Perspectives on Research with H5N1 Avian Influenza

Perspectives on Research with H5N1 Avian Influenza
Author: National Research Council
Publisher: National Academies Press
Total Pages: 133
Release: 2013-04-04
Genre: Medical
ISBN: 0309267781

When, in late 2011, it became public knowledge that two research groups had submitted for publication manuscripts that reported on their work on mammalian transmissibility of a lethal H5N1 avian influenza strain, the information caused an international debate about the appropriateness and communication of the researchers' work, the risks associated with the work, partial or complete censorship of scientific publications, and dual-use research of concern in general. Recognizing that the H5N1 research is only the most recent scientific activity subject to widespread attention due to safety and security concerns, on May 1, 2012, the National Research Council's Committee on Science, Technology and Law, in conjunction with the Board on Life Sciences and the Institute of Medicine's Forum on Microbial Threats, convened a one-day public workshop for the purposes of 1) discussing the H5N1 controversy; 2) considering responses by the National Institute of Allergy and Infectious Diseases (NIAID), which had funded this research, the World Health Organization, the U.S. National Science Advisory Board for Biosecurity (NSABB), scientific publishers, and members of the international research community; and 3) providing a forum wherein the concerns and interests of the broader community of stakeholders, including policy makers, biosafety and biosecurity experts, non-governmental organizations, international organizations, and the general public might be articulated. Perspectives on Research with H5N1 Avian Influenza: Scientific Enquiry, Communication, Controversy summarizes the proceedings of the workshop.

Bird Flu

Bird Flu
Author: Michael Greger
Publisher: Lantern Books
Total Pages: 0
Release: 2006
Genre: Avian influenza
ISBN: 1590560981

The author explores the underlying conditions that would create a bird flu pandemic, examines the ways in which the public can protect themselves and their families, and describes what can be done to reduce the likelihood of spreading this disease.

Avian Reservoirs

Avian Reservoirs
Author: Frédéric Keck
Publisher: Duke University Press
Total Pages: 167
Release: 2020-01-17
Genre: Social Science
ISBN: 1478007559

After experiencing the SARS outbreak in 2003, Hong Kong, Singapore, and Taiwan all invested in various techniques to mitigate future pandemics involving myriad cross-species interactions between humans and birds. In some locations microbiologists allied with veterinarians and birdwatchers to follow the mutations of flu viruses in birds and humans and create preparedness strategies, while in others, public health officials worked toward preventing pandemics by killing thousands of birds. In Avian Reservoirs Frédéric Keck offers a comparative analysis of these responses, tracing how the anticipation of bird flu pandemics has changed relations between birds and humans in China. Drawing on anthropological theory and ethnographic fieldwork, Keck demonstrates that varied strategies dealing with the threat of pandemics—stockpiling vaccines and samples in Taiwan, simulating pandemics in Singapore, and monitoring viruses and disease vectors in Hong Kong—reflect local geopolitical relations to mainland China. In outlining how interactions among pathogens, birds, and humans shape the way people imagine future pandemics, Keck illuminates how interspecies relations are crucial for protecting against such threats.

Wild Birds and Avian Influenza

Wild Birds and Avian Influenza
Author: Darrell Whitworth
Publisher: Food & Agriculture Org.
Total Pages: 124
Release: 2007
Genre: Medical
ISBN: 9789251059081

The highly pathogenic avian influenza H5N1 strain has spread from domestic poultry to a large number of species of free-ranging wild birds, including non-migratory birds and migratory birds that can travel thousands of kilometers each year. The regular contact and interaction between poultry and wild birds has increased the urgency of understanding wild bird diseases and the transmission mechanisms that exist between the poultry and wild bird sectors, with a particular emphasis on avian influenza. Monitoring techniques, surveillance, habitat use and migration patterns are all important aspects of wildlife and disease ecology that need to be better understood to gain insights into disease transmission between these sectors. This manual contains chapters on the basic ecology of avian influenza and wild birds, capture and marking techniques (ringing, color marking and satellite telemetry), disease sampling procedures, and field survey and monitoring procedures.--Publisher's description.

Potential Risks and Benefits of Gain-of-Function Research

Potential Risks and Benefits of Gain-of-Function Research
Author: National Research Council
Publisher: National Academies Press
Total Pages: 131
Release: 2015-04-13
Genre: Science
ISBN: 0309367867

On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting.

130 Years of Medicine in Hong Kong

130 Years of Medicine in Hong Kong
Author: Frank Ching
Publisher: Springer
Total Pages: 526
Release: 2018-03-14
Genre: Medical
ISBN: 9811063168

This book reviews the medical history of Hong Kong, beginning with its birth as a British colony. It introduces the origins of Hong Kong’s medical education, which began in 1887 when the London Missionary Society set up the Hong Kong College of Medicine for Chinese. When the University of Hong Kong was established in 1911, the College became its medical faculty. The faculty has gained distinction over the years for innovative surgical techniques, for discovering the SARS virus and for its contribution to advances in medical and health sciences. This book is meant for general readers as well as medical practitioners. It is a work for anyone interested in Hong Kong or in medical education.

Critical Needs for Research in Veterinary Science

Critical Needs for Research in Veterinary Science
Author: National Research Council
Publisher: National Academies Press
Total Pages: 238
Release: 2005-10-18
Genre: Technology & Engineering
ISBN: 0309164982

Research in veterinary science is critical for the health and well-being of animals, including humans. Food safety, emerging infectious diseases, the development of new therapies, and the possibility of bioterrorism are examples of issues addressed by veterinary science that have an impact on both human and animal health. However, there is a lack of scientists engaged in veterinary research. Too few veterinarians pursue research careers, and there is a shortage of facilities and funding for conducting research. This report identifies questions and issues that veterinary research can help to address, and discusses the scientific expertise and infrastructure needed to meet the most critical research needs. The report finds that there is an urgent need to provide adequate resources for investigators, training programs, and facilities involved in veterinary research.

Epidemiology of Avian Influenza Viruses

Epidemiology of Avian Influenza Viruses
Author: Irene Iglesias
Publisher: Frontiers Media SA
Total Pages: 133
Release: 2019-08-29
Genre:
ISBN: 2889459942

Avian influenza is a highly contagious viral disease, characterized by intense circulation in the wild waterbird reservoirs, with periodical introductions into the domestic poultry sector. AI viruses have been the source of devastating economic losses in the poultry industry over the last three decades, and have become a major veterinary and public health concern due to their zoonotic potential. The most emblematic illustration of this impact has been the emergence of the HPAI H5N1 virus in southern China in the mid-1990s, followed by its continental spread across East and Southeast Asia, and the unprecedented epidemics recorded in 2003–2004. More recently (from 2014 to 2017), several subtypes of HPAI (including H5N1, H5N6, H5N8) emerged in East Asia and spread intercontinentally, stressing the crucial role of this geographical hotspot as a source of new HPAI subtypes. The international dimension and the difficulty to effectively control those epidemics highlight the need for a global approach to HPAI surveillance and a comprehensive knowledge on epidemiology and patterns of the disease. This Research Topic aims at contributing to fill this gap. It includes ten papers which supplement the knowledge of the epidemiology of AI and offer new approaches on control strategies in various regions of the world.

The Threat of Pandemic Influenza

The Threat of Pandemic Influenza
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 431
Release: 2005-04-09
Genre: Medical
ISBN: 0309095042

Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns. The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.