Origin And Spatiotemporal Dynamics Of The Peroxisomal Endomembrane System
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| Author | : Vladimir I Titorenko |
| Publisher | : Frontiers Media SA |
| Total Pages | : 149 |
| Release | : 2015-03-05 |
| Genre | : Physiology |
| ISBN | : 2889194647 |
The peroxisome is an organelle with essential roles in lipid metabolism, maintenance of reactive oxygen species homeostasis, and anaplerotic replenishment of tricarboxylic acid cycle intermediates destined for mitochondria. Peroxisomes constitute a dynamic endomembrane system. The homeostatic state of this system is upheld via two pathways for assembling and maintaining the diverse peroxisomal compartments constituting it; the relative contribution of each pathway to preserving such system may vary in different organisms and under various physiological conditions. One pathway begins with the targeting of certain peroxisomal membrane proteins to an endoplasmic reticulum template and their exit from the template via pre-peroxisomal carriers; these carriers mature into metabolically active peroxisomes containing the entire complement of membrane and matrix proteins. Another pathway operates via growth and maturation of pre-existing peroxisomal precursors that do not originate from the endoplasmic reticulum; mature peroxisomes proliferate by undergoing fission. Recent studies have uncovered new roles for the peroxisomal endomembrane system in orchestrating important developmental decisions and defining organismal longevity. This Frontiers Special Topic Issue is focused on the advances in our understanding of how evolutionarily distant organisms coordinate the formation, maturation, proliferation, maintenance, inheritance and quality control of the peroxisomal endomembrane system and how peroxisomal endomembranes communicate with other cellular compartments to orchestrate complex biological processes and various developmental programs from inside the cell.
| Author | : Claudia Tanja Mierke |
| Publisher | : Springer Nature |
| Total Pages | : 919 |
| Release | : 2020-10-30 |
| Genre | : Science |
| ISBN | : 3030585328 |
This book focuses on the mechanical properties of cells, discussing the basic concepts and processes in the fields of immunology, biology, and biochemistry. It introduces and explains state-of-the-art biophysical methods and examines the role of mechanical properties in the cell/protein interaction with the connective tissue microenvironment. The book presents a unique perspective on cellular mechanics and biophysics by combining the mechanical, biological, physical, biochemical, medical, and immunological views, highlighting the importance of the mechanical properties of cells and biophysical measurement methods. The book guides readers through the complex and growing field of cellular mechanics and biophysics, connecting and discussing research findings from different fields such as biology, cell biology, immunology, physics, and medicine. Featuring suggestions for further reading throughout and addressing a wide selection of biophysical topics, this book is an indispensable guide for graduate and advanced undergraduate students in the fields of cellular mechanics and biophysics.
| Author | : Vladimir I. Titorenko |
| Publisher | : Frontiers E-books |
| Total Pages | : 102 |
| Release | : |
| Genre | : |
| ISBN | : 2889190900 |
Aging of multicellular and unicellular eukaryotic organisms is a highly complex biological phenomenon that affects a plethora of processes within cells. This wide array of longevity-defining cellular processes - which are governed by an evolutionarily conserved signaling network - includes oxidative metabolism and protein synthesis in mitochondria, lipid and carbohydrate metabolism, NAD+ homeostasis, amino acid biosynthesis and degradation, ammonium and amino acid uptake, ribosome biogenesis and translation, proteasomal protein degradation, nuclear DNA replication, chromatin assembly and maintenance, actin organization, apoptosis, necrosis, autophagy, protein folding, stress response, signal transduction, cell cycle, and cell growth. The focus of this Frontiers Special Topic Issue is on an important conceptual advance in our understanding of how cells integrate and control these numerous processes and how genetic, dietary and pharmacological anti-aging interventions extend longevity by altering their functional states and spatiotemporal dynamics. The Issue will highlight the various strategies used by evolutionarily diverse organisms for coordinating these longevity-defining cellular processes in space and time, critically evaluate the molecular and cellular mechanisms underlying such coordination, and outline the most important unanswered questions and directions for future research in this vibrant and rapidly evolving field.
| Author | : Kwang W. Jeon |
| Publisher | : Academic Press |
| Total Pages | : 427 |
| Release | : 2011-09-06 |
| Genre | : Science |
| ISBN | : 0080885365 |
International Review of Cell & Molecular Biology presents current advances and comprehensive reviews in cell biology—both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth.* Authored by some of the foremost scientists in the field * Provides up-to-date information and directions for future research * Valuable reference material for advanced undergraduates, graduate students and professional scientists
| Author | : |
| Publisher | : |
| Total Pages | : 656 |
| Release | : 2006 |
| Genre | : Cytology |
| ISBN | : |
No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-
| Author | : A. Baker |
| Publisher | : Springer |
| Total Pages | : 505 |
| Release | : 2013-01-08 |
| Genre | : Science |
| ISBN | : 9789401598590 |
In the two decades since the last comprehensive work on plant peroxisomes appeared, the scientific approaches employed in the study of plant biology have changed beyond all recognition. The accelerating pace of plant research in the post-genomic era is leading us to appreciate that peroxisomes have many important roles in plant cells, including reserve mobilisation, nitrogen assimilation, defence against stress, and metabolism of plant hormones, which are vital for productivity and normal plant development. Many plant scientists are finding, and will no doubt continue to find, that their own area of research is connected in some way to peroxisomes. Written by the leading experts in the field, this book surveys peroxisomal metabolic pathways, protein targeting and biogenesis of the organelle and prospects for the manipulation of peroxisomal function for biotechnological purposes. It aims to draw together the current state of the art as a convenient starting point for anyone, student or researcher, who wishes to know about plant peroxisomes.
