Peptide Synthesis and Applications

Peptide Synthesis and Applications
Author: Knud J. Jensen
Publisher: Humana
Total Pages: 0
Release: 2016-08-27
Genre: Science
ISBN: 9781493960040

Peptides are used ubiquitously for studies in biology, biochemistry, chemical biology, peptide based medicinal chemistry, and many other areas of research. There is a number of marketed peptide drugs, and the prospects for the development of new peptide drugs are very encouraging. The second edition of Peptide Synthesis and Applications expands upon the previous editions with current, detailed methodologies for peptide synthesis. With new chapters on laboratory protocols for both the specialist and the non-specialist. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Peptide Synthesis and Application, Second Edition seeks to aid scientists in understanding different approaches to the synthesis of peptides by using a broad range of methods and strategies.

Peptide Applications in Biomedicine, Biotechnology and Bioengineering

Peptide Applications in Biomedicine, Biotechnology and Bioengineering
Author: Sotirios Koutsopoulos
Publisher: Woodhead Publishing
Total Pages: 655
Release: 2017-11-16
Genre: Technology & Engineering
ISBN: 0081007426

Peptide Applications in Biomedicine, Biotechnology and Bioengineering summarizes the current knowledge on peptide applications in biomedicine, biotechnology and bioengineering. After a general introduction to peptides, the book addresses the many applications of peptides in biomedicine and medical technology. Next, the text focuses on peptide applications in biotechnology and bioengineering and reviews of peptide applications in nanotechnology. This book is a valuable resource for biomaterial scientists, polymer scientists, bioengineers, mechanical engineers, synthetic chemists, medical doctors and biologists. - Presents a self-contained work for the field of biomedical peptides - Summarizes the current knowledge on peptides in biomedicine, biotechnology and bioengineering - Covers current and potential applications of biomedical peptides

Peptide Synthesis and Applications

Peptide Synthesis and Applications
Author: John Howl
Publisher: Springer Science & Business Media
Total Pages: 263
Release: 2008-02-02
Genre: Science
ISBN: 1592598773

Hands-on experts describe in step-by-step detail the key methodologies of contemporary peptide synthesis and illustrate their numerous applications. The techniques presented include protocols for chemical ligation, the synthesis of cyclic and phosphotyrosine-containing peptides, lipoamino acid- and sugar-conjugated peptides, and peptide purification and analyses. Additional chapters detail methodologies and instrumentation for high-throughput peptide synthesis, many different applications of peptides as novel research tools and biological probes, and the design and application of fluorescent substrate-based peptides that can be used to determine the selectivity and activity of peptidases. A practical guide to the identification of proteins using mass spectrometric analyses of peptide mixtures is also included.

Peptides

Peptides
Author: Bernd Gutte
Publisher: Elsevier
Total Pages: 527
Release: 1995-10-24
Genre: Science
ISBN: 0080538592

In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries. In this comprehensive book, the authors discuss peptide synthesis and application within the context of their increasing importance to the pharmaceutical industry. Peptides: Synthesis, Structures, and Applications explores the broad growth of information in modern peptide synthetic methods and the structure-activity relationships of synthetic polypeptides. - The history of peptide chemistry - Amide formation, deprotection, and disulfide formation in peptide synthesis - Solid-phase peptide synthesis - a-helix formation by peptides in water - Stability and dynamics of peptide conformation - An overview of structure-function studies of peptide hormones - Neuropeptides:peptide and nonpeptide analogs - Reversible inhibitors of serine proteinases - Design of polypeptides - Current capabilities and future possibilities of soluble chemical combinatorial libraries - Epitope mapping with peptides - Synthesis and applications of branched peptides in immunological methods and vaccines

Solid-Phase Peptide Synthesis

Solid-Phase Peptide Synthesis
Author: Gregg B. Fields
Publisher: Academic Press
Total Pages: 828
Release: 1997-10-21
Genre: Medical
ISBN:

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volumehas been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 275 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchers in all fields of life sciences. Key Features * Solid-phase peptide synthesis * Applications of peptides for structural and biological studies * Characterization of synthetic peptides

Cyclic Peptides

Cyclic Peptides
Author: Jesko Koehnke
Publisher: Royal Society of Chemistry
Total Pages: 392
Release: 2017-12-15
Genre: Science
ISBN: 1782625283

This book provides the reader with a comprehensive view of the state-of-the-art of cyclic peptides, from construction to utility in biology and drug discovery.

Chemical Approaches to the Synthesis of Peptides and Proteins

Chemical Approaches to the Synthesis of Peptides and Proteins
Author: Paul Lloyd-Williams
Publisher: CRC Press
Total Pages: 306
Release: 1997-04-23
Genre: Medical
ISBN: 9780849391422

Organic chemists working on the synthesis of natural products have long found a special challenge in the preparation of peptides and proteins. However, more reliable, more efficient synthetic preparation methods have been developed in recent years. This reference evaluates the most important synthesis methods available today, and also considers methods that show promise for future applications. This text describes the state of the art in efficient synthetic methods for the synthesis of both natural and artificial large peptide and protein molecules. Subjects include an introduction to basic topics, linear solid-phase synthesis of peptides, peptide synthesis in solution, convergent solid-phase synthesis, methods for the synthesis of branched peptides, formation of disulfide bridges, and more. The book emphasizes strategies and tactics that must be considered for the successful synthesis of peptides.

Fmoc Solid Phase Peptide Synthesis

Fmoc Solid Phase Peptide Synthesis
Author: W. Chan
Publisher: OUP Oxford
Total Pages: 371
Release: 1999-12-16
Genre: Science
ISBN: 0199637245

Since the publication of Atherton and Sheppard's volume, the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. The focus of this new volume is much broader, and covers the essential procedures.

Peptide Synthesis

Peptide Synthesis
Author: Jaya Varkey
Publisher: BoD – Books on Demand
Total Pages: 120
Release: 2019-12-18
Genre: Science
ISBN: 1839682574

Peptide synthesis includes an array of techniques and procedures that enable the preparation of materials ranging from small peptides to large proteins. Many synthetic peptides have commercial and pharmaceutical applications, however, the synthesis of these peptides is a difficult task. This book addresses the common problems relating to the synthesis and applications of synthetic peptides. It discusses novel methods for the efficient synthesis of long chain and difficult peptide sequences and presents detailed analysis of various aspects of solid phase peptide synthesis. It also includes a section on antimicrobial peptides.

Chemistry of Peptide Synthesis

Chemistry of Peptide Synthesis
Author: N. Leo Benoiton
Publisher: CRC Press
Total Pages: 304
Release: 2016-04-19
Genre: Medical
ISBN: 1420027697

Chemistry of Peptide Synthesis is a complete overview of how peptides are synthesized and what techniques are likely to generate the most desirable reactions. Incorporating elements from the author's role of Career Investigator of the Medical Research Council of Canada and his extensive teaching career, the book emphasizes learning rather th