Dioxins and Health

Dioxins and Health
Author: A. Schecter
Publisher: Springer Science & Business Media
Total Pages: 740
Release: 1994-12-31
Genre: Science
ISBN: 9780306447853

This book originated in a series of cross-disciplinary conversations in the years 1984-1990 between the editor, who is a physician-researcher involved in clinical and laboratory research, and a dioxin toxicologist. During the years in which the conversations took place, an extraordinary amount of new scientific literature was published related to dioxins, defined for purposes of this text as the chlorinated dibenzo-p-dioxins, dibenzofurans, polychlorinated biphe nyls (PCB's) and other compounds that are structurally and toxicologically similar to 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7 ,8-TCDD), the most extensively studied and most toxic of this group of chemicals. Dioxins also began to interest not only chemists and toxicologists, but also specialists from diverse disciplines such as wildlife and environmental science, immunology, neuroscience,public health, epidemiology, med icine, government, law, sociology, and journalism. Specialists from such varied disciplines, while familiar with their own literature, frequently did not have time to follow the dioxin literature outside their specialty area. In addition, each specialty had unique knowledge, methods, and perspectives. Cross disciplinary conversation was necessary, but all too frequently, specialists from the various disciplines did not speak the same language, resulting in misunderstanding.

Chemical Contaminants in Human Milk

Chemical Contaminants in Human Milk
Author: Allan Astrup Jensen
Publisher: CRC Press
Total Pages: 318
Release: 1990-11-20
Genre: Medical
ISBN: 9780849366079

Chemical Contaminants in Human Milk contains a comprehensive, up-to-date global review of the contamination of human milk with environmental and occupational chemicals. The book covers many different aspects of this problem, including the extent and benefits of breast-feeding, the transfer of chemicals into breast milk, analytical methodologies used in human milk studies, the levels of chemical contaminants in human milk, and geographical variations and time trends in levels. The many different factors that can influence the levels of contaminants in breast milk are also discussed. Other important topics examined include human milk contamination due to exposure of the mother at the workplace and the risk to her baby, the intake of toxic chemicals by breast-fed infants, calculated intakes and official limit values, the toxicological implications of human milk contamination based on available data from animal experiments and human studies. The book concludes with an overall assessment of the current situation, together with recommendations for future work. Chemical Contaminants in Human Milk is a valuable source of information for pediatricians and other health professionals, policy makers involved with ensuring the health and welfare of infants and nursing mothers, nursing mothers and organizations involved in the promotion of breast feeding, and individuals and organizations involved with the study and control of environmental pollution and occupational hygiene.

Polychlorinated Biphenyls (PCBs): Mammalian and Environmental Toxicology

Polychlorinated Biphenyls (PCBs): Mammalian and Environmental Toxicology
Author: Stephen Safe
Publisher: Springer Science & Business Media
Total Pages: 244
Release: 2012-12-06
Genre: Technology & Engineering
ISBN: 3642705502

Polychlorinated biphenyls (PCBs) have been produced commercially since be fore 1930. They proved to be highly versatile mixtures and their uses continued to expand during the early 1970's even after the unanticipated world-wide en vironmental contamination had been discovered (Jensen et aI. , 1969; Koeman et aI. , 1969). Over 600,000 metric-tons were produced and/or used in the U. S. during this time and it is estimated that worldwide production totaled about 1,200,000 metric-tons (Table 1). With low acute toxicities (Fishbein, 1974), these mixtures were considered gen erally biologically inactive even though industrial exposure had demonstrated he patic and dermatological effects (Fishbein, 1974; Hansen, 1987). Thus, use and disposal were not carefully monitored and it is estimated that one-third of the world-wide production of PCBs has been released into the global environment (Table 1). Table 1. Estimated production and disposition of PCBs b U. s. a Worldwide 6 6 Production/use 610 X 10 kg 1200 X 10 kg Mobil environmental reservoir 82 400 Static reservoirs In service 340 Dumps 130 Total static 470 800 a NAS, 1979 b Tatsukawa and Tanaba, 1984 2 Environmental Distribution Many countries now impose strict controls on the use and release of PCBs. Re lease into the environment has declined dramatically in the last decade, but con tinued release from reservoirs (Table 1) into burdened ecosystems (Table 2) ap pears inevitable for several more decades (Barros et aI. , 1984).

Environmental and Chemical Toxins and Psychiatric Illness

Environmental and Chemical Toxins and Psychiatric Illness
Author: James S. Brown
Publisher: American Psychiatric Pub
Total Pages: 325
Release: 2008-08-13
Genre: Medical
ISBN: 1585627623

