Pathophysiology Of Reperfusion Injury
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| Author | : Naseer Ahmed |
| Publisher | : Academic Press |
| Total Pages | : 0 |
| Release | : 2019-05-31 |
| Genre | : Science |
| ISBN | : 9780128180235 |
Pathophysiology of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is a deep examination into the mechanisms of myocardial ischemiareperfusion injury and role of fingolimod as a cardioprotective agent through its antioxidant, anti-apoptotic and anti-inflammatory effects. Dr. Ahmed explore the physiology and pathophysiology of myocardial metabolism under normal and ischemic conditions and focused on pharmacological cardioprotection. They provide a concise, yet rigorous discussion of Ischemia-Reperfusion Injury, Myocardial Ischemia during Circulatory Arrest, Myocardial Reperfusion, Myocardial Protection related to Ischemia-Reperfusion Injury and Role of Fingolimod in Cardioprotection. Pathophysiology of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is ideal for researchers, cardiovascular scientists, and clinical pharmacologists to further work in this challenging area and apply this knowledge to clinical trials for cardioprotection.
| Author | : Robert Fitridge |
| Publisher | : University of Adelaide Press |
| Total Pages | : 589 |
| Release | : 2011 |
| Genre | : Medical |
| ISBN | : 1922064009 |
New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
| Author | : Robert Fitridge |
| Publisher | : Springer Nature |
| Total Pages | : 739 |
| Release | : 2020-07-30 |
| Genre | : Medical |
| ISBN | : 3030436837 |
This extensively revised third edition provides a practically applicable guide to the pathophysiology, assessment and management of vascular disorders encountered in vascular surgical practice. It features detailed information on the latest developments in the pathophysiology of conditions including atherosclerosis, multi-organ failure, limb compartment syndromes and Raynaud’s phenomenon in a clear easy to digest format. Disorders such as reperfusion injuries, vasculitides, and aortic dissection are covered. Furthermore, key topics in vascular and endovascular practice such as radiation biology and radiation safety are also detailed. Each chapter contains a set of learning objectives and key references, enabling the reader to quickly identify key points. Mechanisms of Vascular Disease: A Textbook for Vascular Specialists comprehensively covers a variety of common and unusual pathophysiologies encountered in vascular surgery, and is an ideal resource for both the trainee, and practicing clinical vascular surgeon seeking an up-to-date resource on the topic.
| Author | : Cyril Mauffrey |
| Publisher | : Springer Nature |
| Total Pages | : 187 |
| Release | : 2019-09-02 |
| Genre | : Medical |
| ISBN | : 3030223310 |
Compartment syndrome is a complex physiologic process with significant potential harm, and though an important clinical problem, the basic science and research surrounding this entity remains poorly understood. This unique open access book fills the gap in the knowledge of compartment syndrome, re-evaluating the current state of the art on this condition. The current clinical diagnostic criteria are presented, as well as the multiple dilemmas facing the surgeon. Pathophysiology, ischemic thresholds and pressure management techniques and limitations are discussed in detail. The main surgical management strategy, fasciotomy, is then described for both the upper and lower extremities, along with wound care. Compartment syndrome due to patient positioning, in children and polytrauma patients, and unusual presentations are likewise covered. Novel diagnosis and prevention strategies, as well as common misconceptions and legal ramifications stemming from compartment syndrome, round out the presentation. Unique and timely, Compartment Syndrome: A Guide to Diagnosis and Management will be indispensable for orthopedic and trauma surgeons confronted with this common yet challenging medical condition.
| Author | : R. Gilberto González |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 299 |
| Release | : 2010-10-05 |
| Genre | : Medical |
| ISBN | : 3642127517 |
This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.
| Author | : Morris Karmazyn |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 538 |
| Release | : 1996-08-28 |
| Genre | : Medical |
| ISBN | : 9783764352691 |
Myocardial ischemia and subsequent reperfusion of the ischemic myocardium represent complex phenomena encompassing numerous physiological processes. This book aims at enhancing our understanding of these processes and stresses recent important developments in this very active area of research. The concise, state-of-the-art reviews cover recent advances in many fields important to the area of myocardial ischemia and reperfusion including physiology, pathology, pharmacology, biochemistry and molecular biology with reference to clinical relevance and applicability of these findings. Major areas which are highlighted include vascular mechanisms resulting in myocardial ischemia, cellular events in the ischemic, postinfarcted and reperfused myocardium as well as new exciting developments in cardiac protection that involve both novel pharmacological approaches as well as endogenous cardioprotective mechanisms such as preconditioning. Aimed at both the basic and clinical cardiovascular investigator, the book comprehensively reviews the rapid progress made in recent years in understanding the etiology of myocardial ischemia and reperfusion. It will further serve as an authoritative reference for all those interested in learning about the important developments in the treatment of myocardial ischemic and reperfusion disorders.
