NTM – The New Uber-Bugs

NTM – The New Uber-Bugs
Author: Veronique Dartois
Publisher: Frontiers Media SA
Total Pages: 240
Release: 2019-11-04
Genre:
ISBN: 2889630129

Incidence of pulmonary disease caused by nontuberculous mycobacteria (NTM), such as Mycobacterium abscessus and M. avium, is increasing at an alarming rate, surpassing tuberculosis (TB) in many countries. Treatment durations are extremely long. With low sputum conversion rates, the outcomes are often disappointing. Thus, NTM disease resembles extremely drug resistant TB. There is an urgent need for increased research on this dreadful disease. For this book we brought together experts from a wide range of disciplines addressing current status, gaps and needs, and new developments in several NTM-relevant research areas. We start with the discussion of NTM disease presentations and clinical research. This is followed by contributions on epidemiology, antibiotic resistance mechanisms, drug discovery and development, bacteriology and targets, and new diagnostic tools. We would like to thank the 130 authors for sharing their work and insights. We hope that this collection of articles will stimulate discussions and research activities on the challenging lung disease caused by the diverse group of pathogens called NTM.

Never Home Alone

Never Home Alone
Author: Rob Dunn
Publisher: Basic Books
Total Pages: 343
Release: 2018-11-06
Genre: Science
ISBN: 154164574X

A natural history of the wilderness in our homes, from the microbes in our showers to the crickets in our basements Even when the floors are sparkling clean and the house seems silent, our domestic domain is wild beyond imagination. In Never Home Alone, biologist Rob Dunn introduces us to the nearly 200,000 species living with us in our own homes, from the Egyptian meal moths in our cupboards and camel crickets in our basements to the lactobacillus lounging on our kitchen counters. You are not alone. Yet, as we obsess over sterilizing our homes and separating our spaces from nature, we are unwittingly cultivating an entirely new playground for evolution. These changes are reshaping the organisms that live with us -- prompting some to become more dangerous, while undermining those species that benefit our bodies or help us keep more threatening organisms at bay. No one who reads this engrossing, revelatory book will look at their homes in the same way again.

Sandworm

Sandworm
Author: Andy Greenberg
Publisher: Anchor
Total Pages: 370
Release: 2020-10-20
Genre: Computers
ISBN: 0525564632

"With the nuance of a reporter and the pace of a thriller writer, Andy Greenberg gives us a glimpse of the cyberwars of the future while at the same time placing his story in the long arc of Russian and Ukrainian history." —Anne Applebaum, bestselling author of Twilight of Democracy The true story of the most devastating act of cyberwarfare in history and the desperate hunt to identify and track the elite Russian agents behind it: "[A] chilling account of a Kremlin-led cyberattack, a new front in global conflict" (Financial Times). In 2014, the world witnessed the start of a mysterious series of cyberattacks. Targeting American utility companies, NATO, and electric grids in Eastern Europe, the strikes grew ever more brazen. They culminated in the summer of 2017, when the malware known as NotPetya was unleashed, penetrating, disrupting, and paralyzing some of the world's largest businesses—from drug manufacturers to software developers to shipping companies. At the attack's epicenter in Ukraine, ATMs froze. The railway and postal systems shut down. Hospitals went dark. NotPetya spread around the world, inflicting an unprecedented ten billion dollars in damage—the largest, most destructive cyberattack the world had ever seen. The hackers behind these attacks are quickly gaining a reputation as the most dangerous team of cyberwarriors in history: a group known as Sandworm. Working in the service of Russia's military intelligence agency, they represent a persistent, highly skilled force, one whose talents are matched by their willingness to launch broad, unrestrained attacks on the most critical infrastructure of their adversaries. They target government and private sector, military and civilians alike. A chilling, globe-spanning detective story, Sandworm considers the danger this force poses to our national security and stability. As the Kremlin's role in foreign government manipulation comes into greater focus, Sandworm exposes the realities not just of Russia's global digital offensive, but of an era where warfare ceases to be waged on the battlefield. It reveals how the lines between digital and physical conflict, between wartime and peacetime, have begun to blur—with world-shaking implications.

Zoological Catalogue of Australia

Zoological Catalogue of Australia
Author:
Publisher:
Total Pages: 532
Release: 1983
Genre: Animals
ISBN:

The published works are derived from the Zoological catalogue of Australia database. Taxa in the Australian fauna are divided among volumes to form sets of about 1800-2000 species available names, such that each volume comprises the whole or part of one or more major groups.

