This volume interrogates the foundational categories that have come to define medical science in modern South Asia. It seeks to probe issues such as what constitutes the ‘medical’, in which context, and who defines it. This is achieved through case studies that range from the nineteenth to twenty-first centuries, from colonial Bengal and British Burma to present-day Andaman Islands and Ladakh. By examining the close interactions between political authorities, corporeal knowledge, and objects of governance in a sustained manner, the domains of the medical and the non-medical are revealed to be more blurred and porous than apparent. This provides us with new perspectives on the co-production of medicine and social worlds by actors and agencies in specific times and places.