| Author | : Govind Singh Saharan |
| Publisher | : Springer Nature |
| Total Pages | : 414 |
| Release | : 2019-11-22 |
| Genre | : Science |
| ISBN | : 9811398534 |
Powdery mildew disease is the fourth most widespread disease in cruciferous crops and a devastating effect, causing significant losses in terms of quality and quantity in rapeseed and mustard. Powdery mildews are also a favourable host-pathosystem model for basic research on host–parasite interactions, developmental morphology, cytology, and molecular biology to identify the effector proteins/genes governing different biological functions. This book provides a comprehensive overview of all the published information in the field for researchers, teachers, students, extension experts, industrialists and farmers, and includes illustrations, photographs, graphs, figures, tables, histograms, micrographs, electron micrographs, and flow charts to aid understanding. It also describes standardized reducible techniques. The book discusses each disease in detail, describing the distribution, symptomatology, host range, yield losses and disease assessment, as well as the taxonomy, morphology, phylogeny, variability, sporulation, survival and perpetuation of the pathogen. Further, it explores topics such as spore germination; infection; pathogenesis; disease cycle; epidemiology; forecasting; fine structures; host resistance; biochemical, histological, genetic and molecular aspects such as cloning and mapping of R genes; sources of resistance; disease resistance breeding; and the genetics of host-parasite interactions and disease management.
| Author | : Jure Piškur |
| Publisher | : Springer |
| Total Pages | : 328 |
| Release | : 2014-05-06 |
| Genre | : Science |
| ISBN | : 3642550134 |
Yeast is one of the most studied laboratory organisms and represents one of the most central models to understand how any eukaryote cell works. On the other hand, yeast fermentations have for millennia provided us with a variety of biotech products, like wine, beer, vitamins, and recently also with pharmaceutically active heterologous products and biofuels. A central biochemical activity in the yeast cell is the metabolism of carbon compounds, providing energy for the whole cell, and precursors for any of the final fermentation products. A complex set of genes and regulatory pathways controls the metabolism of carbon compounds, from nutrient sensing, signal transduction, transcription regulation and post-transcriptional events. Recent advances in comparative genomics and development of post-genomic tools have provided further insights into the network of genes and enzymes, and molecular mechanisms which are responsible for a balanced metabolism of carbon compounds in the yeast cell, and which could be manipulated in the laboratory to increase the yield and quality of yeast biotech products. This book provides a dozen of most comprehensive reviews on the recent developments and achievements in the field of yeast carbon metabolism, from academic studies on gene expression to biotechnology relevant topics.
| Author | : J.C. Kader |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 598 |
| Release | : 2013-04-18 |
| Genre | : Science |
| ISBN | : 9401583943 |
A collection of papers that comprehensively describe the major areas of research on lipid metabolism of plants. State-of-the-art knowledge about research on fatty acid and glycerolipid biosynthesis, isoprenoid metabolism, membrane structure and organization, lipid oxidation and degradation, lipids as intracellular and extracellular messengers, lipids and environment, oil seeds and gene technology is reviewed. The different topics covered show that modern tools of plant cellular and molecular biology, as well as molecular genetics, have been recently used to characterize several key enzymes of plant lipid metabolism (in particular, desaturases, thioesterases, fatty acid synthetase) and to isolate corresponding cDNAs and genomic clones, allowing the use of genetic engineering methods to modify the composition of membranes or storage lipids. These findings open fascinating perspectives, both for establishing the roles of lipids in membrane function and intracellular signalling and for adapting the composition of seed oil to the industrial needs. This book will be a good reference source for research scientists, advanced students and industrialists wishing to follow the considerable progress made in recent years on plant lipid metabolism and to envision the new opportunities offered by genetic engineering for the development of novel oil seeds.
| Author | : John M. Graham |
| Publisher | : Oxford University Press |
| Total Pages | : 360 |
| Release | : 1997 |
| Genre | : Medical |
| ISBN | : 0199634947 |
In the fast changing world of cell biology it is often required that particular membranes or subcellular organisms be isolated from the structure for investigative purposes. This book shows how to do this in a practical, hands-on way.
