Nitric Oxide Part A
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| Author | : Louis J. Ignarro |
| Publisher | : Academic Press |
| Total Pages | : 1023 |
| Release | : 2000-09-13 |
| Genre | : Medical |
| ISBN | : 0080525032 |
Nitric oxide (NO) is a gas that transmits signals in an organism. Signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems. NO is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. NO also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. NO is present in most living creatures and made by many different types of cells. NO research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. This book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications. - Edited by Nobel Laureate Louis J. Ignarro, editor of the Academic Press journal, Nitric Oxide - Authored by world experts on nitric oxide - Includes an overview of basic principles of biology and chemical biology - Covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense
| Author | : Vijay Pratap Singh |
| Publisher | : Academic Press |
| Total Pages | : 848 |
| Release | : 2021-09-19 |
| Genre | : Science |
| ISBN | : 0128187980 |
Nitric Oxide in Plant Biology: An Ancient Molecule with Emerging Roles is an extensive volume which provides a broad and detailed overview of Nitric Oxide (NO) in plant biology. The book covers the entirety of the crucial role NO plays in the plant lifecycle, from the regulation of seed germination and growth to synthesis, nitrogen fixation and stress response. Beginning with NO production and NO homeostasis, Nitric Oxide in Plant Biology goes on to cover a variety of NO roles, with a focus on NO signalling, crosstalk and stress responses. Edited by leading experts in the field and featuring the latest research from laboratories from across the globe, it is a comprehensive resource of interest to students and researchers working in plant physiology, agriculture, biotechnology, and the pharmaceutical and food industries. - Provides a broad and detailed overview on NO in plant biology, including NO production, NO signaling, NO homeostasis, crosstalk and stress responses - Edited by leading experts in the field - Features the latest research from laboratories from across the globe
| Author | : Ernst van Faassen |
| Publisher | : Elsevier |
| Total Pages | : 444 |
| Release | : 2011-10-13 |
| Genre | : Science |
| ISBN | : 0080489591 |
Radicals for Life: the Various Forms of Nitric Oxide provides an up-to-date overview of the role of nitrosocompounds and nitrosyl-iron complexes in physiology. Nitrosocompounds can be considered as stabilised forms of nitric oxide, one of the most important regulatory molecules in physiology today. Many nitrosocompounds share some of the physiological functions of nitric oxide, and may be formed inside living organisms. This is the first book to be published that is dedicated to the role of such nitrosocompounds in physiology, with particular emphasis on the nitrosocompounds that are endogenously formed in higher organisms and humans. Points of discussion include: physical and chemical properties of the compounds, the main chemical pathways in vivo, as well as the physiological effects that have been recognised to date. Each of the nineteen chapters is written by distinguished specialists in the field, well known for their original and important contributions to the subject. Also included are results from a wide range of studies in vitro, in cell cultures, animal models and human volunteers. Examples of alternative forms of nitric oxide, with special emphasis on their protective role against widespread human diseases like atherosclerosis, Alzheimer's disease, diabetes, sexual dysfunction, and renal insufficiency to stroke and ischemia are also included. - First monograph to consider and provide an overview of endogenous nitrosocompounds and nitrosyl-iron complexes - Extensive bibliographic references, written by specialists of human physiology - Providing high scientific quality with a focus on implications for human diseases
| Author | : |
| Publisher | : World Health Organization |
| Total Pages | : 488 |
| Release | : 2010 |
| Genre | : House & Home |
| ISBN | : |
This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.
