Oecd Series On Testing And Assessment Guidance Document For The Use Of Adverse Outcome Pathways In Developing Integrated Approaches To Testing And Assessment Iata
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Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 33 |
Release | : 2017-03-10 |
Genre | : |
ISBN | : 9264891048 |
The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of Integrated Approaches for Testing and Assessment (IATA). However, there is a need for a systematic framework to characterise the individual biological and toxicological relevance of alternative methods in assessing chemicals in predicting toxicological endpoints.
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 23 |
Release | : 2017-04-13 |
Genre | : |
ISBN | : 9264274820 |
With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides a set of principles for reporting defined approaches to testing and assessment that can be used as one of ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 154 |
Release | : 2017-04-13 |
Genre | : |
ISBN | : 926427474X |
This document is a report of the Workshop on a framework for the development and use of integrated approaches to testing and assessment which was held on 17-19 November 2014 in Crystal City VA, USA. This framework should provide guiding principles, and technical guidance on how results from ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 29 |
Release | : 2017-04-13 |
Genre | : |
ISBN | : 9264274812 |
OECD member countries have been making efforts to expand the use of alternative methods in assessing chemicals. The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of ...
Author | : Hajime Kojima |
Publisher | : Springer |
Total Pages | : 130 |
Release | : 2018-12-27 |
Genre | : Medical |
ISBN | : 9811324476 |
This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 311 |
Release | : 2017-07-11 |
Genre | : |
ISBN | : 9264279288 |
With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides guidance on the reporting of defined approaches to testing and assessment in the area of skin ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 692 |
Release | : 2018-09-03 |
Genre | : |
ISBN | : 9264304746 |
This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals.
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 206 |
Release | : 2018-12-10 |
Genre | : |
ISBN | : 9264304797 |
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 64 |
Release | : 2017-04-13 |
Genre | : |
ISBN | : 9264274693 |
This Guidance Document proposes an integrated approach on testing and assessment (IATA) for skin corrosion and irritation. It also provides consistent information on key characteristics of each of the individual information sources of the IATA, and relevant guidance on how to integrate ...
Author | : Aditya Bhushan Pant |
Publisher | : Springer Nature |
Total Pages | : 266 |
Release | : 2023-08-28 |
Genre | : Medical |
ISBN | : 9819928044 |
Efforts are being made by research organizations and cosmetic industries worldwide to develop more precise and targeted 3D models that mimic humans for testing cosmetic and personal health care product ingredients, following a complete ban on animal testing. This book includes several subtopics dedicated to the progress made, challenges faced, roadblocks encountered, and future prospects in the development and validation of 3D models for testing these products. The book consist of an editorial and 14 themed chapters that will showcase the significant progress made so far, challenges encountered, and future prospects in the development of 3D reconstruct models.