| Author | : Kenneth J. Drobatz |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1520 |
| Release | : 2018-10-11 |
| Genre | : Medical |
| ISBN | : 1119028957 |
Textbook of Small Animal Emergency Medicine offers an in-depth understanding of emergency disease processes and the underlying rationale for the diagnosis, treatment, monitoring, and prognosis for these conditions in small animals. A comprehensive reference on a major topic in veterinary medicine The only book in this discipline to cover the pathophysiology of disease in depth Edited by four respected experts in veterinary emergency medicine A core text for those studying for specialty examinations Includes access to a website with video clips, additional figures, and the figures from the book in PowerPoint Textbook of Small Animal Emergency Medicine offers an in-depth understanding of emergency disease processes and the underlying rationale for the diagnosis, treatment, monitoring, and prognosis for these conditions in small animals.
| Author | : Pierce A. Grace |
| Publisher | : Wiley-Blackwell |
| Total Pages | : 400 |
| Release | : 1999-02-04 |
| Genre | : Medical |
| ISBN | : 9780632050215 |
Ischaemia-Reperfusion Injury is concerned with the consequences of interrupting and restoring blood flow to tissues. Many common clinical conditions are caused by interruption of blood flow to tissues (eg, ischaemic heart disease, peripheral vascular disease, stroke); blood flow is also interrupted deliberately in many surgical procedures (eg, cardiac surgery, arterial surgery, transplant surgery, limb surgery with tourniquet). In treating such conditions or after performing such operations the aim of the clinician is to restore the blood supply to the ischaemic tissue. Paradoxically, restoration of blood flow to ischaemic tissues can lead to further tissue damage with the potential for severe local and systemic injury. This book focuses on the clinical, pathological and biochemical processes involved in ischaemia-reperfusion injury and gives an overview of the strategies that may be adopted to mitigate or prevent such injury. This book will be of interest to both clinicians and scientists who have to deal with or have interest in this difficult but important problem.
| Author | : Jean-Marc Cavaillon |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1818 |
| Release | : 2018-02-20 |
| Genre | : Medical |
| ISBN | : 3527338993 |
Dieses Fachbuch erläutert die molekularen Grundlagen von Entzündungen, spannt den Bogen zu Infektionskrankheiten und den Zusammenhang zwischen Entzündungen und chronischen Erkrankungen, behandelt abschließend den Heilungsprozess und zeigt Therapiemöglichkeiten.
| Author | : Reza Behrouz, DO |
| Publisher | : Springer Publishing Company |
| Total Pages | : 301 |
| Release | : 2019-03-26 |
| Genre | : Medical |
| ISBN | : 0826124798 |
Awareness and preparedness for potential complications in the aftermath of acute stroke is as important as initial treatment to achieve favorable clinical outcomes. Complications of Acute Stroke: A Concise Guide to Prevention, Recognition, and Management is the first book to focus exclusively on specific post-acute stroke complications that require timely and urgent attention. This practical, evidence-based guide is written for clinicians who provide in-hospital care to stroke patients and covers the broad range of medical and neurological issues that may manifest in the first 24 to 72 hours following ischemic or hemorrhagic stroke. This book will assist neurologists, neurosurgeons, intensivists, hospitalists, and other team members in the optimal management of acute stroke patients. It provides a roadmap for assessing risk and monitoring, recognizing, and managing emergent problems that can lead to neurological deterioration or worsening. Chapters by specialists on the frontlines are formatted with structured headings that detail pathophysiology, preventive measures, identification, and management strategies. For quick and targeted reference at the point of care, boxed “Key Points”, tables, flowcharts or algorithms, and associated imaging are also included. Key Features: Practical guide to identify complications in acute stroke patients Easy to understand description of the pathophysiology underlying various complications Structured format for quick access to essential content Three-pillar approach of prevention, recognition, and effective management Detailed prevention strategies and treatment interventions for each complication Purchase includes access to the eBook for use on most mobile devices or computer
