into this fascinating field. The content of this book is meticulously structured to provide a comprehensive yet accessible exploration of the fundamental concepts of organic chemistry as they relate to pharmaceuticals. Starting with the basics of chemical reactions, molecular structure, and functional groups, the text gradually progresses to more complex topics such as reaction mechanisms, stereochemistry, and the synthesis of various organic compounds used in the pharmaceutical industry. The aim is to build a solid foundation that will support further study and application in the field. In crafting this book, special attention has been given to aligning the material with the needs of students. Each chapter is designed to not only impart theoretical knowledge but also to encourage practical understanding through examples, exercises, and real-world applications. The integration of qualitative tests, structure elucidation, and discussions on the uses of specific compounds provides a holistic view that bridges the gap between theory and practice. The importance of this subject in the broader context of pharmaceutical sciences cannot be overstated. A deep understanding of organic chemistry is essential for anyone involved in the development of new drugs, the improvement of existing therapies, or the advancement of medicinal chemistry. By mastering the concepts presented in this book, students will be wellequipped to tackle the challenges of drug discovery and development. WE hope that this book will serve as a valuable resource for those studying Pharmaceutical Organic Chemistry, helping them to gain the knowledge and confidence needed to excel in their academic and professional endeavors. It is my sincere hope that the readers find this text not only informative but also inspiring, as they embark on their journey to contribute to the vital field of pharmaceutical sciences. We extend our best wishes to all the readers and students who will use this book as a tool to further their understanding of organic chemistry and its applications in the pharmaceutical world. May it serve as a stepping stone toward greater achievements in your academic and professional careers.