During the past 60 years, the number of chemical disasters worldwide from military, occupational, and environmental sources has risen at an alarming rate. The profound controversy surrounding many chemicals makes objective analysis nearly impossible. Yet now more than ever -- with the daily exposure to a wide range of chemicals and the increased threat of chemical terrorism -- it is critical that we understand the role of chemicals in causing psychiatric illness. Unlike related books, this remarkable reference is intended specifically for psychiatric applications and is thus the definitive sourcebook for the many professionals called on to respond to these events. This work stands alone as the first on this topic to be written by a psychiatrist and the first to bring together the military, occupational, and environmental exposures causing psychiatric illness, including multiple chemical sensitivities, mass hysteria, radiation exposures, community stress reactions, and Gulf War and other syndromes. Unique highlights include A summary of the reported psychiatric symptoms attributed to each chemical class (chemical weapons, pesticides, fumigants, metals, solvents, gases, PCBs, Agent Orange, and other miscellaneous chemicals) in tables for easy reference. We use personal care products, take prescription drugs, pump gasoline, drink alcohol, and spray insecticides as part of our everyday lives. Yet rarely do we realize that significant exposures to the chemicals described in this book -- many of which we are exposed to in daily activities -- can damage the central nervous system, causing psychiatric illness. A comprehensive bibliography, in every chapter, of all the important material in English-language medical journals and books that has appeared on this subject since the late 19th century. These bibliographies cover everything from the first published reports of the dangers of carbon disulfide in the French rubber industry -- dangers that American medicine ignored for years -- through more recent large-scale chemical exposures that have serious long-term consequences. (e.g., Love Canal). The latest information about terrorist and military uses of chemical weapons -- of critical relevance in psychiatry today -- from World War I combatants exposed to chlorine, phosgene, mustard gas, arsenic, and cyanide to the first organophosphate, or nerve, gases (such as tabun and sarin) developed by the Germans before and during World War II (and used by Iraq in the Gulf War and by a religious cult in the terrorist subway attacks in Tokyo and Matsumoto, Japan). Quite simply, this book is a "must have" for psychiatric and medical professionals everywhere, with extended appeal among laypersons such as environmental/consumer advocates, attorneys, insurance professionals, industrial hygienists, disaster planners, and medical librarians.

Hazards, Decontamination, and Replacement of PCB

Hazards, Decontamination, and Replacement of PCB
Author: Jean-Pierre Crine
Publisher: Springer Science & Business Media
Total Pages: 228
Release: 2012-12-06
Genre: Science
ISBN: 1461307473

Poly Chlorinated Biphenyls (PCBs) are dielectric liquids which have been widely used in various industries for more than 50 years because of their supposed nonflammabi 1 i ty and thei r chemical inertness. Recent acc idents all over the world have shown PCBs can burn and their combustion by products (dioxines, furanes, etc.) are highly toxic. In fact, confusion has been created in the pub 1 ie mind between the dangers and hazards induced by PCBs themselves and those generated by their byproducts. Meanwhile, PCB pollution and toxicity is a major concern for regulating agencies, such as EPA in the United States and industry. Most Western countries now ban PCB production and strictly control their use. However, enormous amounts of PCB remain in use and their safe handling, destruction and replacement are heavy burdens for industrial users. PCB pollution and its side effects are the subject of various studies with recent conferences devoted to these PCB studies. Thus a large body of specialized information now exists on the environmental, medical, bio logical and safety aspects of PCB handling, use, cleaning and decontami nation. However, no single comprehensive publication is yet available which deals with all the problems associated with PCBs. The major objective of the present book is to provide such a guide for PCB users. One interest of this book is that it brings together the point of view of scientists from widely different backgrounds: biologists, physicians, environmentalists, toxicologists, chemists, electrical engineers, etc.

America's Children and the Environment

America's Children and the Environment
Author: U.s. Environmental Protection Agency
Publisher: Createspace Independent Publishing Platform
Total Pages: 502
Release: 2017-05-31
Genre:
ISBN: 9781547052585

"America's Children and the Environment (ACE)" is EPA's report presenting data on children's environmental health. ACE brings together information from a variety of sources to provide national indicators in the following areas: Environments and Contaminants, Biomonitoring, and Health. Environments and Contaminants indicators describe conditions in the environment, such as levels of air pollution. Biomonitoring indicators include contaminants measured in the bodies of children and women of child-bearing age, such as children's blood lead levels. Health indicators report the rates at which selected health outcomes occur among U.S. children, such as the annual percentage of children who currently have asthma. Accompanying each indicator is text discussing the relevance of the issue to children's environmental health and describing the data used in preparing the indicator. Wherever possible, the indicators are based on data sources that are updated in a consistent manner, so that indicator values may be compared over time.

Patty's Toxicology, 6 Volume Set

Patty's Toxicology, 6 Volume Set
Author: Eula Bingham
Publisher: John Wiley & Sons
Total Pages: 5872
Release: 2012-07-31
Genre: Science
ISBN: 0470410817

Featuring the improved format used in the 5th edition, this updated set presents, in logical groupings, comprehensive toxicological data for industrial compounds, including CAS numbers, physical and chemical properties, exposure limits, and biological tolerance values for occupational exposures, making it essential for toxicologists and industrial hygienists. This edition has about 40% new authors who have brought a new and international perspective to interpreting industrial toxicology, and discusses new subjects such as nanotechnology, flavorings and the food industry, reactive chemical control to comprehensive chemical policy, metalworking fluids, and pharmaceuticals.

Toxic Risks

Toxic Risks
Author: Ronald E. Gots
Publisher: CRC Press
Total Pages: 294
Release: 1992-10-29
Genre: Science
ISBN: 9780873715102

Policymakers, health professionals, and the general public face growing concerns about environmental matters, particularly those related to "toxic" chemicals and their effects on public health. Toxic Risks: Science, Regulation, and Perception explores the political, popular, and regulatory aspects of toxicity and contrasts them with scientifically established facts. The book will be valuable for industrial hygienists, toxicologists, environmental scientists, occupational medicine physicians, family physicians, environmental consultants, government policymakers, and individuals interested in the effects of toxic chemicals on public health.