Microbial Growth in Drinking Water Supplies

Microbial Growth in Drinking Water Supplies
Author: Dick van der Kooij
Publisher: IWA Publishing
Total Pages: 484
Release: 2013-09-14
Genre: Science
ISBN: 1780400403

Maintaining the microbial quality in distribution systems and connected installations remains a challenge for the water supply companies all over the world, despite many years of research. This book identifies the main concerns and knowledge gaps related to regrowth and stimulates cooperation in future research. Microbial Growth in Drinking Water Supplies provides an overview of the regrowth issue in different countries and the water quality problems related to regrowth. The book assesses the causes of regrowth in drinking water and the prevention of regrowth by water treatment and distribution. Editors: Dirk van der Kooij and Paul W.J.J. van der Wielen, KWR Watercycle Research Institute, The Netherlands

The Ecology of Mycobacteria

The Ecology of Mycobacteria
Author: J. Kazda
Publisher: Springer Science & Business Media
Total Pages: 79
Release: 2012-12-06
Genre: Science
ISBN: 9401141029

Detailed information dealing with the ecology of mycobacteria is derived from a variety of different scientific fields such as botany, biochemistry, genetics, immunology, microbiology and epidemiology. This is the first attempt to evaluate this information from an ecological point of view and to develop a strategy for the prevention of tuberculosis and other mycobacterioses based on the ecological behavior of mycobacteria, especially the potentially pathogenic species capable of either growth in the environment or provoking disease. Regarding the interests of the developing countries, special attention is paid to the ecology of Mycobacterium leprae and to the supporting effect of accompanying mycobacteria in its pathogenicity. On a more positive side, environmental mycobacteria play an important role in the ecology of moorland dragonflies. Such a book is needed for specialists working in the field of mycobacterial research, clinical laboratories, the public health service, food hygiene, the water industry and in general ecology.

Relativity and Scientific Computing

Relativity and Scientific Computing
Author: Friedrich W Hehl
Publisher: Springer
Total Pages: 389
Release: 2012-02-12
Genre: Science
ISBN: 9783642957345

For this set of lectures we assumed that the reader has a reasonable back ground in physics and some knowledge of general relativity, the modern theory of gravity in macrophysics, and cosmology. Computer methods are present ed by leading experts in the three main domains: in numerics, in computer algebra, and in visualization. The idea was that each of these subdisciplines is introduced by an extended set of main lectures and that each is conceived as being of comparable 'importance. Therefpre we believe that the book represents a good introduction into scientific I computing for any student who wants to specialize in relativity, gravitation, and/or astrophysics. We took great care to select lecturers who teach in a comprehensible way and who are, at the same time, at the research front of their respective field. In numerics we had the privilege of having a lecturer from the National Center for Supercomputing Applications (NCSA, Champaign, IL, USA) and some from other leading institutions of the world; visualization was taught by a visualization expert from Boeing; and in com puter algebra we took recourse to practitioners of different computer algebra systems as applied to classical general relativity up to quantum gravity and differential geometry.

Exploring Digital Design

Exploring Digital Design
Author: Ina Wagner
Publisher: Springer Science & Business Media
Total Pages: 294
Release: 2010-08-12
Genre: Computers
ISBN: 1849962235

Exploring Digital Design takes a multi-disciplinary look at digital design research where digital design is embedded in a larger socio-cultural context. Working from socio-technical research areas such as Participatory Design (PD), Computer Supported Cooperative Work (CSCW) and Human-Computer Interaction (HCI), the book explores how humanities offer new insights into digital design, and discusses a variety of digital design research practices, methods, and theoretical approaches spanning established disciplinary borders. The aim of the book is to explore the diversity of contemporary digital design practices in which commonly shared aspects are interpreted and integrated into different disciplinary and interdisciplinary conversations. It is the conversations and explorations with humanities that further distinguish this book within digital design research. Illustrated with real examples from digital design research practices from a variety of research projects and from a broad range of contexts Exploring Digital Design offers a basis for understanding the disciplinary roots as well as the interdisciplinary dialogues in digital design research, providing theoretical, empirical, and methodological sources for understanding digital design research. The first half of the book Exploring Digital Design is authored as a multi-disciplinary approach to digital design research, and represents novel perspectives and analyses in this research. The contributors are Gunnar Liestøl, Andrew Morrison and Christina Mörtberg in addition to the editors. Although primarily written for researchers and graduate students, digital design practioners will also find the book useful. Overall, Exploring Digital Design provides an excellent introduction to, and resource for, research into digital design.