| Author | : Jack Lancaster Jr. |
| Publisher | : Elsevier |
| Total Pages | : 373 |
| Release | : 1996-07-27 |
| Genre | : Science |
| ISBN | : 0080537545 |
This unique sourcebook serves as a comprehensive reference, bridging the well-established chemistry of nitric oxide and the new and exciting role of nitric oxide as an effector and signaling molecule in numerous biological systems. Nitric Oxide: Principles and Actions relates the chemical properties of the molecule to its possible effects on biological systems, under both normal physiological and pathophysiological conditions. Combining the chemistry and analysis of nitric oxide with newer studies of the relevance of the molecule gives this book a long life, making it extremely useful to researchers in a number of areas. - Provides a much needed compilation of what is known about nitric oxide and its properties - Enables researchers to understand the importance and use of nitric oxide in systems of study - Covers an area of tremendous growth in research - Provides the first collection of the roles of nitric oxide in microbial and mammalian systems and as a probe of metalloenzymes - Presents the historically important role of nitric oxide in food preservation
| Author | : Amedea Seabra |
| Publisher | : Academic Press |
| Total Pages | : 367 |
| Release | : 2017-03-17 |
| Genre | : Medical |
| ISBN | : 0128134593 |
Nitric Oxide Donors: Biomedical Applications and Perspectives presents the current state of art, challenges and innovations in the design of therapeutics nitric oxide donors with great impact in several aspects of human physiology and pathophysiology. Although considerable innovative progress has been achieved using Nitric Oxide donors in biomedical applications, certain drawbacks still need to be overcome to successfully translate these research innovations into clinical applications. This book encompasses several topics on nitric oxide such as its sources and biological properties; its performance in the cardiovascular and neurologic systems, in the human skin and its application in the treatment of neglected diseases, neurodegenerative disorders, and cancer. Additionally, it covers its role in inflammation and immunity, penile erection function, photodynamic therapy, antimicrobial activities. It also discusses the future of nitric oxide donors in combination with other therapeutic drugs, in implantable sensors, and nitric oxide releasing hydrogels and medical devices for topical applications. The book is a valuable source for researchers on different areas of biomedical field who are interested in the improvements that these molecules can make in the treatment of several conditions. - Provides background information about biology and chemistry of nitric oxide - Discusses the state-of-the-art in the design of nitric oxide releasing nanomaterials for biomedical applications - Covers the usage of nitric oxide donors in the treatment of several conditions, such as cancer, human skin, cardiovascular system, and immunity - Discusses the future of nitric oxide donors and their FDA approval
| Author | : M. Nasir Khan |
| Publisher | : Springer |
| Total Pages | : 310 |
| Release | : 2014-05-27 |
| Genre | : Science |
| ISBN | : 3319067109 |
This book covers the key features of nitric oxide (NO) in plants. Comprising nine chapters, Part I highlights its metabolism and identification in plants. Part II, which consists of eight chapters, focuses on the chemical, physical and biochemical properties of the NO molecule and its derivatives; on its functional role and mode of action; and on its signaling and interaction with phytohormones, mineral nutrients, biomolecules, ions and ion channels in plants under abiotic stresses. Combining the expertise of leading researchers in the field, the book provides a concise overview of plant NO biology and offers a valuable reference work.
| Author | : Nathan Bryan |
| Publisher | : |
| Total Pages | : 170 |
| Release | : 2010-11 |
| Genre | : Health & Fitness |
| ISBN | : 9780615417134 |
Eighty-one million Americans have cardiovascular disease, the arterial damage that leads to the heart attacks and strokes that account for 36 percent of all deaths in the U.S. But few people know that boosting the body's levels of a single molecule of nitric oxide can help prevent, control, and even reverse cardiovascular disease.
| Author | : |
| Publisher | : DIANE Publishing |
| Total Pages | : 57 |
| Release | : 1999 |
| Genre | : |
| ISBN | : 1428902805 |
| Author | : Nathan S. Bryan |
| Publisher | : DEStech Publications, Inc |
| Total Pages | : 239 |
| Release | : 2010 |
| Genre | : Medical |
| ISBN | : 1932078843 |
This book provides a scientific analysis of the effects of foods and nutrients on the NO pathway in humans. Contributors to the book clarify novel chemical and biochemical connections between dietary intake and nitric oxide, particularly in cases of NO deficiency. In this context, the book addresses how specific foods can restore nitric oxide production and bioactivity—without medical interventions. A variety of evidential data is presented showing how NO-rich dietary elements are implicated in disease prevention and modulation. The book offers new knowledge for food technologists, food manufacturers, nutrition researchers, and healthcare practitioners. From the Foreword by Louis J. Ignarro, Nobel Laureate in Physiology/Medicine "The body of work contained in this volume, linking NO to food and nutrition, may have revolutionary implications in terms of developing strategies to combat heart disease and many other contemporary diseases associated with NO deficiency. Proving that a natural and inexpensive regimen of foods rich in nitric oxide activity does restore NO homeostasis can have profound effects on human health…The research presented in this text provides an important expansion of NO work…(and) Dr. Nathan Bryan, the editor…is to be congratulated for…communicating new knowledge and assembling the world's experts in their fields."
